247 results about "Bone mass density" patented technology

The present invention relates to antibodies against sclerostin and compositions and methods of use for said antibodies to treat disease related to bone abnormalities such as osteoporosis. An embodiment of the invention herein provides an antibody or a functional protein comprising an antigen-binding portion of said antibody for a target in sclerostin polypeptide, characterized in that the antibody or functional protein specifically binds to sclerostin polypeptide and can increase at least one of bone formation, bone mineral density, bone mineral content, bone mass, bone quality and bone strength in a mammal.

The invention relates to health food for enhancing human immunity and increasing bone mineral density and a preparation method thereof; the health food of the invention comprises the following components: hyaluronic acid, glucosamine, collagen, kudzu root extracts, chondroitin sulfate, vitamins, calcium, etc; because of the embedding processing of hyaluronic acid, the defect of property change of hyaluronic acid due to moisture absorption and influence of environmental factors is overcome; the health food prepared by the organic combination of the embedded hyaluronic acid with glucosamine, collagen, plant extracts, vitamins, mineral matter and the like has functions and effects which can supplement each other, has the effects of lubricating joints, increasing bone mineral density, and enhancing bone strength during long-term administration, and also has the functions of delaying aging, removing freckles and beautifying faces, and the like; the health food of the invention can be prepared into powder, granules, tablets, capsules, is convenient for carrying and taking, has stable and lasting efficacy, has no side effects, and is an ideal health food of patients with hypoimmunity and osteoporosis.

The present invention relates to methods for prevention and/or treatment of metabolic disorders, post-menopausal obesity and conditions associated with high fat diet consumption including, obesity, body weight gain, fat mass formation, bone mineral content reduction, white adipose tissue weight gain, increased cholesterol levels, increased leptin levels, insulin resistance, type II diabetes, increased blood glucose levels, inflammatory diseases, cardiovascular diseases, fatty liver condition (accumulation of fat in the liver), decreased uncoupling protein-1 (UCP-1) levels and increased lipogenesis.

The invention belongs to the field of sports research, in particular to a scientific fitness guidance system. The system realizes the collection on the basic information of human bodies, test on comprehensive sports ability and comprehensive analysis and evaluation on conditions of body functions. The system comprises a total control analytic host machine which is respectively connected with a body composition tester, a balance capacity tester, a bone mineral density tester, a flexibility tester, a physical strength tester, a maximal oxygen uptake tester and a reaction time tester through a local area network; the contribution of the scientific fitness guidance system to the prior art is to simply and rapidly provide comprehensive human body experiment test data for establishing a test program and method of sports function of adults and an evaluation method of comprehensive sports ability and constructing a scientific sports fitness evaluation and guidance system of Chinese citizens; the scientific fitness guide system realizes one-time test on the comprehensive data of human bodies and can rapidly and accurately carry out the comprehensive analysis and evaluation on physical conditions by setting threshold values to finish the formulation of a personalized sports fitness guidance scheme.

The invention relates to a bone mineral density increase health capsule and a preparation method thereof. The capsule is composed of a capsule body and a content closed in the capsule body. The content is characterized in that the content comprises 15-30wt% of calcium carbonate, 8-20wt% of chondroitin sulfate, 10-25wt% of D-glucosamine hydrochloride, 0.02-0.2wt% of vitamin K1, 10-20wt% of a collagen polypeptide, 5-15wt% of momordica saponin, 5-15wt% of soybean isoflavone, 5-20wt% of sheep bone marrow peptide powder, 0.1-0.5wt% of vitamin D3 and 0.5-1wt% of an auxiliary material magnesium stearate; and the preparation method comprises the following steps: uniformly stirring the content, sending the uniformly stirred content to a capsule filling machine for filling the content to capsule shells, polishing, choosing, and packaging to obtain the bone mineral density increase health capsule. The health capsule has the advantages of synergistic effect of the above components, common improvement of the absorption of calcium by human bodies, bone mineral density increase, safety, reliability, obvious effect, and carrying and administrating convenience. The preparation method of the health capsule has the advantages of reasonable technology and strong operability.

