58 results about "Bone mass density" patented technology

The invention relates to an application of plant lactobacillus Hi188 in promotion of bone health. The invention provides the application of the plant lactobacillus Hi188 or the afterbiogen thereof or the composition thereof in increasing the bone mineral density, increasing the bone mineral density, promoting the skeletal development, increasing the bone mineral content and / or promoting the tibia growth. Or preparing food for increasing bone mineral density, increasing bone mineral density, promoting skeletal development, increasing bone mineral content and / or promoting tibia growth; wherein the composition comprises: (A) Phytobacterium plantarum Hi188 or a postbiotic thereof, and (B) Bifidobacterium lactis Ca360 or a postbiotic thereof.

The present invention relates to a diagnosis assistance device and method based on artificial intelligence processing of a radiographic image, wherein a disease diagnosis assistance device according to an embodiment of the present invention may comprise an information providing unit that constructs a diagnosis assistance model by learning a training radiographic image and additional information through a first feature processing unit, a second feature processing unit, and a feature fusion processing unit, determines a bone mineral density value and disease classification information with respect to a radiographic image to be diagnosed on the basis of the diagnosis assistance model, and provides disease diagnosis assistance information including the bone mineral density value, the disease classification information, and diagnosis basis information.

The present application relates to the technical field of dental root image processing, and particularly relates to an intelligent detection method for bone density change caused by dental root absorption area of impacted wisdom tooth. The present application constructs a coordinate system of images under different angles, obtains a gray weighted value of each pixel point in the images under each angle according to actual source image distances of the images under different angles and position distribution of preset anatomical structures, obtains a bone density change rate of each position pixel point in combination with displacement change amounts and gradient features of registered pixel points between the images under different angles, obtains a high risk degree threshold value of bone density change according to bone density change rate distribution of all position pixel points, and obtains a high risk area of bone density change of each image according to the bone density change rate of each position pixel point on each image and the high risk degree threshold value of bone density change. The present application improves the accuracy of bone density change detection by accurately analyzing the bone density change area.

The utility model relates to a bone mineral density ultrasonic detection device which comprises an adjusting seat fixedly arranged on a bottom plate and a calcaneus bone mineral density instrument arranged on the bottom plate in a left-right sliding mode, a seat is arranged on the adjusting seat, and the seat can be adjusted in the inclination direction of a leg placing plate in the calcaneus bone mineral density instrument. The front end of the seat face of the seat extends towards the calcaneus bone densitometer to form a supporting plate, and the supporting plate and the leg placing plate are parallel to each other and are arranged in an aligned mode. The bone mineral density ultrasonic detection device is convenient to use, the shanks can be just naturally attached to the supporting plate by adjusting the front-back position of a detected person on the seat surface, and due to the fact that the supporting plate is just aligned with a leg placing plate on the calcaneus bone mineral density instrument, the soles of the detected person can be tightly attached to a foot placing plate by adjusting the height of the seat, and the detection accuracy is improved. Therefore, the feet of the detector can be stably placed, and the problem that the detection result is inaccurate due to the fact that the detector exerts improper force and the feet are placed incorrectly is solved.

This invention relates to a bone mineral density measurement system and method. The system includes a CT scanner with a quantitative computed tomography (QCT) module, an independent single-calibration phantom, and a QCT data image processing program. The devices can exchange data via network or mobile storage. The data receiving module of the QCT data image processing program receives medical digital images from the CT scanner and measures the patient's bone mineral density through the bone mineral density analysis module. This invention combines a CT scanner, QCT, and a single-calibration phantom, employing an asynchronous scanning method that separates the phantom and the patient. This results in higher measurement accuracy, greater convenience, and improved patient comfort.

An implant type or a process of implant fixation is automatically identified by processing surgical plan information. Further, bone mineral density information associated with a patient is determined by processing at least one image. The determined bone mineral density information and patient information representing at least demographics associated with the patient are processed, and a selection of a plurality of patients that previously underwent arthroplasty is made. Outcome information representing results of arthroplasty procedures is processed and a threshold is established representing a biomechanical tolerance. The bone mineral density information is processed to be determined associated with the patient is determined to be above or below the threshold.

