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Traditional Chinese medicine composition for treating cardiovascular diseases and preparation method thereof

A composition and cardiovascular technology, applied in the field of traditional Chinese medicine, can solve problems such as lack of effective drugs, and achieve the effects of abundant raw materials, scientific and reasonable formulations, and good effects

Pending Publication Date: 2020-06-19
THE CHINESE TRADITIONAL HERB MEDICINE RES INST HENAN PROV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, there is still a lack of effective drugs for the treatment of this disease with traditional Chinese medicine, and clinical research and development are urgently needed

Method used

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  • Traditional Chinese medicine composition for treating cardiovascular diseases and preparation method thereof
  • Traditional Chinese medicine composition for treating cardiovascular diseases and preparation method thereof
  • Traditional Chinese medicine composition for treating cardiovascular diseases and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0040] Example 1 Chinese medicine preparation "Shenlou Tablet"

[0041] This embodiment provides a traditional Chinese medicine preparation "Shenlou Tablet" for treating coronary heart disease with carotid atherosclerotic plaque, which is a tablet, 0.3 grams per tablet, which is equivalent to 0.6 grams of decoction pieces. It includes the following components by mass: 12 parts of ginseng, 15 parts of Trichosanthes bark, 3 parts of Panax notoginseng, 3 parts of leech, 20 parts of hawthorn, 20 parts of cassia seed, 6 parts of red yeast rice, and an appropriate amount of auxiliary material starch essence dextrose.

Embodiment 2

[0042] The preparation method of embodiment 2 Chinese medicine preparation " Shenlou tablet "

[0043] This embodiment provides the preparation method of the traditional Chinese medicine preparation of embodiment 1, comprising the following steps:

[0044] (1) Crushing: According to the mass parts, weigh 12 parts of ginseng, 15 parts of Trichosanthes bark, 3 parts of Panax notoginseng, 3 parts of leech, 20 parts of hawthorn, 20 parts of cassia seed, and 6 parts of red yeast rice. Dry them and put them into a pulverizer together for crushing;

[0045] (2) Extraction: Add 50% ethanol solution with a mass ratio of 6-10 times the mass to the pulverized powder in step (1) and then ultrasonicate for 25-35min; 50-65°C, collect the extract, add 50% ethanol to immerse the dregs, extract for 0.8-1.2h in a water bath reflux for the second time, collect the extract, add 50% ethanol to immerse the dregs, and use it for the third time Extract in water bath reflux for 0.8-1.2h, extract 3 t...

Embodiment 3

[0050] Clinical Application of Example 3 Chinese Medicine Preparation "Shenlou Tablet"

[0051] 1. Clinical data

[0052] 1.1 General information

[0053] From January 2018 to January 2019, 100 patients with definite coronary heart disease and carotid atherosclerotic plaque confirmed by cervical color Doppler who were hospitalized in the applicant's geriatric department were randomly divided into two groups according to the sequence of hospitalization. Treatment group and control group.

[0054] Among the 50 cases in the treatment group, there were 26 males and 24 females; the age ranged from 42 to 75 years, with an average of (64.00±12.06) years old. In the control group, there were 23 males and 27 females; aged 40 to 75 years, with an average of (63.00±12.15) years old. There was no statistically significant difference between the two groups in terms of gender, age, course of disease and other basic information (P>0.05), and they were comparable.

[0055] 1.2 Diagnostic ...

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Abstract

The invention discloses a traditional Chinese medicine composition for treating cardiovascular diseases, and particularly for treating coronary heart diseases with carotid atherosclerotic plaques, andbelongs to the field of traditional Chinese medicines. The traditional Chinese medicine composition comprises the following components in parts by mass: 8-15 parts of ginseng roots, 10-20 parts of snakegourd peel, 1-5 parts of pseudo-ginseng roots, 1-5 parts of leech, 10-30 parts of hawthorn fruits, 10-30 parts of cassia seeds and 5-8 parts of red rice. The invention also discloses a preparationmethod of the traditional Chinese medicine composition, and the preparation method comprises the steps of crushing, extracting, concentrating and drying, granulating, wet granule drying and tabletting. The traditional Chinese medicine composition provided by the invention has obvious effects on qi deficiency and blood stasis type coronary heart diseases, angina pectoris, hyperlipidemia accompaniedwith carotid atherosclerosis plaque and the like, has a definite medicinal effect, and can stabilize and reduce arteriosclerosis plaque after being taken for a long time.

Description

technical field [0001] The present invention relates to the field of traditional Chinese medicine, in particular, to a traditional Chinese medicine composition for treating cardiovascular disease and a preparation method thereof, more specifically, to a traditional Chinese medicine composition for treating coronary heart disease combined with carotid atherosclerotic plaque and its preparation method. Preparation. Background technique [0002] With the rapid changes in people's diet structure and lifestyle and the aging of the population, the incidence of coronary heart disease is increasing year by year, and patients with coronary heart disease combined with carotid atherosclerotic plaques are gradually being clinically concerned as a high-risk group. Related studies have shown that there is a close relationship between coronary heart disease and carotid atherosclerosis. About 42.3% to 65.3% of patients with coronary heart disease have carotid atherosclerotic plaques detecte...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/899A61K36/734A61K9/20A61P9/10A61K35/62
CPCA61K9/2059A61K35/62A61K36/062A61K36/258A61K36/428A61K36/482A61K36/734A61K36/899A61K2236/19A61K2236/333A61K2236/39A61P9/10A61K2300/00
Inventor 杨辰华
Owner THE CHINESE TRADITIONAL HERB MEDICINE RES INST HENAN PROV
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