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A kind of sunflower disk extract and its medical application in the treatment of constipation

A sunflower disk extract technology, applied in the field of extract preparation, can solve the problems that have not been reported in the literature on the application research of sunflower disk extract, and achieve the effect of increasing the extraction rate

Inactive Publication Date: 2021-12-28
JILIN UNIV +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] At present, there is no literature report on the application of sunflower disc extract in the treatment of constipation

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0015] Weigh 1 portion of powdered sunflower dish and mix it with 10 times the weight of water, soak for 1 hour, heat to 45°C, add 0.25 portion of cellulase to react for 1 hour, then add sodium carbonate to adjust the pH to 9, stir well and then add alkaline Add 0.25 parts of protease and react for 1 hour, then add 0.25 parts of neutral protease and react for 1 hour, then add 0.25 parts of flavor protease and react for 1 hour, filter and concentrate while hot, then spray dry to powder.

Embodiment 2

[0017] Weigh 1 portion of powdered sunflower dish and mix it with 12 times the weight of water, soak it for 1 hour, heat it to 45°C, add 0.5 portion of cellulase to react for 1 hour, then add sodium carbonate to adjust the pH to 9, stir well and then add alkaline Add 0.25 parts of protease and react for 1 hour, then add 0.25 parts of neutral protease and react for 1 hour, then add 0.25 parts of flavor protease and react for 1 hour, then filter and concentrate while hot, and prepare granules with a granulator.

Embodiment 3

[0019] Weigh 1 portion of powdered sunflower dish and mix it with 15 times the weight of water, soak for 1 hour, heat to 45°C, add 0.5 portion of cellulase to react for 1 hour, then add sodium carbonate to adjust the pH to 9, stir well and then add alkaline React 0.5 part of protease for 1 hour, then add 0.25 part of neutral protease and react for 1 hour, then add 0.25 part of flavor protease and react for 1 hour, then filter and concentrate while hot, and prepare granules by granulator.

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PUM

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Abstract

The invention provides a sunflower disc extract and its use in treating constipation. The preparation process of the sunflower disc extract is to soak the powdered sunflower disc in water for a certain period of time, then heat it to 45-55°C, add cellulase to react 1- After 4 hours, add proteolytic enzymes (alkaline protease and neutral protease) to react for 1-2 hours, and finally add flavor protease to react for 1-2 hours, filter and concentrate while hot, and dry into powder or granules. The extraction rate of small molecule peptides and polysaccharides in the sunflower disk extract is greatly increased. The sunflower disk extract can treat constipation, and it has been verified through animal experiments and crowd trials, and the results show that the invention can significantly promote defecation of patients without toxic and side effects.

Description

technical field [0001] The invention discloses a sunflower disc extract and its use in the treatment of constipation, relates to the use of modern technology and technology to prepare the sunflower disc extract for improving constipation, discloses a preparation method of the extract, and belongs to food, health food, The field of pharmaceutical production technology. [0002] technical background [0003] Constipation is a common complex symptom in clinical practice, which mainly refers to decreased frequency of defecation, decreased amount of feces, dry stool, and laborious defecation. Constipation can be mild or severe in degree, and it can be temporary or long-term in time. Constipation, as a chronic gastrointestinal symptom, is extremely common clinically, even surpassing other gastrointestinal symptoms. Clinical data show that constipation is a common symptom of the elderly, and about 1 / 3 of the elderly suffer from constipation. However, with the increasing number of ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/28A61P1/10
CPCA61K36/28A61P1/10A61K2236/331A61K2236/19
Inventor 高波张守琳康明葛振龙杨茂君韩葳葳李婉南韩璐赵海峰常浩周喜鹏
Owner JILIN UNIV
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