The invention provides a composition with effects of protecting joints and increasing bone mineral density. The composition is prepared from the following components in parts by weight: 250-400 parts of calcium citrate malate, 150-300 parts of N-Sulfo-glucosamine potassium salt, 100-200 parts of chondroitin sulfate, 50-150 parts of bone collagen peptide powder, and 10-50 parts of casein phosphopeptides. According to the composition provided by the invention, the active ingredients achieve the synergistic effect, the bioavailability is high, and the composition can be used for increasing the bone mineral density and restoring the bone functions. Through a preparation method provided by the invention, the composition can be prepared into a compound preparation, the curative effects are definite, the quality is controllable, no toxic or side effect exists, and the composition is suitable for large-scale popularization and application.

The invention provides a composition for increasing the bone mineral density. The composition mainly comprises the following raw materials in parts by weight: 180-540 percent of calcium carbonate, 23-69 percent of D-glucosamine hydrochloride and 15-45 percent of collagen. The invention also provides a preparation method of the composition. The raw materials adopted by the composition for increasing the bone mineral density have no toxic and side effects, health and safety, has the effects of promoting calcium absorption and relieving osteoporosis and can safely and effectively supplement calcium of the human body and ensure that the calcium level is improved so as to prevent fractures and bone loss and has improvement effect on bone formation. Moreover, the invention adopts scientific andreasonable production process and better retains active constituents in various raw materials.

The present invention relates to a nutritional composition for infants and/or toddlers comprising a lipid component which has a lipid globules coated with phospholipids. The composition is used for increasing bone mineral content, bone mineral density, preventing osteoporosis, and/or preventing ostopenia.

The invention provides a method for extracting artemisinin. The artemisinin is prepared through the method of supercritical fluid extraction and the method of microwave-assisted extraction, and the content of the artemisinin is greatly improved. The invention further provides the application of the artemisinin in preparing medicines for inhibiting proliferation of rat adrenal gland pheochromocytoma cell PC-12 and the application of the artemisnin in preparing medicines for increasing bone mineral density.

The invention relates to a computer aided detection and remote consultation system of bone mineral density. A bone mineral density computed tomography (CT) measuring method can selectively measure the cancellous bone density and is a blank in telemedicine. The system comprises a terminal ordering system, a terminal preprocessing system, a cloud computing processing center and a hospital backstage service management system. The terminal ordering system comprises a patient ordering module, wherein the patient ordering module is connected with a doctor calling module and a calling terminal. The terminal preprocessing module comprises a CT shooting device, a medical image processing system, a data remote transmission system and a terminal printing system. The cloud computing processing center comprises an image sorting, encrypting and decrypting processing module, a computer aided detection system and an expert outpatient service system. The hospital backstage service management system comprises an inquiring or storing case of illness image data bank and a diagnosis work station. The computer aided detection and remote consultation system of the bone mineral density can aim at the bone mineral density CT measurement to carry out consultation of doctors in different places, filter noise when the teletransmission is carried out on primary information, and break geographic restrictions. The patient can get more authoritative treatment.

The invention discloses a composition for increasing bone mineral density and a preparation method of the composition. Chinese dwarf cherry, a Chinese herbal medicine extract refined by a modern extraction technology and other raw materials with the function of increasing the bone mineral density are scientifically compounded, are scientifically combined in an omnibearing manner, and work together, so as to achieve the effects of effectively promoting absorption of calcium from a plurality of aspects, restoring and rebuilding cartilago articularis, creating synovial fluid, and promoting collagen synthesis in the cartilago articularis, preventing cartilage from further degenerating, indirectly reducing osteoclast action, inhibiting re-absorption of bones, increasing bone calcium content and improving the mechanical property of the bone, so that the product has a good effect of increasing the bone mineral density. The integrating property and the biological stability of the composition can be further improved by a microwave drying technology in the preparation method. Due to the oxidation resistance of a grape pip extract in the raw materials, high adsorption and embedding effects of modified dietary fiber, and antifungal properties of the Chinese herbal medicine extract, the efficient, safe, nutrient and stable composition with the function of increasing the bone mineral density is finally prepared.

