Implants assembled from skeletal polyhedron unit cells, coiled unit cells or mesh unit cells

An implant, polyhedron technology, applied in the field of implants, can solve the problems of having permanent breast implants, unwillingness, etc.

Pending Publication Date: 2022-01-14
TEPHA INC
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] However, more and more patients considering breast reconstruction and breast augmentation are reluctant to have permanent breast implants in their breasts

Method used

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  • Implants assembled from skeletal polyhedron unit cells, coiled unit cells or mesh unit cells
  • Implants assembled from skeletal polyhedron unit cells, coiled unit cells or mesh unit cells
  • Implants assembled from skeletal polyhedron unit cells, coiled unit cells or mesh unit cells

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0211] Example 1: Implants with Porous Lattice of Connected Skeletal Polyhedral Unit Cells Formed by SLS Printing

[0212] prepared as described herein figure 1 Implants shown. P4HB pellets (Tepha, Inc., Mw 480 kDa) were subjected to cryogenic milling followed by continuous sieving to yield a P4HB powder with a particle size of 40 to 60 microns. P4HB powders were made from P4HB pellets with an average size of 2 mm x 2 mm x 3 mm cooled to −70 °C and injected in a cryogenic mill in a high-speed cross-impingement path. The resulting powder was sieved using a 60 micron sieve shaker followed by a 40 micron sieve shaker to intercept particles larger than 60 microns and smaller than 40 microns. The sieved P4HB powder (40 to 60 micron particles) was then dried, flushed with nitrogen, and packed in foil. The moisture content of the P4HB powder is less than 650ppm. P4HB powder was loaded into the powder bed of a 3D selective laser sintering (SLS) printer. Set the thickness of the p...

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Abstract

Absorbable implants can be used to create volume and shape in soft tissues with regenerated tissue. The implants comprise lattices formed from multiple unit cells. Unit cells can be coils or springs, skeletal polyhedrons, foams, or structures derived from mesh and fiber. The implants may be coated or filled with cells and tissues, and preferably with autologous fat graft. The implants are particularly suitable for use in plastic surgery procedures, for example, to regenerate or augment breast tissue following mastectomy or in mastopexy procedures, and can provide an alternative to the use of permanent breast implants in these procedures.

Description

[0001] Cross References to Related Applications [0002] This application claims the benefit of U.S. Provisional Application No. 62 / 855,835, filed May 31, 2019, entitled "IMPLANTS ASSEMBLED FROMSKELETAL POLYHEDRON UNIT CELLS, COILED UNIT CELLS OR MESH UNIT CELLS," the entire contents of which are adopted for all purposes This reference is incorporated herein in its entirety. technical field [0003] The present invention relates generally to implants, and more particularly to absorbable implants formed from three-dimensional unit cells. Background technique [0004] Breast reconstruction after mastectomy has become an integral and important part of breast cancer treatment, and the procedure offers both aesthetic and psychosocial benefits to patients. In the United States, nearly 65 percent of current breast reconstruction operations use tissue expanders to create pockets for permanent breast implants in the first step of the operation. In some patients, pockets for breast ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61F2/12
CPCA61F2210/00A61F2/12A61F2210/0004A61L2430/04A61L27/56A61L27/50A61L27/58A61L27/18A61L27/48C08L67/04A61F2/0063A61L27/3687
Inventor 斯坎德尔·利姆赛义德·里兹克西蒙·F·威廉斯
Owner TEPHA INC
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