109results about How to "Solving Medication Problems" patented technology

The invention relates to a preparation method and application of hyaluronic acid modified by vitamin E succinate and is capable of effectively solving the problems of preparation of hyaluronic acid modified by vitamin E succinate and the application in antitumor drugs. The preparation method comprises the following steps: with alkylidene diamine or dithio alkylidene diamine as a linking arm, hyaluronic acid is covalently linked to vitamin E succinate according to the weight ratio of 1:(1-100) so as to form a nano-micelle in a water medium, wherein hyaluronic acid is low-molecular-weight hyaluronic acid with the molecular weight no less than 600 daltons and no larger than 400kd; the linking arm is the alkylidene diamine or the dithio alkylidene diamine with the amount of carbon atoms being 2-12, and a disulfide bond in the dithio alkylidene diamine has the oxidation-reduction sensitivity in vivo and is capable of releasing the antitumor drugs in a targeting mode in tumor cells. With HA as a skeleton, hyaluronic acid modified by vitamin E succinate is high in drug loading capacity and easy in releasing of the drugs, is effectively used for preparing the antitumor drugs, is capable of solving the problem of medication for treating tumors and is an innovation of the drugs for treating the tumors.

A fast dispersing solid Chinese medicine for restoring health is prepared from 13 Chinese-medicinal materials including cablin potchouli herb, perilla leaf, tangerine peel, liquorice root, etc through crushing or extracting, superfine pulverizing, and mixing with disintegrant, adhesive, suspending aid, flowing aid, flavouring and coloring agent.

The invention relates to a fullerene-nanogold composite material as well as a preparation method and application thereof and aims at effectively solving the problems of preparation of the fullerene-nanogold composite material and application of the fullerene-nanogold composite material serving as a radio-frequency or microfiltration irradiation medicament in tumor in-situ advanced photothermal therapy. The preparation method comprises the following steps of: dissolving a fullerene amination derivative in an organic solvent A, adding sodium hydride, uniformly stirring, adding bromomalonic acid diethyl ester, removing the sodium hydride and the organic solvent A, and carrying out vacuum drying to obtain fullerene substituted by the bromomalonic acid diethyl ester; adding the fullerene substituted by the bromomalonic acid diethyl ester and the sodium hydride into the organic solvent A, magnetically stirring until the mixture colorless, removing the organic solvent A, adding concentrated hydrochloric acid, filtering to obtain a filter cake, dissolving the filter cake in methanol, removing undissolved substances, carrying out rotary evaporation to remove the methanol, and carrying out vacuum drying to obtain a fullerene carboxylation derivative; adding the fullerene carboxylation derivative into a chloroauric acid water solution, then adding a solution B, ethanol or acetone, filtering to obtain a filter cake, washing the filter cake by using ethanol or acetone, and carrying out vacuum drying to obtain the fullerene-nanogold composite material. The preparation method is easy to operation; the fullerene-nanogold composite material has a good effect and is an innovation of antitumor medicaments.

The Chinese medicine powder for treating nasosinusitis as well as rhinitis, chronic rhinitis, erosive nasal septum is prepared with 18 kinds of Chinese medicinal materials including thunberg fritillary bulb, Chuanxiong rhizome, glabrousleaf pittosporum seed, flavescent sophora root, dahurian angelica root, etc. which are produced into medicine powder and capsulized. The medicine has high curative effect and no toxic side effect.

A fast dispersing solid Chinese medicine for clearing stomach is prepared from 24 Chinese-medicinal materials including rhubarb, coptis root, haw, tangerine peel etc through crushing or extracting, superfine pulverizing, and mixing with disintegrant, adhesive, suspending aid, flowing aid, flavouring and coloring agent.

A fast dispersing solid Chinese medicine forwarming uterus is prepared from 10 Chinese-medicinal materials including cinnamon bark, Chinese angelica root, Chuan-xiong rhizome, white peony root, etc through crushing or extracting, superfine pulverizing, and mixing with disintegrant, adhesive, suspending aid, flowing aid, flavouring and coloring agent.

The invention discloses a medicine for eliminating phlegm and stopping cough, relieving dyspepsia and activating blood and dissolving stasis and a preparation method thereof. The medicine is a sugarless seabuckthorn granule made up of a seabuckthorn extract (a solid matter), mannite, dextrine, soluble starch and steviosin. The medicine has advanced production technique, good drug effect, low dosage, and is convenient for taking and carrying. In addition, the medicine solves the problems on drug taking for patients with diabetes, obesity, cardiovascular diseases and decayed tooth, and obtains unexpected effects.

