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A SNP Molecular Marker Affecting Birth Weight of Alpine Merino Sheep and Its Application

A Merino sheep and molecular marker technology, applied in the field of molecular genetics, can solve the problems of slow genetic progress and long breeding cycle, and achieve the effects of high technical accuracy, low cost, and improved breeding accuracy

Active Publication Date: 2022-03-18
LANZHOU INST OF ANIMAL SCI & VETERINARY PHARMA OF CAAS
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Traditional breeding methods mostly use traditional phenotypic breeding techniques, that is, to infer parental productivity based on offspring phenotype information, long breeding cycle, and slow genetic progress

Method used

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  • A SNP Molecular Marker Affecting Birth Weight of Alpine Merino Sheep and Its Application
  • A SNP Molecular Marker Affecting Birth Weight of Alpine Merino Sheep and Its Application
  • A SNP Molecular Marker Affecting Birth Weight of Alpine Merino Sheep and Its Application

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0032] Example 1 Correlation Between Different Genotypes and Birth Weight of Alpine Merino Sheep

[0033] 1. Sample Collection

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Abstract

The invention relates to the technical field of genetic engineering, in particular to a SNP molecular marker affecting the birth weight of Alpine Merino sheep and its application. The SNP molecular marker is located at the 18805219th nucleotide site C>G mutation on chromosome 14 of the International Sheep Reference Genome Oar_v4.0 version. The present invention also relates to a specific primer pair for detecting the above-mentioned SNP molecular marker using SNaPshot technology, a kit containing the specific primer pair and a detection method for nucleotide polymorphism. Compared with the traditional detection method, the technology has the advantages of accuracy High, fast detection speed, low cost, easy to judge the results and so on. SNP locus detection is used to carry out early selection of alpine merino sheep birth weight traits, shorten the breeding cycle and speed up the breeding process, establish an early selection technology for alpine merino sheep birth weight traits, and reduce the alpine merino sheep birth weight traits. The breeding time of excellent traits reduces the breeding cost and has high application value.

Description

technical field [0001] The invention belongs to the technical field of molecular genetics, and in particular relates to a SNP molecular marker affecting the birth weight of Alpine Merino sheep and its application. Background technique [0002] For breeding stock, fecundity is productivity, and reproductive performance is directly related to the economic effect of animal husbandry industry. The reproductive performance of sheep mainly includes indicators such as the total number of lambs born, the number of live lambs born, newborn weight, newborn litter weight, and weaned litter weight. The birth weight of sheep is the birth weight of sheep, which is an important quantitative trait to measure sheep, and affects the growth and development, production performance and carcass grade of sheep. Birth weight was also positively correlated with weaning survival rate, weaning weight and slaughter weight, and negatively correlated with slaughter age. Moreover, sheep with low birth w...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): C12Q1/6888C12N15/11
CPCC12Q1/6888C12Q2600/124C12Q2600/156C12Q2600/172
Inventor 郭婷婷袁超卢曾奎杨博辉岳耀敬牛春娥刘建斌李建烨
Owner LANZHOU INST OF ANIMAL SCI & VETERINARY PHARMA OF CAAS
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