Disclosed herein is a method for manufacturing a composition promoting bone density enhancement, the method including preparing a mixture of Angelica gigas, Cnidium officinale, Phlomis umbrosa, Astragalus membranceus, Amomi fructus, Citri unshius pericarpium, Drynariae rhizoma, Codonopsis pilosulae radix, frankincense, and myrrh, aging the mixture, drying the mixture and grinding the dried mixture into a powder, and extracting a liquid from the powder.

The invention discloses a multi-mode ultrasonic coupling analysis system for measuring bone mineral density. The system comprises a shell, a foot placing groove, a sole supporting plate, a display screen, a first transducer, a second transducer, a clamping mechanism and a signal collecting and processing module, wherein the first transducer and the second transducer are oppositely arranged. A detachable double-state coupling piece is installed at the front end of the transducer, the coupling piece is provided with a first coupling face and a second coupling face which are equal in thickness but different in acoustic impedance, and the first coupling face and the second coupling face make contact with the skin in sequence when used. The device carries out bidirectional transmission measurement under multiple frequencies, the processing module averagely extracts transmission frequency dispersion characteristics through two-state difference and reciprocity, the center frequency, sharpness and sensitivity of a transmission window are obtained through fitting, and cortical-spongy transmission window indexes are formed and used for distinguishing osteoporosis phenotypes and longitudinal follow-up visit. According to the method, a traditional homogeneous model that QUS only depends on sound velocity and attenuation is broken through, frequency dispersion window characteristics of a cortical-cancellous double-layer structure are introduced into clinical quantitative indexes for the first time, and sensitivity to early osteoporosis and follow-up visit reliability are improved.

An ultrasonic radio frequency signal-based bone density prediction method and apparatus, and an artificial intelligence ultrasonic bone density meter. The bone density prediction method comprises: acquiring detection data of a tested user, the detection data comprising ultrasonic radio frequency signal data collected by a quantitative ultrasonic device from the tested user (S101); and on the basis of the detection data, using a trained bone density prediction model to perform bone density prediction on the tested user, wherein the bone density prediction model is obtained by training using multiple sample data collected from a plurality of subjects and respective labels of the multiple sample data; the bone density prediction model comprises an output layer and one or a plurality of multi-scale attention convolution channels; each multi-scale attention convolution channel comprises a cross-attention module and a plurality of convolution layers, wherein the plurality of convolution layers have different convolution kernel sizes for extracting multi-scale temporal features from the ultrasonic radio frequency signal data, and the cross-attention module is configured to perform weighted fusion of the multi-scale temporal features to obtain a fused feature map; and the output layer is configured to obtain a bone density prediction result on the basis of the fused feature map (S102).

The invention relates to fermented milk containing human milk oligosaccharide 2-FL and having a bone mineral density improving function. The invention provides application of human milk oligosaccharide 2-FL in preparation of a composition for improving bone health, and further provides a composition which contains the human milk oligosaccharide 2-FL and has a function of improving bone health. The composition comprises human milk oligosaccharide 2-FL and a leavening agent, wherein the leavening agent is one or a mixture of more of streptococcus thermophilus, lactobacillus bulgaricus and a vitamin K2-producing leavening agent. Compared with other technical schemes of the same type for enhancing the bone mineral density, the calcium intake of a subject is not additionally increased, the risk that the subject suffers from organ calculi is reduced, the application range is wider, and the preparation method is suitable for being applied to various fermented milk products.

The application discloses a dual-energy ray bone density evaluation method based on a flat panel detector and relates to the technical field of ray evaluation.The direct conversion mode of the flat panel detector is used to realize high-precision collection of low-energy and high-energy ray images, and noise and resolution loss caused by traditional indirect imaging are significantly reduced;one-time and two-time corrections are completed in an edge computing node, the problem of gray scale discontinuity and energy ratio distortion in the joint area of bones and soft tissues is effectively solved, and the authenticity of the image boundary is improved;further dynamic smoothing processing of the energy ratio is combined to obtain a stable ratio image, the stability and repeatability of bone density measurement are significantly enhanced, and more accurate bone density evaluation is realized.

