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Transmission-type fluorescence imaging equipment capable of detecting deep lymphatic vessels and lymph nodes

A technology for lymphatic vessels and lymph nodes, which is applied in the field of transmission fluorescence imaging equipment, can solve the problems of affecting the fluorescence detection effect, adjusting the illumination, and the volume should not be too large, so as to achieve flexible design of the volume and shape of the probe, improve the depth of transillumination, and The effect of the signal-to-noise ratio

Pending Publication Date: 2021-04-09
显微智能科技(湖南)有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, in this solution, since the light source is integrated into the handheld device, due to the limited volume of the handheld device, the volume of the handheld device cannot be too large in the medical inspection work, resulting in a small illuminant of the light source, resulting in insufficient illuminance problems, and the illumination cannot be adjusted according to the needs, which will eventually affect the fluorescence detection effect
At present, only superficial lymphatic vessels and lymph nodes close to the skin can be seen in fluorescein imaging equipment. This is because the usual fluorescein imaging equipment adopts the excitation light reflection fluorescence imaging mode. Since the human body tissue is very thick, the excitation light is difficult. Illuminates from behind and penetrates tissue
Therefore, there is currently no clinically available transmission fluorescein imaging equipment.

Method used

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  • Transmission-type fluorescence imaging equipment capable of detecting deep lymphatic vessels and lymph nodes
  • Transmission-type fluorescence imaging equipment capable of detecting deep lymphatic vessels and lymph nodes
  • Transmission-type fluorescence imaging equipment capable of detecting deep lymphatic vessels and lymph nodes

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Experimental program
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Effect test

Embodiment 1

[0030] Such as Figure 1 ~ Figure 3 As shown, this embodiment provides a transmission fluorescein imaging device capable of detecting deep lymphatic vessels and lymph nodes, including a detection light source 1 and a probe body 2, the detection light source 1 includes a light source body 11, the light source body 11 is a rod-shaped structure, and one end A luminous body 12 is provided, and the other end is connected to a power cord 13 . The probe body 2 is provided with clips 21 , and multiple positions on the light source body 11 can be detachably connected to the clips 21 . One end of the probe body 2 is provided with a camera 22 .

[0031] The light source body 11 is at least partly cylindrical with the same diameter. The clip 21 includes two left-right symmetrical arc-shaped elastic arms, an opening is formed between the two elastic arms, and the light source body is located between the two elastic arms. There is no light source inside the probe.

[0032] The irradiation...

Embodiment 2

[0034] Such as Figure 4 As shown, in this embodiment, the illuminant 12 has a ring structure, 18 bulbs are arranged on the ring, and the inside of the ring is hollow. Other parts in this embodiment are basically the same as those in Embodiment 1.

[0035] Such as Figure 5 , Figure 6 as shown, Figure 5 It is the effect diagram of reflective fluorescence contrast, Figure 6 It is the effect diagram of transmission fluorescence contrast, it can be seen that the effect of transmission fluorescence contrast is better and clearer, and the detection effect is deeper.

[0036] Such as Figure 7 As shown, the top right and bottom of the four pictures in the figure are the scattering state of the laser in human tissue when the diameter of the ring light source is 20mm, 30mm, 40mm, and 50mm, and the detection depths are 4.7mm, 8.2mm, 13.3mm, and 14.8mm respectively. mm. The detection depth of the laser radiation increases with increasing diameter, that is, with increasing fibe...

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Abstract

The invention relates to the field of medical fluorescence detection, in particular to transmission-type fluorescence imaging equipment capable of detecting deep lymphatic vessels and lymph nodes. The transmission-type fluorescence imaging equipment can improve the illuminance of a detection area through a split-type external light source so as to optimize the fluorescence detection effect. The transmission-type fluorescence imaging equipment capable of detecting deep lymphatic vessels and lymph nodes comprises a detection light source and a probe body, wherein the detection light source comprises a light source body, the light source body is of a rod-shaped structure, one end of the light source body is provided with a light-emitting body, and the other end of the light source body is connected with a power line; a clip is arranged on the probe body; a plurality of positions on the light source body can be detachably connected with the clip; and the detection light source is not directly integrated in the probe, so that the probe is more flexible in structural arrangement and convenient to adapt to various requirements.

Description

technical field [0001] The invention relates to the field of medical fluorescence detection, in particular to a transmission fluorescence imaging device capable of detecting deep lymphatic vessels and lymph nodes. Background technique [0002] Fluorescence detection is a natural luminescence reaction, through the reaction of luciferase and ATP, it can detect human cells, bacteria, mold, and food residues. During the working process of the fluorescence detection equipment, the target needs to be irradiated by the fluorescence detection light source, and then the fluorescence reaction is collected by the imaging equipment. [0003] The positions of sentinel lymph nodes and deep lymphatic vessels in the human body are not fixed, and they tend to be buried deep under the skin of the human body. When using fluorescence detection to find relevant parts, it is usually impossible to penetrate human tissues due to insufficient illumination, resulting in fluorescence detection. less ...

Claims

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Application Information

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IPC IPC(8): A61B5/00
CPCA61B5/0071
Inventor 许德冰郭昌盛杨聪
Owner 显微智能科技(湖南)有限公司
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