The invention relates to a traditional Chinese medicine for treating breast hyperplasia and breast cancer. The traditional Chinese medicine can be used for effectively solving the treatment medicinal problems of the breast hyperplasia and breast cancer. The technical scheme for solving the problems is as follows: the traditional Chinese medicine is prepared from radix curcumae processed with vinegar, trigone processed with vinegar, rhizoma zedoariae processed with vinegar, processed pangolin, seaweed, iphigenia indica, radix codonopsitis, astragalus root, fruit of glossy privet, honeysuckle, lithospermum, chrysanthemum, rhizoma cyper processed with vinegar, trichosanthes, rubia root, corydalis tuber processed with vinegar, uniflower swisscentaury root, rhizoma coptidis, processed vomiting nut, chilopod, rheum officinale, fried cowherb seed, fried mustard seed, tangerine seed, prepared frankincense, prepared myrrh, oarweed and paris polyphylla. The material medicines are crushed and prepared into pills by using water and dried, respectively. The material medicines are effectively combined and supported with each other to achieve the effects of detoxicating and resolving a mass, tonifying qi and dredging collaterals, and promoting blood circulation to remove blood stasis. Besides, the traditional Chinese medicine is effectively used for treating the breast hyperplasia and breast cancer, and is safe in medicine use, good in curative effect and innovative on medicines for treating the breast hyperplasia and breast cancer.

A fast dispersing solid Chinese medicine for invigorating the function of infantile spleen is prepared from 8 Chinese-medicinal materials including yam, chickení»s gizzard-skin, white atractylodes rhizome, tendrilled fritillary bulb, etc through crushing or extracting, superfine pulverizing, and mixing with disintegrant, adhesive, suspending aid, flowing aid, flavouring and coloring agent.

A fast dispersing solid Chinese medicine for clearing lung is prepared from 24 Chinese-medicinal materials including mulberry bark, honeysuckle flower, scutellaria root, liquorice root, etc through crushing or extracting, superfine pulverizing, and mixing with disintegrant, adhesive, suspending aid, flowing aid, flavouring and coloring agent.

The invention relates to a medicinal grease for relaxing vein and removing pain, and process for preparation, wherein the grease is prepared from Chinese angelica root, Ligusticum wallichii, safflower, Resurrectionlily rhizome, pricklyash peel, piper nigrum, clove, Cinnamomum cassia, long pepper, dried ginger, rhubarb horsetails, camphor, baras camphor and mentha-camphor through steps of disintegrating, impregnating with ethanol, carrying out diacolation, charging gasoline for abstraction, separating ethanol, obtaining extract oil, subjecting Cinnamomum cassia to ethanol diacolation, extracting with gasoline, percolating extracted medicinal dross with ethanol, collecting the percolation liquid, obtaining extract through decompression and concentration, making base material from rubber, colophony, Vaseline, fluid wax, zinc oxide, dimethyl sulfoxide and gasoline, charging concrete, extractive oil and camphor, mixing homogeneously and applying onto base fabrics.

A Chinese medicine in the form of plaster for treating bony arthritis is prepared from 9 Chinese-medicinal materials including Chinese angelic root, Chuanqiong rhizome, dried ginger, cinnamon bark, etc and the matrix prepared from rubber, rosin, zinc oxide, Vaseline, etc. Its preparing process is also disclosed.

The invention relates to a traditional Chinese medicine for treating premature ovarian failure. The traditional Chinese medicine can be used for effectively solving the problem of medication of premature ovarian failure. The technical scheme for solving the problem is as follows: the traditional Chinese medicine is prepared from the following raw medicinal materials in parts by weight: 5-20 parts of glossy privet fruit, 5-20 parts of barbary wolfberry fruit, 3-12 parts of donkey-hide glue, 5-25 parts of palmleaf raspberry fruit, 1-5 parts of dried human placenta, 3-10 parts of tokay, 5-15 parts of Chinese caterpillar fungus, 5-15 parts of turmeric root-tuber, 10-30 parts of akebia fruit, 5-20 parts of Chinese angelica, 10-20 parts of salvia miltiorrhiza and 3-10 parts of motherwort fruit. The traditional Chinese medicine provided by the invention is rich in raw material, low in price, scientific in composition and reasonable in compatibility, and the medicinal materials support one another and act together to achieve the effects of nourishing yin and blood, enriching kidney essence, soothing the liver and relieving depression, as well as nourishing blood and promoting blood circulation, so that the traditional Chinese medicine is good in curative effect and safe in medication when effectively used for treating the premature ovarian failure, and is a big innovation of medicaments for treating the premature ovarian failure.

A fast-dispersing Chinese medicine in the form of solid is prepared proportionally from motherwort, Chinese angelica root, Chuan-xiong rhizome and aucklandia root through crushing or extracting, superfine pulverizing, mixing with disintegrant, adhesive, suspending aid, flowing aid, flavouring and coloring agent, and conventional steps.

