Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

A kind of nano-selenium hydrosol and its preparation method and application

A technology of hydrosol and nano-selenium, which is applied in the fields of applications, pharmaceutical formulations, active ingredients of sulfur/selenium/tellurium, etc., can solve the problems of nano-selenium and bone health that are rarely reported, and achieve good particle size regulation and stabilization, strong Physical adsorption, enhance the effect of curative effect

Active Publication Date: 2022-04-15
THE HONG KONG POLYTECHNIC UNIV SHENZHEN RES INST
View PDF4 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, so far, there are still few reports on the relationship between nano-selenium and bone health.
[0005] The existing methods for preparing nano-elemental selenium usually adopt the reduction method, using selenium oxysalts or oxides to obtain elemental selenium through various reducing agents, and at the same time using modifiers or regulators to modify and regulate the morphology to obtain ideal particle sizes and morphology of the product, but the resulting product is not functionalized nano-selenium

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • A kind of nano-selenium hydrosol and its preparation method and application
  • A kind of nano-selenium hydrosol and its preparation method and application
  • A kind of nano-selenium hydrosol and its preparation method and application

Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0045] In one embodiment of the present invention, the present invention provides a kind of preparation method of nano selenium hydrosol, it comprises the following steps:

[0046] (i) Add selenium dioxide solution or selenite solution to the polysaccharide protein solution of Cordyceps mycelium Cs4, and mix uniformly to obtain mixed solution A; Silk Cs4 obtained;

[0047] (ii) Add vitamin C solution to mixed solution A, mix well, and obtain mixed solution B;

[0048] (iii) After the reaction of the mixed solution B is complete, the nano-selenium hydrosol is obtained through dialysis.

[0049] In the above step (i), the polysaccharide protein of Cordyceps mycelium Cs4 can be prepared by the following method: add water to the Cordyceps mycelium Cs4 according to the ratio of the weight ratio of the Cordyceps mycelium Cs4 to water is 1:20, Heat to 95-100°C, extract for 2 hours and take the filtrate; repeat the extraction of the filter residue once according to the previous step...

Embodiment 1～5

[0064] Its preparation method of nano selenium hydrosol is:

[0065] (1) Under normal temperature and pressure, add sodium selenite solution to the Cs4 polysaccharide protein solution of the Cordyceps mycelium, mix well to obtain a mixed solution A; the Cs4 polysaccharide protein solution of the Cordyceps mycelium is extracted by hot water Mycelium Cs4 is obtained; the specific preparation method of the polysaccharide protein solution of Cordyceps mycelium Cs4 is: according to the weight ratio of Cordyceps mycelium Cs4 and water is 1:20, add water to the Cordyceps mycelium Cs4, heat to 95-100°C, take the filtrate after 2 hours of extraction; repeat the extraction of the filter residue once according to the previous steps, and the repeated extraction time is 2 hours, combine the filtrate obtained from the two extractions, dialyze for 24 hours, the molecular weight cut-off is 8,000, and obtain the Cordyceps sinensis Mycelia Cs4 polysaccharide protein.

[0066] (2) Add the reduc...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

PropertyMeasurementUnit
particle sizeaaaaaaaaaa
particle sizeaaaaaaaaaa
particle sizeaaaaaaaaaa
Login to View More

Abstract

The invention relates to the rapid preparation of novel nano-selenium, in particular to a functionalized nano-selenium hydrosol and its preparation method and application. The preparation method of the novel nano-selenium hydrosol of the present invention comprises the following steps: (i) adding a selenium dioxide solution or a selenite solution to the Cs4 polysaccharide protein solution of the Cordyceps mycelium, and mixing uniformly to obtain a mixed solution A; The above polysaccharide protein solution of Cordyceps mycelium Cs4 is obtained by extracting Cordyceps mycelia Cs4 with water; (ii) adding vitamin C solution to mixed solution A and mixing to obtain mixed solution B; (iii) to be mixed solution B to react Completely, the nano-selenium hydrosol was obtained after dialysis. In the present invention, the Cs4 polysaccharide protein of Cordyceps mycelium with extensive biological activity is used as a nano-selenium functionalization factor to obtain a new nano-selenium hydrosol with the function of promoting bone growth and good stability, which can be used to promote bone development in children and adolescence. Prevention and treatment of osteoporosis, bone loss, fractures and other disease states in middle age.

Description

technical field [0001] The invention relates to the rapid preparation of novel nano-selenium, in particular to a functionalized nano-selenium hydrosol and its preparation method and application. Background technique [0002] Osteoporosis is a metabolic bone disease characterized by decreased bone density and degeneration of bone microarchitecture, leading to increased bone fragility and increased fracture risk. With the aging of the world, osteoporosis has become a serious public health problem, affecting more than 200 million people worldwide, and causing huge economic and medical burdens on society. In 2010, there were more than 23 million cases of fractures caused by osteoporosis in China, and the medical expenses involved were as high as US$10 billion, which is expected to increase significantly to US$25.4 billion in 2050. Therefore, we urgently need to develop a new method to prevent and treat osteoporosis. [0003] Osteoporosis is due to the imbalance of osteogenesis...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Patents(China)
IPC IPC(8): A61K9/06
CPCA61K33/04A61K9/06A61K47/64A61P19/10A61P19/08A23L33/16A23L33/185A23V2002/00A23V2200/306A23V2250/548A23V2250/208A23V2250/1626
Inventor 黄家兴董晓莉陆家谦张兆滔
Owner THE HONG KONG POLYTECHNIC UNIV SHENZHEN RES INST
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com