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Application of traditional Chinese medicine astragalus membranaceus and radix salviae miltiorrhizae qi-tonifying preparation in treatment of gastrorrhagia

A technology of gastric bleeding and traditional Chinese medicine, applied in pill delivery, blood diseases, drug combination, etc., can solve problems such as lack of effective methods

Pending Publication Date: 2022-01-14
TIANJIN TASLY PHARMA CO LTD
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  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

Clinically, there is a lack of effective methods to prevent and treat gastric bleeding caused by double antibodies

Method used

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  • Application of traditional Chinese medicine astragalus membranaceus and radix salviae miltiorrhizae qi-tonifying preparation in treatment of gastrorrhagia
  • Application of traditional Chinese medicine astragalus membranaceus and radix salviae miltiorrhizae qi-tonifying preparation in treatment of gastrorrhagia
  • Application of traditional Chinese medicine astragalus membranaceus and radix salviae miltiorrhizae qi-tonifying preparation in treatment of gastrorrhagia

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Experimental program
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Effect test

Embodiment 1-9

[0190] 1. Composition: see 13

[0191] Table 13: Composition of Examples 1-9

[0192]

[0193] 2, preparation method, take embodiment 1 as example:

[0194] 1) Weigh 86.5g of Radix Astragali, 21.3g of Salvia Miltiorrhiza, 3.5g of Panax notoginseng, 20.6g of Jiangxiang, and 30g of polyethylene glycol-6000 as an auxiliary material.

[0195] 2) Decoct the pulverized Salvia miltiorrhiza and Panax notoginseng in water for 2 times, add 7 times the amount of water each time for 2 hours each time, combine the decoction liquid, filter, and concentrate the filtrate to 900ml, add 95% ethanol to make the alcohol When the concentration reaches 70%, let stand for 12-24 hours, filter, recover ethanol, and concentrate into an extract with a relative density of 1.32-1.38 (50-60°C);

[0196] 3) Decoct the pulverized Astragalus membranaceus with water twice, add 6 times the amount of water each time, extract for 2 hours and 1 hour in turn, combine the filtrate, and when concentrated to about ...

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Abstract

The invention relates to application of a traditional Chinese medicine astragalus membranaceus and radix salviae miltiorrhizae Qi-tonifying preparation in treatment of gastrorrhagia. The traditional Chinese medicine astragalus membranaceus and radix salviae miltiorrhizae Qi-tonifying preparation is a traditional Chinese medicine composition prepared from four traditional Chinese medicine raw materials including astragalus membranaceus, radix salviae miltiorrhizae, radix notoginseng and lignum dalbergiae odoriferae, wherein the gastrorrhagia is gastromicrovascular hemorrhage and is caused by a double-antibody medicine, the double-antibody medicine is prepared by combining aspirin with another anti-platelet medicine, and the double-antibody medicine is used in a basic therapy for primary and secondary prevention of cardiovascular and cerebrovascular diseases.

Description

technical field [0001] The invention relates to a new application of the traditional Chinese medicine preparation, in particular to the second application of the traditional Chinese medicine Qishen Yiqi preparation, which is to block gastric bleeding caused by aspirin and clopidogrel. [0002] technical background [0003] Cardiovascular and cerebrovascular diseases have a high incidence rate and a high rate of death and disability. They are major diseases that seriously threaten the health of our people. The dual antiplatelet drug consisting of aspirin (ASA) combined with clopidogrel (CLP) is the basic therapy for the primary and secondary prevention of cardiovascular and cerebrovascular diseases recommended by national guidelines. [0004] American College of Cardiology / American Heart Association (ACC / AHA) and European Society of Cardiology guidelines recommend that ASA combined with a P2Y 12 Dual antiplatelet therapy with receptor inhibitors for 12 months or longer. How...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/537A61K9/20A61P1/00A61P7/04
CPCA61K36/481A61K36/537A61K36/258A61K36/48A61K9/2031A61P1/00A61P7/04A61K2236/331A61K2236/39A61K2236/53A61K2300/00
Inventor 韩晶岩战茹玉刘建阎丽潘春水
Owner TIANJIN TASLY PHARMA CO LTD
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