Traditional Chinese medicine externally applied preparation for treating perianal eczema and preparation method thereof
A traditional Chinese medicine preparation and technology for perianal eczema, applied in the field of traditional Chinese medicine externally used preparations for treating perianal eczema and its preparation, can solve problems such as unsatisfactory effects, speed up blood circulation and lymphatic return, improve curative effect, and the medicine is cheap and easy to obtain Effect
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[0049] The preparation method of powder of the present invention is: take Burnet 1000g, Senecio 1000g, Sapinberry 1000g, Patrinia 1000g, Purslane 1000g, Rhubarb 1000g, Pinus 1000g, Smilax 1000g, Angelica dahurica 1000g, Atractylodes 1000g, Salvia miltiorrhiza 1000g, Nepeta 1000g, Sophora flavescens 1000g, Baibu 1000g, Phellodendron 1000g, Kochia chinensis 1000g, white moss bark 1000g, Qingdai 1000g; firstly crush the raw material into coarse powder, then further crush it, and pass through a 100-120 mesh sieve , so that the amount of fine powder that can pass through the sieve reaches 30%, collect the fine powder that passes through the sieve to obtain fine powder a; then put the coarse powder that cannot pass through the 120 mesh sieve into a multi-functional extraction tank for extraction twice, and add 10 times for the first time Decoct the amount of water for 1 hour, add 8 times the amount of water for the second time and decoct for 1 hour, combine the two decoctions, and fi...
Embodiment 3
[0076] Embodiment 3: Vaginal mucosa irritation test result
[0077] 1. Test method:
[0078] After 3 days of experimental animal quarantine, 18 above-mentioned healthy rabbits were selected and randomly divided into three groups, each with 6 rabbits, respectively: blank control, vehicle control, and the group of the present invention (5 times the concentration of the application solution). Sterilized tampons of appropriate size soaked in sterilized physiological saline and the test substance were placed in the vagina of the animals in the vehicle control group and the test substance group, and were in contact with the vaginal mucosa for 6 hours, and the animals were sacrificed 24 hours later. The local vaginal tissue was taken out and the lesion was observed.
[0079] 2. Test results: vaginal mucosa irritation test results
[0080]
[0081]
Embodiment 4
[0082] Embodiment 4: skin allergy test result
[0083] Taking the ointment of the present invention as an example, the induction and stimulation contact tests were carried out, and the test mice were observed after 24 hours and 48 hours, and there was no phenomenon such as erythema and edema in the skin, and there was no difference with the negative control group. The results show that the ointment has close to zero skin reaction intensity, that is, no skin allergy.
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