Medicine for improving protection effect of animal vaccines

Abstract

The present invention provides a medicine for improving a protection effect of animal vaccines. The medicine for improving the protection effect of the animal vaccines comprises the following steps: three immunizations for animals to be protected, extraction, then three immunizations for mammals, production of anti-antibodies, and anti-antibody immunization; the extraction is as follows: on the 14th day after the three immunizations, blood is collected in living body or sacrificed body and IgG against canine distemper is extracted and purified; the IgG against the canine distemper has a purityof 95% or more and a neutralization titer of more than or equal to 64; and an immune dose is 10<5> TCID<50>/ml. The anti-antibodies are introduced into the vaccines, ensure that animals with early nest-separation do not show an immune blank period and also ensure that the animals with late nest-separation have an immune failure problem caused by interference of maternal antibodies; besides, the vaccines are modified and any inconvenience in use is not caused; and the medicine solves a problem of immune time to fur animals of newborn minks, etc. in production and can also guarantee a good immune effect.

Description

technical field [0001] The invention belongs to the field of production and application of animal vaccines, and relates to a medicine for improving the protective effect of animal vaccines. Background technique [0002] Mink, fox, raccoon and other wild animals have been domesticated and can be bred artificially, but the wildness of these animals is much stronger than that of pigs, cows, sheep, chickens and other early domesticated animals. One of the obvious characteristics is their The gestation period varies: for example, the mink is 37-85 days, with an average of 47 days; the silver black fox is 50-61 days, the blue fox is 50-58 days, with an average of 51-52 days, and the raccoon is 50-70 days , with an average gestation period of 60 days. Not only that, but the estrus and mating time of animals will be different, so the calving time range of animals often spans a large range. [0003] Animals need to be reared in separate litters after weaning. At this time, the leve...

AI Technical Summary

Problems solved by technology

[0016] The invention provides a medicine for improving the protective effect of animal vaccines, and anti-antibodies are introduced into the vaccine, which solves the problem of immunization time for newborn mink and other fur animals during production