The present invention relates to a system and a method for bone fracture risk assessment and provides for a system to predict Osteoporosis and Osteopenia and its associated fracture risk automatically from conventional chest X-ray image. The invention provides an automated digital X-ray bilateral Clavicle Radiogrammetry and its estimation of Cortical Thickness and Calculation of Cortical bone mass indices of Clavicle to predict dual Hips (Neck) Bone Mineral Density (BMD), dual Hips (Total) Bone Mineral Density (BMD) and Spine (Total) Bone Mineral Density (BMD) as measured by dual energy X-ray absorptiometry (DXA) bone densitometer and 10-year probability of both Major Bones (hip, spine, humerus or forearm)—and Hip-Osteoporotic Fracture Risk Scores. Using the same chest X-ray, an automated prediction of Osteoporosis and Osteopenia at both dual hips and spine regions and 10-year probability of both Major Bones and Hip Osteoporotic Fracture Risk using Artificial Intelligence (AI).

The invention discloses an osteoporosis pre-examination method based on multi-modal grading characteristics. The method comprises the steps that multi-source heterogeneous information such as bone mineral density, bone metabolism indexes, bone imaging and clinical medical history is collected, and the characteristics are extracted; inputting each modal feature into a depth potential space fusion model, and obtaining a preliminary fusion feature through mapping conversion and weight adjustment; inputting a cross-modal deep belief network for processing to obtain deep fusion features; and inputting an osteoporosis dynamic time sequence risk prediction model, outputting a risk time sequence prediction result in combination with historical time sequence features, and generating a pre-examination report containing risk indexes and feature contribution degrees. According to the method, through multi-model cooperation, deep fusion of multi-modal features, mining of deep association and combination of dynamic time sequence analysis, the defects that an existing method is poor in fusion effect and neglects time sequence changes are overcome, the pre-detection accuracy and the early warning capacity are improved, and a basis is provided for clinical decision making.

The invention belongs to the technical field of cartilage extracts, and particularly relates to application of a salmon nasal cartilage extract in preparation of a product for improving bone mineral density. The preparation method of the extract comprises the following steps: 1) performing low-temperature extraction on salmon nasal cartilage homogenate by using guanidine hydrochloride, centrifuging, and dialyzing to intercept total protein with the molecular weight of more than 8000; 2) adding precooled acetone into the total protein for fractional precipitation, and freeze-drying to obtain fractional precipitation protein; 3) dissolving the fractional precipitation protein in diluted hydrochloric acid, adding trypsin, and carrying out light-shielding enzymolysis to obtain an enzymatic hydrolysate; and (4) carrying out hydroxyapatite ion chromatography on the enzymatic hydrolysate, and carrying out ultrafiltration to intercept components with the molecular weight of less than 3kDa, so as to obtain the salmon nasal cartilage extract. The extract can significantly improve the multiplication capacity of embryo osteogenesis cell strains, can improve the bone mineral density value of shin bones of SD rats, has wide application prospects in the fields of food, health care products and medicines, and is especially suitable for development of bone health related products.

A method includes receiving preoperative or intraoperative data from an imaging system, receiving interoperatively stereotactic information during a surgical tool tracking from a navigational device, the navigation device configured to identify, confirm, project a location and display the surgical tool within a body, the navigational device further configured to process and interpret volumetric data and the stereotactic information to access a patient's local bone density within and without a current course and directional vector to assist a surgeon to decide on a size and material of an implant to be placed within a patient's bone.

1. The name of the design product: dual-energy X-ray bone densitometer (INNO S). 2. The use of the design product: for measuring the bone density and bone mineral content of human skeleton. 3. The design points of the design product: in shape. 4. The picture or photo that best indicates the design points: perspective view 1.

The application relates to a nail path determination method and device of a medical screw, a computer device and a storage medium. The method comprises the following steps: acquiring a candidate nail path of a medical screw in a target model of a target part; the target model is obtained according to a medical image of the target part; determining the distance between the candidate nail path and the surface of the target model and the image parameters of the candidate nail path in the medical image; the image parameters are used for characterizing the bone density of the target part; and determining the target nail path of the medical screw from the candidate nail path according to the distance and the image parameters. By using the method, the nail path with good safety and stability can be automatically determined, and the problem of time and labor consumption caused by manual marking is solved.

