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A blood cell counting and multi-item technology, which is applied in the field of multi-item automatic blood cell counting devices, can solve problems such as difficult to obtain immune dynamic information, and achieve the effect of preventing the decline of immunity and the spread of infection
Active Publication Date: 2021-12-21
曾振武
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In the current clinical field, equipment such as automatic blood cell measurement equipment and flow cytometer are used, but in order to investigate information on Th1 cells, Th2 cells, Th17 cells, regulatory T cells, etc. that are strongly related to immune symptoms, Complica
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no. 1 approach
[0036] like figure 1 As shown, the multi-item automatic blood cell counting device 1 of the first embodiment includes: a basic information generation unit 2 , an immune cell subpopulation detection unit 3 , an immune dynamic change analysis unit 4 , a memory unit 5 and a display unit 6 .
[0037] The basic information generation unit 2 generates analysis results of the number of leukocytes, leukocyte morphology (leukocyte component information), CD numbers of surface antigens of leukocytes (immune cells), and the like.
[0038] In the present embodiment, the basic information generation unit 2 obtains analysis results of the number of leukocytes, leukocyte morphology (leukocyte component information), and CD numbers of surface antigens of leukocytes (immune cells). like figure 1 As shown, the basic information generation unit 2 is composed of a blood cell count detection unit 21 and a surface antigen CD number detection unit 22 .
[0039] In this embodiment, the blood cell...
Embodiment 1
[0061] In the first step, blood is collected from the subject, and the basic information generation unit 2 analyzes the blood to obtain the number of white blood cells, the ratio (%) of basophils in white blood cells, and the ratio (%) of eosinophils. , the proportion of neutrophils (%), the proportion of lymphocytes (%), the proportion of monocytes (%), and information related to CD3 antigen, CD56 antigen (and / or CD16 antigen), CD4 antigen and CD8 antigen The analysis information related to the classification of the CD is stored in the memory unit 5 .
[0062] In the second step, the immune cell subgroup detection unit 3 calculates the total number of white blood cells (immune cells) and the number of white blood cell subgroups (immune cell The total number (number) of each subgroup).
[0063] Specifically, the total number of leukocytes (immune cells) and leukocyte subgroups (immune cell subgroups: granulocytes (eosinophils, basophils, neutrophils), monocytes, lymphocytes (...
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Abstract
The invention provides a multi-purpose automated blood cell counting device which makes it possible to acquire information on an immune dynamics immediately and also makes it possible to identify an immune state accurately. The multi-purpose automated blood cell counting device comprises a basic information production unit, an immune cell subset detection unit, an immune dynamics change analysis unit, a storage unit and a display unit, in which the basic information production unit acquires information on the test of blood cell count and leukocyte differential count of a blood component and information on the analysis of CD classification of a monoclonal antibody capable of binding to a surface antigen of a lymphocyte, the immune cell subset detection unit detects information on an immune cell subset which is necessary for the analysis of the immune state of a subject on the basis of the information on the test of blood cell count and leukocyte differential count of the blood component and the information on the analysis of CD classification of the monoclonal antibody capable of binding to a surface antigen of a lymphocyte, and the immune dynamics change analysis unit identifies information on the change in immune dynamics of the subject on the basis of the information examined in the basic information production unit, the information examined in the immune cell subset detection unit and the data stored in the storage unit, makes an image of the identified information and displays the image on the display unit.
Description
technical field [0001] The invention relates to a multi-item automatic blood cell counting device capable of tracking and checking immune dynamic changes. Background technique [0002] In modern times, clinically, there are many cases of studying the relationship between lymphocytes to study the dynamics of immunity. By studying the dynamics of each immune subgroup, it is possible to infer details about autoimmune diseases, allergic diseases, presence of cancer, progression of cancer status, and cancer. In addition, the study of immune dynamics is not only helpful for the early detection of diseases, but also can be used as an evaluation index for disease prevention and treatment effects and side effects in the treatment of diseases. Early detection and early treatment of diseases in the modern medical field It is gradually becoming an indispensable research project. [0003] As the basic indicators involved in the study of immune dynamics, it is self-evident that the help...
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