Common-passage liquid injection device

Abstract

The invention relates to the technical field of biology, in particular to a common-passage liquid injection device. The common-passage liquid injection device comprises a main body plate, wherein a plurality of first liquid inlet parts penetrating through the main body plate are arranged on one surface of the main body plate; a plurality of second liquid inlet parts are arranged on the other surface adjacent to the surface; and the second liquid inlet parts extend to communicate with the first liquid inlet parts. Two reaction reagents of the common-passage liquid injection device can be injected into a composite column respectively through the first liquid inlet parts and the second liquid inlet parts; before the two reaction reagents are injected into the composite column, the premixing can be realized; the activation on the reagents can be further completed; the synthesis effects of RNA, LNA and DNA are improved to a certain degree; after the injection of the first group of reagentsis completed, the liquid injection device is moved; and then, the injection of the second group of reagents is performed, so that the injection of each group of reagents can be sequentially completedin a short time. In addition, by using a mode of simultaneously injecting the two reagents into the synthesis column, the liquid adding time is shortened to a certain degree; and the synthesis efficiency is improved.

Description

technical field [0001] The invention relates to the field of biotechnology, in particular to a common-channel infusion device. Background technique [0002] Chinese scientists completed the total synthesis of yeast alanine tRNA in 1981. This is the world's first artificially synthesized RNA molecule with full biological activity. Artificially synthesized DNA and LNA are also known methods for directional modification of gene sequences. The only way, widely used in many fields such as protein modification and life science, such as nucleic acid drug, enzyme engineering, gene detection, gene therapy, etc. In the process of RNA, LNA and DNA synthesis, a series of reactions such as deprotection, activation linkage, capping and oxidation are required, and various reactions require high reaction conditions. For example, during the synthesis process, it is necessary to inject different reagents into the synthesis column under the protection of an inert gas environment, and then emp...

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Problems solved by technology

[0004] The technical problem to be solved by the present invention is to provide a common-channel infusion device to solve the problems that the existing RNA, LNA and DNA synthesizer infusion devices cannot infuse at the same time and the infusion time is long

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