The invention provides mixed sizing for preparing a manmade beef bone button. The mixed sizing comprises sizing A and sizing B. The sizing A comprises, by weight, 20-100 parts of unsaturated polyester resin, 5-50 parts of pigment, 0.2-2 parts of accelerant and 0.4-2 parts of initiator. The sizing B comprises, by weight, 800-1200 parts of unsaturated polyester resin, 1.0-8.0 parts of pigment, 5.0-50 parts of soluble fine granular packing, 5.0-80 parts of styrene, 2.0-20 parts of accelerant and 4.0-20 parts of initiator. The prepared manmade beef bone button is made of the unsaturated polyester resin material which is wide in source and low in price, the manmade beef bone button has the bone stripe texture and the bone age texture like natural beef bone buttons, and the stability is controllable after the button is dyed.