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Traditional Chinese medicine externally applied preparation for treating perianal eczema and preparation method thereof

A traditional Chinese medicine preparation and technology for perianal eczema, applied in the field of traditional Chinese medicine externally used preparations for treating perianal eczema and its preparation, can solve problems such as unsatisfactory effects, speed up blood circulation and lymphatic return, improve curative effect, and the medicine is cheap and easy to obtain Effect

Inactive Publication Date: 2014-04-30
钟山县同古镇卫生院
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Clinically, there is no lack of still using certain traditional Chinese medicines to treat various skin diseases, but the effect is not satisfactory.

Method used

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  • Traditional Chinese medicine externally applied preparation for treating perianal eczema and preparation method thereof
  • Traditional Chinese medicine externally applied preparation for treating perianal eczema and preparation method thereof
  • Traditional Chinese medicine externally applied preparation for treating perianal eczema and preparation method thereof

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Experimental program
Comparison scheme
Effect test

preparation example Construction

[0049] The preparation method of powder of the present invention is: take Burnet 1000g, Senecio 1000g, Sapinberry 1000g, Patrinia 1000g, Purslane 1000g, Rhubarb 1000g, Pinus 1000g, Smilax 1000g, Angelica dahurica 1000g, Atractylodes 1000g, Salvia miltiorrhiza 1000g, Nepeta 1000g, Sophora flavescens 1000g, Baibu 1000g, Phellodendron 1000g, Kochia chinensis 1000g, white moss bark 1000g, Qingdai 1000g; firstly crush the raw material into coarse powder, then further crush it, and pass through a 100-120 mesh sieve , so that the amount of fine powder that can pass through the sieve reaches 30%, collect the fine powder that passes through the sieve to obtain fine powder a; then put the coarse powder that cannot pass through the 120 mesh sieve into a multi-functional extraction tank for extraction twice, and add 10 times for the first time Decoct the amount of water for 1 hour, add 8 times the amount of water for the second time and decoct for 1 hour, combine the two decoctions, and fi...

Embodiment 3

[0076] Embodiment 3: Vaginal mucosa irritation test result

[0077] 1. Test method:

[0078] After 3 days of experimental animal quarantine, 18 above-mentioned healthy rabbits were selected and randomly divided into three groups, each with 6 rabbits, respectively: blank control, vehicle control, and the group of the present invention (5 times the concentration of the application solution). Sterilized tampons of appropriate size soaked in sterilized physiological saline and the test substance were placed in the vagina of the animals in the vehicle control group and the test substance group, and were in contact with the vaginal mucosa for 6 hours, and the animals were sacrificed 24 hours later. The local vaginal tissue was taken out and the lesion was observed.

[0079] 2. Test results: vaginal mucosa irritation test results

[0080]

[0081]

Embodiment 4

[0082] Embodiment 4: skin allergy test result

[0083] Taking the ointment of the present invention as an example, the induction and stimulation contact tests were carried out, and the test mice were observed after 24 hours and 48 hours, and there was no phenomenon such as erythema and edema in the skin, and there was no difference with the negative control group. The results show that the ointment has close to zero skin reaction intensity, that is, no skin allergy.

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PUM

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Abstract

The invention provides an externally applied traditional Chinese medicine preparation for treating perianal eczema. The preparation comprises the following active pharmaceutical ingredients in parts by weight: 10-20 parts of garden burnet root, 10-20 parts of climbing groundsel herb, 10-20 parts of Chinese soapberry fruit, 10-20 parts of dahurian patrinia herb, 10-20 parts of parslane herb, 10-20 parts of rhubarb, 10-20 parts of leaf of shrubby baeckea, 10-20 parts of glabrous greenbrier rhizome, 10-20 parts of dahurian angelica root, 10-20 parts of swordlike atractylodes rhizome, 10-20 parts of radix salviae miltiorrhizae, 10-20 parts of fineleaf schizonepeta herb, 10-20 parts of lightyellow sophora root, 10-20 parts of sessile stemona root, 10-20 parts of amur corktree bark, 10-20 parts of calamine, 10-20 parts of belvedere fruit, 10-20 parts of densefruit pittany root-bark and 10-20 parts of natural indigo. The externally applied traditional Chinese medicine preparation provided by the invention can enable medicines to directly achieve a focus, accelerate the local blood circulation and the lymphatic circulation, shrink skin blood vessels, enable the blood flow to be slow, reduce metabolism, inhibit effusion, effectively relieve pruritus, enable medicine liquid to directly permeate to a skin lesion, accelerate healing of the skin lesion and achieve a good treatment effect; and furthermore, the medicines are low in price, easily-available and worthy of clinical popularization.

Description

technical field [0001] The invention relates to a medical preparation containing components derived from plants, animals or minerals, in particular to a traditional Chinese medicinal preparation for treating perianal eczema and a preparation method thereof. Background technique [0002] Traditional Chinese medicine believes that the etiology of anal eczema is mostly caused by dampness and heat, blood deficiency and wind or food accumulation insects, diet damages the spleen, spleen dysfunction, damp heat accumulation, external invasion by wind evil, filling the interstitial muscles, damp heat and wind evil Struggles, invades the anal skin and sends out. Modern medicine believes that the disease is a skin disease caused by an allergic reaction. It is clinically divided into three types: acute, subacute, and chronic. According to the cause of disease, it is divided into two types: primary and secondary. At present, there is no conclusion on the primary disease, and the seconda...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/904A61P17/00A61K33/30
Inventor 不公告发明人
Owner 钟山县同古镇卫生院
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