The invention provides a bone collagen peptide for increasing bone mineral density and a preparation method thereof, the method comprises the following steps: S1, dispersing bone gelatin in water to obtain a bone gelatin solution; s2, adding a 0.1-1 mol / L acidic pH regulator into the bone gelatin solution at a speed of 1-10 mL / min until the turbidity of the system is increased by 10-20% compared with the turbidity of the initial bone gelatin solution, then stopping adding, standing for 10-30 min, and filtering to obtain a bone gelatin supernatant; s3, adding endoprotease into the bone gelatin supernate to obtain enzymatic hydrolysate; and S4, performing post-treatment and drying on the enzymatic hydrolysate to obtain the bone collagen peptide. According to the method, the mass ratio of the low-molecular-weight polypeptide in the obtained bone collagen peptide can be increased, and the composition of the obtained bone collagen peptide is more suitable for bone metabolism to increase the bone density.

The invention discloses a bone mineral density measuring system and method.The bone mineral density measuring system comprises a support module, an X-ray generating module, a detector module and a processing module.The support module is used for carrying a host to move to a target position; the X-ray generation module adopts a PWM mode to control a high-voltage generator to carry out high-low voltage switching, the voltage and current of an X-ray tube are adjusted, X-rays are rapidly output, and the X-rays irradiate and penetrate through the forearm of a patient. According to the bone mineral density measuring system and method, the PWM control high-low energy X-ray rapid switching technology and the large-size detector are adopted, so that the detector can synchronously capture the attenuation difference of the bone to different energy rays in single scanning, the imaging time is shortened, full coverage of a key area at the far end of the forearm is ensured, and the accuracy of bone mineral density measurement is improved. The image resolution and the micro-structure capturing capacity are improved, meanwhile, positioning errors caused by forearm positioning deviation or shaking during shooting are eliminated, and the accuracy and reliability of diagnosis results are improved.

The present invention relates to a composition for treating osteoarthritis, the composition containing an herbal medicine extract as an active ingredient. It was found that an herbal medicine complex extract according to the present invention improves an arthritis index and increases bone mineral mass and bone density in an osteoarthritis animal model. In addition, it was found that the herbal medicine complex extract prevents cartilage damage, thereby increasing the thickness of cartilage, and regulates the expression of tissue regeneration factors and inflammatory cytokines.

The invention belongs to the technical field of medicines, and particularly relates to a plant microcapsule for improving bone mineral density and a preparation method and application thereof. The plant microcapsule for improving the bone mineral density is composed of a content and a soft capsule shell, and the content is prepared from, by mass, 1.5-2.2 parts of vitamin D, 15-20 parts of nude fern herb, 5-10 parts of caulis spatholobi, 12-18 parts of radix clematidis, 10-15 parts of eucommia ulmoides, 10-15 parts of radix dipsaci, 6-12 parts of angelica sinensis, 4-12 parts of ligusticum wallichii, 6-11 parts of salvia miltiorrhiza, 7-13 parts of cassia twigs, 10-15 parts of radix achyranthis bidentatae, 18-22 parts of coix seeds and 1-5 parts of liquorice. And 80-90 parts of grape seed oil. The plant microcapsule for improving the bone mineral density can effectively improve the bone mineral density, and is high in stability and convenient to store.

The invention relates to the technical field of health risk assessment, in particular to a postmenopausal osteoporosis risk prediction and traditional Chinese and western medicine intervention management system. The system quantifies the trend risk of the bone mineral density through the deviation change of the bone mineral density risk value in time sequence, and combines the initial bone mineral density risk to divide the group and analyze and identify the risk degree of the group; coupling the drop fluctuation characteristics of hormones with the change of bone metabolism markers to obtain the comprehensive metabolic risk influence degree; determining the comprehensive influence degree of osteoporosis by utilizing the group comprehensive bone mineral density risk degree dynamic adjustment and combining the external risk influence degree and the comprehensive metabolic risk influence degree; and based on the osteoporosis comprehensive influence degree of the sample data, training a neural network model to carry out risk prediction. According to the method, the risk model is constructed by considering the multi-dimensional influence of hormone metabolism and behavioral habits of the postmenopausal patient and the multi-dimensional coupling evaluation value, so that the risk prediction accuracy is improved, and more comprehensive and reliable data support is provided for bone health management of postmenopausal women.

