36 results about "Glycyrrhiza inflata" patented technology

The invention provides a Radix Glycyrrhizae extract capable of reducing toxicity of drugs to heart. The extract is derived from the root or the rhizome of licorice belonging to the Leguminosae such as Glycyrrhiza uralensis Fisch., Glycyrrhiza inflata Bat. and Glycyrrhiza glabra L.; and mainly contains triterpenoid saponins and flavone glycosides as active ingredients, wherein the content of triterpenoid saponins is 10-30%, and the content of flavone glycosides is 25-80%. The in vivo and in vitro tests show that the Radix Glycyrrhizae extract has distinct protective effect on heart injury induced by adriamycin while not weakening the antitumor effect of anthracycline antitumor drugs; and can be used for preventing and reducing the toxicity of anthracycline drugs to heart, so as to improve the therapeutic effect and clinic application range thereof. The Radix Glycyrrhizae extract can be used for preparing medicines for reducing the toxicity of anthracycline drugs to heart.

The invention discloses new medical application of glycyrrhiza inflata ethanol extract and licochalcone A. The inventor discovers that glycyrrhiza inflata and other medical licorice root have obvious chemical ingredient difference, furthermore systematically researches the glycyrrhiza inflata ethanol extract and the important ingredient licochalcone A therein, and discovers that the glycyrrhiza inflata ethanol extract and the licochalcone A have remarkable activity in protecting oxidized cell injury, tissue injury and acute chemical liver injury. Based on the discovery, the extract and an active compound or pharmaceutically acceptable salt, ester and a solvate, a stereoisomer, tautomer, a prodrug and a mixture thereof can be used for preparing medicaments and health products for treating / preventing oxidative injury and / or acute chemical liver injury.

The invention discloses a rapid molecular identification method for glycyrrhiza uralensis, glycyrrhiza glabra, glycyrrhiza inflate and a hybrid variety thereof. The rapid molecular identification method comprises the following steps: 1) extracting DNA of a sample; 2) amplifying ITS sequences of the sample by using glycyrrhiza ITS specific primers; 3) determining the basic groups at the 159th locus and the 383th to 385th loci from the 5'end of the ITS sequence: if the 159th locus is C, and the 383th to 385th loci are TGC, then identifying the sample to be the glycyrrhiza uralensis; if the 159th locus has the coexistence of C and T, and the 383th to 385th loci have the coexistence TGC and CAA, then identifying the sample to be the hybrid variety; if the 159th locus is T, and the 383th to 385th loci are CAA, then performing a step 4); 4) performing PCR amplification on the ndhC-trnV internal transcribed spacer sequence of the sample; 5) determining the basic group of the 487th locus from the 5' end of the ndhC-trnV internal transcribed spacer sequence: if the 487th locus is A, then identifying the sample to be the glycyrrhiza glabra; if the 487th locus is T, then identifying the sample to be the glycyrrhiza inflate. According to the rapid molecular identification method, original plants, medicinal materials, seeds, seedlings and the like of glycyrrhiza can be identified accurately; the problems about variety identification, breeding cultivation, germplasm resource development and utilization and the like are effectively solved.

The invention relates to a novel use of the Chinese herb Glycyrrhiza inflata in treatment of neurodegenerative disorders. Particularly, the invention relates to the use of ammonium glycyrrhizinate and licochalcone A in targeting polyQ-mediated spinocerebellar ataxia.

The invention discloses gynura procumbens tea capable of relieving cough caused by smoking. The gynura procumbens tea is prepared from the following raw materials in parts by weight: 75-80 parts of gynura procumbens dried leaves, 8-10 parts of honeysuckle flowers, 5-8 parts of fructus momordicae, 5-10 parts of platycodon roots and 1-3 parts of dried roots or dried roots and stems of glycyrrhiza uralensis fisch, glycyrrhiza inflata batalin or glycyrrhiza glabra. The invention further discloses a preparation method of the gynura procumbens tea capable of relieving cough caused by smoking. The preparation method comprises the following steps of firstly, making fresh gynura procumbens leaves into dried gynura procumbens leaves, then uniformly spreading a composite extract of the other raw materials to the dried gynura procumbens leaves, and finally, performing packing. The prepared gynura procumbens tea capable of relieving cough caused by smoking disclosed by the invention is suitable fordiscomfort symptoms of the lung, such as cough, caused by smoking, and the discomfort symptoms of the lung, such as cough, coughing of phlegm, chest distress, asthma and repeated infection, caused bybronchitis and bronchiectasis, damage of smoking crowds to lungs is reduced, and the living and life quality of people is improved.