Application of total flavonoids of leek seeds in preparing medicines for treating perimenopausal depression

Abstract

The invention relates to an application of total flavonoids of leek seeds in preparing medicines for treating perimenopausal depression, in order to effectively solve the problem on medication for treating the perimenopausal depression. According the application, a method comprises the following steps: crushing the leek seeds into coarse powder, conducting reflux extraction on the coarse powder with the addition of petroleum ether, conducting degreasing and discarding the petroleum ether; volatilizing dregs of the leek seeds until the petroleum ether is removed, soaking the dregs in ethanol, conducting reflux extraction, decompressing an extracting solution and recovering the ethanol till no alcohol taste, and conducting dispersion with the addition of distilled water, so that a sample solution is obtained; processing the sample solution by virtue of AB-8 type macroporous adsorption resin, sequentially eluting the processed sample solution by virtue of distilled water, ethanol which is 10% in mass concentration and ethanol which is 80% in mass concentration, collecting an eluent of 80% ethanol, conducting decompressing and recovering the ethanol till no alcohol taste, implementing extraction with equal volume of petroleum ether and discarding the petroleum ether; and conducting volatilization to remove an organic solvent, freeze-drying a water course and conducting crushing, so that the total flavonoids of the leek seeds are obtained. The total flavonoids of the leek seeds can be used for effectively preparing the medicines for treating the perimenopausal depression; therefore, the application of the total flavonoids of the leek seeds in preparing the medicines for treating the perimenopausal depression is achieved.

Description

technical field [0001] The invention relates to medicine, in particular to the application of total flavonoids of chive seeds in the preparation of medicines for treating perimenopausal depression. Background technique [0002] Leek seeds first appeared in "Famous Doctors", and are the dry mature seeds of Allium tuberosum Rottler, a plant of the Liliaceae family. Henan is its main production area; proper consumption can regulate the deficiency of liver and kidney in the human body. Leek seeds are used for liver and kidney deficiency, kidney yang deficiency Erectile dysfunction caused by impotence, soreness and pain in the waist and knees. Chives have the functions of nourishing the liver and kidney, warming the waist and knees, and strengthening the kidney and yang. It can be used alone, or together with dodder, psoraleae, epimedium and other kidney-invigorating and yang-invigorating products. It can be used for spermatorrhea, frequent urination, enuresis, and leucorrhea ca...

AI Technical Summary

Problems solved by technology

[0004] Although there are multiple drugs for the treatment of perimenopausal depression, due to various reasons, its use and curative effect are not satisfactory. Therefore, improvement and innovation in the treatment of perimenopausal depression medicine is a problem that those skilled in the art have been studying to solve. So far, there have been no public reports on whether the total flavonoids of leek seeds can be prepared to treat perimenopausal depression

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