This invention discloses a multi-objective optimization-based method for preoperative tibial prosthesis localization in ankle replacement surgery, primarily addressing the problems of poor accuracy and low reliability in existing ankle prosthesis localization methods. The method includes: 1) acquiring and processing medical CT images and prosthesis model data of the affected lower limb, completing prosthesis standard position calibration and establishing a local coordinate system; 2) segmenting bone tissue, extracting three-dimensional models of the tibia, fibula, and talus, and including HU bone mineral density values; 3) standardizing the skeletal model, labeling anatomical landmarks, and constructing an orthogonal standard coordinate system; 4) pre-calculating relevant data of the distal tibial articular surface; 5) generating initial candidate solutions through grid search and constraint filtering; 6) obtaining the Pareto front by combining the NSGA-II-CDP algorithm and constraint dominance principles; 7) recommending the optimal solution and generating a visual model through multi-stage compromise solution filtering and multi-criteria decision-making. This invention can unify anatomical orientation, improve computational efficiency, and achieve accurate and efficient localization.

This invention relates to the application of SRGN in the treatment and diagnosis of osteoporosis, belonging to the field of biomedical technology. This invention reveals for the first time the key role of SRGN in the pathogenesis of osteoporosis, suggesting its potential as a novel therapeutic or diagnostic target for osteoporosis. Furthermore, this invention designs a novel neutralizing antibody against SRGN, 12E2, which effectively blocks the interaction between SRGN and SIGLEC15, showing significant inhibitory effects on osteoclast formation in both in vivo and in vitro models. In animal experiments, SRGN neutralizing antibody 12E2 or... Srgn Knockout significantly improved bone mineral density in mice. This invention provides novel molecular targets and strategies for the treatment or diagnosis of osteoporosis, and has promising clinical application prospects.

Disclosed is the use of dithiocarbamate compounds in the preparation of a drug for preventing and / or treating osteoporosis. The dithiocarbamate compounds can effectively prevent and / or treat osteoporosis, improve bone mineral density in patients with osteoporosis, and reduce the risk of fractures. Moreover, the dithiocarbamate compounds, when used in combination with a calcium supplement, can achieve better preventive and / or therapeutic effects on osteoporosis.

1. The name of the design product: set of fitness equipment. 2. The use of the design product: for strengthening bone density fitness. 3. The design points of the design product: in the combination of shape and color. 4. The picture or photo that best shows the design points: perspective view. 5. The design claimed contains color.

The invention provides a preparation method, device and equipment of a percutaneous channel internal fixing screw, a medium and a product. The method comprises the following steps: acquiring three-dimensional image data of a target object, wherein the three-dimensional image data comprises a region of interest of a to-be-implanted internal fixation screw; recognizing a screw implantation channel based on the three-dimensional image data, and recognizing bone mineral density data corresponding to the screw implantation channel; based on the bone mineral density data of the screw implantation channel and a pre-constructed screw preparation parameter selection model, determining internal fixation screw parameters suitable for the target object; and screw printing processing is carried out based on the internal fixation screw parameters, and the internal fixation screw suitable for the target object is obtained. According to the technical scheme, the adaptation degree of the internal fixation screw and the bone is improved, the stress shielding rate is effectively reduced, and individualized adaptation of the internal fixation screw is achieved.

The invention belongs to the technical field of propaganda and education, and discloses an immersive propaganda and education system and a use method, and the system comprises an oral data collection device which is used for collecting intraoral three-dimensional geometric data and intraoral bone mineral density data; the MR visual presentation equipment is used for displaying an optical fusion scene of a virtual operation scene and a real environment and collecting user pose data; the tactile feedback interaction equipment is used for simulating the operation tactile sense of the dental implant surgery and collecting hand action data; the core operation and communication device constructs a three-in-one immersive interaction system by fusing MR vision, touch simulation and 3D spatial sound effects, and realizes accurate simulation and immersive experience of the whole process of an operation in combination with personalized oral data of a patient, so that preoperative anxiety of the patient is effectively relieved, and propaganda and education effects are improved.

The invention discloses a bone mineral density estimation method based on neural network memory attention and multi-scale smoothing, which is characterized in that 3D spatial features are accurately captured by introducing a neural memory attention mechanism, and the problem of serious unbalanced distribution in clinical data is solved by combining a multi-scale adaptive label distribution smoothing technology and a feature distribution smoothing technology. Therefore, high-precision bone mineral density prediction can be realized from the conventional CT image without extra DXA scanning.