The embodiment of the invention discloses a centrum mechanical strength evaluation method and device, computer equipment and a storage medium. The method comprises the following steps: acquiring CT image data of a vertebral body; extracting a single segment of the vertebral body from the CT image data of the vertebral body as a to-be-evaluated vertebral body to carry out three-dimensional construction so as to obtain a three-dimensional structure of the to-be-evaluated vertebral body; carrying out discrete processing on the three-dimensional structure of the to-be-evaluated vertebral body to obtain a plurality of discrete unit bodies; adding discrete unit bodies used for representing splints to the upper surface and the lower surface of the to-be-evaluated vertebral body; carrying out material attribute description on the discrete unit bodies to endow the discrete unit bodies with corresponding bone mineral density, Young modulus and Poisson's ratio; applying boundary conditions and constraint conditions to the discrete unit bodies used for representing the clamping plates, and establishing a stress and strain relation equation set of the to-be-evaluated vertebral body according to the material attributes of the discrete unit bodies; and based on the stress and strain relation equation set of the to-be-evaluated cone, evaluating the to-be-evaluated cone under a preset load to obtain the mechanical strength of the to-be-evaluated cone.

The invention relates to a nail path planning method and apparatus of a bone screw. The method comprises the following steps: 1) establishing an individual three-dimensional geometric model of a target bone, and a three-dimensional bone density model containing spatial distribution information of bone density; 2) setting bone screw parameters, and calculating the space vector of a bone screw axis;3) calculating a space helical line of bone threads as a bone screw thread curve; and 4) placing the bone screw thread curve into the individual three-dimensional geometric model of the target bone,extracting the bone density at points of contact with bone screw threads in the individual three-dimensional geometric model of the target bone, and calculating an average value of the bone density atthe contact positions; and planning a bone screw nail path according to the bone screw parameters, the bone density and the distribution of the bone density. According to the method, by obtaining coordinates of the bone and bone screw contact positions on the three-dimensional scale, the bone density around the screw threads is determined accurately and meticulously, and an optimal nail path of the bone screw is determined according to the fixation performance of the bone screw.

The invention relates to the field of bone mineral density measurement, in particular to a bone mineral density measurement method and system, a storage medium and electronic equipment. The method comprises the following steps: step 1, carrying out spine area detection on a CT chest plain scanning sequence image through an optimized target detection algorithm to obtain a spine area image; step 2, inputting the spine region image into a spine segmentation model for segmentation to obtain a segmentation result; step 3, processing the segmentation result to obtain a cancellous bone region; and step 4, training a regression bone mineral density detection model based on the cancellous bone area, and inputting an image to be measured into the regression bone mineral density detection model to obtain a bone mineral density value. The method can achieve the effects of higher efficiency and higher accuracy.

The invention provides an ultrasonic apparatus for preventing osteolysis from appearing around a prosthesis after joint replacement. The ultrasonic apparatus is mainly composed of a processor, an ultrasonic generator, an output probe, a display screen, an operation rotary knob, a power supply and an ultrasonic apparatus shell, wherein the processor and the ultrasonic generator are located in the ultrasonic apparatus shell, the processor, the ultrasonic generator and the display screen are connected with the power supply in series, and the ultrasonic generator is connected with the output probe. The ultrasonic apparatus is reasonable in design and convenient to carry, the ultrasonic frequency, the strength, the duty ratio, the working hour span and the area of the output probe can all be adjusted and matched with data bases composed of different parameters combinations, different types of parameter setting can be arranged as required, probes in different sizes can be adopted as required, corresponding low-energy ultrasonic waves are transmitted to the area around the prosthesis, therefore, the osteolysis is prevented from appearing around the prosthesis, reconstruction of bone trabeculas around the prosthesis is promoted, the bone mineral density around the prosthesis is improved, the service life of the prosthesis is prolonged, the ultrasonic apparatus is suitable for different people, no use contraindication exists, no invasive intervention occurs to a user, and the ultrasonic apparatus is relatively safe.