Oral ulcer healing membrane with traditional Chinese medicine bioadhesive one-way medicine release

A bioadhesive, one-way technology, applied in the field of medicine, can solve problems such as unsatisfactory use

Inactive Publication Date: 2010-09-08
HENAN UNIV OF CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Therefore, though existing multiple treatment oral ulcer film (oral u

Method used

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  • Oral ulcer healing membrane with traditional Chinese medicine bioadhesive one-way medicine release

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Experimental program
Comparison scheme
Effect test

Embodiment 1

[0011] When the present invention is implemented, it can be realized by the following scheme: 10g of Coptis chinensis, 10g of cortex moutan, 8g of Qingdai, 1g of borneol, 2g of carbomer 934P, 2g of hydroxypropyl cellulose, 2.3g of cyclamate, 10ml of glycerin and ethyl Made from cellulose and dehydrated ethanol, adding 10 times the weight of Indigo Naturalis to 80% ethanol for reflux twice, each time for 0.5h, filtering, merging the filtrates, reclaiming ethanol and concentrating to a relative density of The concentrated solution of 1.05 is for use;

[0012] The mass concentration of 10 times the weight of Rhizoma Rhizoma Rhizoma Rhizome each time is 65% ethanol and refluxed three times, each time for 1 hour, filtered, and the filtrate was combined for subsequent use;

[0013] Moutan cortex is steam distilled to extract paeonol, collect the distilled aqueous solution, add water 8 times the weight of the moutan cortex to the dregs, decoct for 30 minutes to obtain a decoction, co...

Embodiment 2

[0016] When the present invention is implemented, it is also realized by the following scheme: by Huhuanglian 11g, Cortex Moutan 11g, Qingdai 9g, Borneolum 1.5g, Carbomer 934P 3g, hydroxypropyl cellulose 3g, cyclamate 2.4g, glycerin 12ml and It is made of ethyl cellulose and absolute ethanol, wherein, adding 10 times the weight of Indigo Naturalis to 85% ethanol for reflux twice, each time for 0.7h, filtering, combining the filtrates, recovering the ethanol and concentrating to relative Concentrate with a density of 1.05, for later use;

[0017] The mass concentration of 10 times the weight of Rhizoma Rhizoma Rhizoma Rhizome each time is 70% ethanol and refluxed three times, each time for 1.5h, filtered, combined filtrate, and set aside;

[0018] Extract paeonol by steam distillation from Moutan Cortex, collect the distilled aqueous solution, add water 8 times the weight of Moutan Cortex to the dregs, decoct for 40 minutes to obtain a decoction, combine with the distilled aque...

Embodiment 3

[0021] The present invention is made of Coptis chinensis 12g, cortex moutan 12g, Qingdai 10g, borneol 2g, carbomer 934P 4g, hydroxypropyl cellulose 4g, cyclamate 2.5g, glycerin 14ml, ethyl cellulose, and dehydrated alcohol, wherein Adding 10 times the weight of Indigo Daisy to 90% ethanol with a mass concentration of 10 times the weight of Indigo Naturalis refluxed twice, each time for 1 hour, filtering, merging the filtrates, recovering the ethanol and concentrating it to a concentrated solution with a relative density of 1.05 for subsequent use;

[0022] Add Huhuanglian each time with 10 times the weight of Huhuanglian, the mass concentration is 80% ethanol, reflux three times, each time for 2 hours, filter, combine the filtrate, and set aside;

[0023] Extract paeonol from Moutan Cortex with steam distillation, collect the distilled aqueous solution, add 8 times the weight of Moutan Cortex water to the dregs, decoct for 45 minutes to obtain a decoction, combine with the dist...

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Abstract

The invention relates to an oral ulcer healing membrane with traditional Chinese medicine bioadhesive one-way medicine release, capable of effectively solving the problem of used medicines for treating the oral ulcer. The technical scheme for solving the problem is as follows: the ulcer healing membrane is prepared by the following materials: 10-13g of figwortflower picrorhiza rhizome, 10-13g of tree peony bark, 8-11g of natural indigo, 1.5-2.5g of borneol, 2-4g of Carbomer 934P, 2-4g of hydroxy propyl cellulose, 2.3-2.5g of sodium cyclamate, 10-14ml of glycerin and ethyecellulose and absolute ethyl alcohol. The invention has reasonable compatibility of components, advanced and unique method, convenient use and good treatment effect and is innovation for treating oral ulcer.

Description

1. Technical field [0001] The invention relates to the field of medicine, in particular to a traditional Chinese medicine bioadhesive and one-way drug release oral ulcer healing film. 2. Background technology [0002] Recurrent oral ulcer is common disease, frequently-occurring disease, belongs to one of difficult miscellaneous diseases of department of stomatology, and prevalence rate is as high as 25%. Modern medicine believes that its etiology is related to low immune function, bacterial and viral infections, endocrine disorders, autonomic nervous function and digestive tract dysfunction. Traditional Chinese medicine believes that the disease is related to excess heat in the spleen and stomach, inflammation of the heart fire, internal heat due to yin deficiency, internal dampness and heat, mixed with yin deficiency and dampness, which causes burns to the blood and corrodes the sarcolemma, or is caused by deficiency of spleen and kidney yang, deficiency of spleen and stoma...

Claims

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Application Information

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IPC IPC(8): A61K36/80A61K9/70A61K47/38A61P1/02A61K31/045
Inventor 段晓颖高卫芳王小晓
Owner HENAN UNIV OF CHINESE MEDICINE
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