Rat fixator for bone mineral density instrument measurement through dual-energy X-ray absorption process and manufacturing method

Abstract

The invention discloses a rat fixator for bone mineral density instrument measurement through a dual-energy X-ray absorption process and a manufacturing method. The manufacturing method comprises thefollowing steps: step 1, dissolving organic glass in acetone to form a saturated solution; step 2, preparing a plurality of rats with different weights, killing the rats, placing the rats in a prone state, and shaping the rats in a low-temperature environment; step 3, soaking gauze in the saturated solution for a preset time, taking out the gauze, covering the surfaces of the rats with the gauze,and stretching the gauze to expose the mouth and nose of the rats; step 4, cooling the rats for a preset time to solidify the gauze; step 5, stripping the solidified gauze from the surfaces of the rats to serve as a fixing cover; and step 6, punching a preset position of the organic glass plate with a preset size, arranging a non-metal fixing piece, and fixing the rats to be measured on the organic glass plate through the non-metal fixing piece and the fixing cover. The rat fixator is made of the organic glass, the non-metal fixing piece and the gauze, so that the rat fixator does not absorb X-rays, does not need anesthesia and death of measured rats, and improves the accuracy of measurement and research results.

Description

technical field [0001] The invention relates to the technical field of bone density measurement, in particular to a dual-energy X-ray absorptiometry bone densitometer measuring rat fixator and a manufacturing method. Background technique [0002] Dual-energy X-ray absorptiometry (DXA) bone densitometer is a bone mineral densitometry instrument established on the basis that tissues of different densities absorb different amounts of X-rays when X-rays pass through objects. The new generation of DXA can simultaneously measure muscle and fat content while measuring bone density. The working principle of dual-energy X-ray absorptiometry is to use high-energy and low-energy X-rays to penetrate the human body. The difference in soft tissue is small, and the difference in bone tissue is relatively large. The corresponding probes are counted and processed by the computer. , subtract the high and low energy counts, eliminate the soft tissue counts, and leave the bone tissue counts to...

AI Technical Summary

Problems solved by technology

However, anesthetized rats are prone to anesthesia accidents and increase the mortality of rats. At the same time, it takes a long time for rats to be anesthetized and recovered, resulting in a long time for measurement

Especially when conducting long-term longitudinal observations on the bone density and body fat composition of a large number of rats, the accidental death of rats due to anesthesia during the measurement process will directly affect the experimental results

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