A fast dispersing solid medicine for strengthening middle energizer to nourish qi is prepared from 8 Chinese-medicinal materials including astragalus root, pilose asiabell root, liquorice root, Chinese angelica root, etc. Its preparing process is also disclosed.

A Chinese medicine in the form of fast dispersing solid is prepared from 8 Chinese-medicinal materials including anemarrhena rhizome, pellodendron bark, tree peony bark, yam, etc.

The invention relates to an oral ulcer healing membrane with traditional Chinese medicine bioadhesive one-way medicine release, capable of effectively solving the problem of used medicines for treating the oral ulcer. The technical scheme for solving the problem is as follows: the ulcer healing membrane is prepared by the following materials: 10-13g of figwortflower picrorhiza rhizome, 10-13g of tree peony bark, 8-11g of natural indigo, 1.5-2.5g of borneol, 2-4g of Carbomer 934P, 2-4g of hydroxy propyl cellulose, 2.3-2.5g of sodium cyclamate, 10-14ml of glycerin and ethyecellulose and absolute ethyl alcohol. The invention has reasonable compatibility of components, advanced and unique method, convenient use and good treatment effect and is innovation for treating oral ulcer.

The invention relates to an anti-tumor-metastasis Chinese medicament capable of effectively solving the problems of medication of anti-tumor metastasis. The technical scheme used for solving the problems is that the Chinese medicament is prepared from the following bulk medicaments in parts by weight: 10-30 parts of largehead atractylodes rhizome, 10-30 parts of white poria, 10-30 parts of catclaw buttercup, 10-30 parts of yangtao actinidia root, 10-30 parts of doederlein's spikemoss herb, 10-60 parts of hairyvein agrimonia herb and bud, 9-30 parts of fiveleaf gynostemma herb, 5-20 parts of Chinese trumpet creeper and 10-30 parts of Chinese sage herb. The Chinese medicament is prepared through the steps of firstly mixing the bulk medicaments together, adding water of which the weight is 8-10 times that of the bulk medicaments, soaking for 2-4 hours, decocting for 30-40 minutes, and filtering to obtain first filtrate; adding the water of which the weight is 8-10 times that of the bulk medicaments into medicament dregs again, decocting for 30-40 minutes, and filtering to obtain second filtrate; combining the filtrate of the two times. The Chinese medicament disclosed by the invention is abundant in raw materials, has the effects of detoxifying, resolving masses, invigorating the circulation of blood, tonifying qi and strengthening the spleen, is definite in curative effect and good in use effect, and provides an innovation for anti-tumor-metastasis medicaments.

The invention relates to a traditional Chinese medicine patch for treating cough and dyspnea, which can be used for effectively solving the drug-use problem of treating the cough and dyspnea. The technical scheme is that the traditional Chinese medicine patch is prepared from the following traditional Chinese medicines by weight: 45g-55g of pink reineckea herb, 45g-55g of clematis chinensis, 45g-55g of jamestownweed seeds, 28g-32g of euphorbia kansui, 45g-55g of raw southern star, 45g-55g of tuber pinellia, 45g-55g of herba ephedrae, 28g-32g of Chinese wild ginger, 45g-55g of kadsura peltigera, 28g-32g of brassica alba boiss, 28g-32g of cordyceps sinensis and 28g-32g of borneols. According to the traditional Chinese medicine patch disclosed by the invention, the materials are abundant, the use is convenient and the curative effect is good, and so the traditional Chinese medicine patch is an innovation on the medicine for treating the cough and dyspnea.

The invention relates to an application of total flavonoids of leek seeds in preparing medicines for treating perimenopausal depression, in order to effectively solve the problem on medication for treating the perimenopausal depression. According the application, a method comprises the following steps: crushing the leek seeds into coarse powder, conducting reflux extraction on the coarse powder with the addition of petroleum ether, conducting degreasing and discarding the petroleum ether; volatilizing dregs of the leek seeds until the petroleum ether is removed, soaking the dregs in ethanol, conducting reflux extraction, decompressing an extracting solution and recovering the ethanol till no alcohol taste, and conducting dispersion with the addition of distilled water, so that a sample solution is obtained; processing the sample solution by virtue of AB-8 type macroporous adsorption resin, sequentially eluting the processed sample solution by virtue of distilled water, ethanol which is 10% in mass concentration and ethanol which is 80% in mass concentration, collecting an eluent of 80% ethanol, conducting decompressing and recovering the ethanol till no alcohol taste, implementing extraction with equal volume of petroleum ether and discarding the petroleum ether; and conducting volatilization to remove an organic solvent, freeze-drying a water course and conducting crushing, so that the total flavonoids of the leek seeds are obtained. The total flavonoids of the leek seeds can be used for effectively preparing the medicines for treating the perimenopausal depression; therefore, the application of the total flavonoids of the leek seeds in preparing the medicines for treating the perimenopausal depression is achieved.