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Mailuo Ning oral liquid and its application in pharmacy

A traditional Chinese medicine oral liquid and drug technology, applied in the directions of drug delivery, drug combination, pharmaceutical formulation, etc., can solve problems such as the prevention and treatment of angina pectoris that has not been seen with Mailuoning oral liquid, and solve the problems of therapeutic drugs and preventive drugs, stable quality, and effective Gentle and long-lasting effect

Active Publication Date: 2006-03-22
JINLING PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0002] Currently, Mailuoning Injection is only used by professionals in medical institutions, and there is no report on the prevention and treatment of angina pectoris by Mailuoning Oral Liquid.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0054] Take 425 grams of Achyranthes bidentata, 425 grams of Scrophulariae scrophulariae, 425 grams of dendrobium, and 425 grams of honeysuckle, soak the 4 herbs in 6 times the amount of water for 2 hours, decoct and extract 2 times for 2 hours each time, filter, and combine the filtrates, When concentrated to 80°C, the relative density is 1.15, add ethanol until the alcohol content is 70%, and let stand; take the supernatant, recover ethanol, and concentrate to 80°C, the relative density is 1.35, add ethanol until the alcohol content is 80%, stand still; take the supernatant, recover and remove ethanol, add water to 950ml, refrigerate, filter; add stevioside 1.2g, Tween-80 5.0g, adjust pH to 8.0, filter; add water to the filtrate to 1000ml, Potting, sterilization, that is.

Embodiment 2

[0056] Take 400 grams of Achyranthes bidentata, 400 grams of Scrophulariaceae, 200 grams of Dendrobium, and 500 grams of honeysuckle, soak the 4 medicinal materials in 4 times the amount of water for 0.5 hours, decoct and extract 3 times, each time for 2 hours, filter, and combine the filtrates, When concentrated to 80°C, the relative density is 1.10, add ethanol until the alcohol content is 60%, and let stand; take the supernatant, recover ethanol, and concentrate to 80°C, the relative density is 1.30, add ethanol until the alcohol content is 85%, stand still; take the supernatant, recover and remove ethanol, add water to 960ml, refrigerate, filter; add cyclamate 1.2g, Tween-80 5.0g, adjust pH to 8.5, filter; add water to the filtrate to 1000ml, Potting, sterilization, that is.

Embodiment 3

[0058] Take 600 grams of Achyranthes bidentata, 600 grams of Scrophulariae scrophulariae, 400 grams of dendrobium, and 200 grams of honeysuckle, soak the 4 medicinal materials in 8 times the amount of water for 1 hour, decoct and extract 2 times, each time for 1 hour, filter, and combine the filtrates. When concentrated to 80°C, the relative density is 1.20, add ethanol until the alcohol content is 65%, and let stand; take the supernatant, recover ethanol, and concentrate to 80°C, the relative density is 1.40, add ethanol until the alcohol content is 75%, stand still; take the supernatant, recover and remove ethanol, add water to 940ml, refrigerate, filter; add stevioside 1.2g, Tween-80 5.0g, adjust pH to 8.6, filter; add water to the filtrate to 1000ml, Potting, sterilization, that is.

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PUM

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Abstract

The present invention is Mailuoning oral liquid and its application in pharmaceutical. The Mailuoning oral liquid is prepared with four kinds of Chinese medicinal materials including achyranthes root, figwort, dendrobium stem and honeysuckle, and through water extraction, filtering, concentration; alcohol precipitation to obtain supernatant, recovering alcohol, concentration; alcohol precipitation to obtain supernatant, recovering alcohol, adding water, cold storage, filtering, adding corrective and co-solvent, regulating pH value, filtering, adding water into the filtrate, regulating solution concentration, packing and serilizing. The present invention also discloses the application of Mailuoning oral liquid in preparing medicine for preventing and treating angina pectoris. The medicine for preventing and treating angina pectoris has determined curative effect, lasting and mild effect and stable quality.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicine pharmacy, and in particular relates to a traditional Chinese medicine oral liquid and its application in pharmacy. Background technique [0002] The current clinical use of Mailuoning Injection is limited to the operation and use of professionals in medical institutions, and there is no report on the prevention and treatment of angina pectoris by Mailuoning Oral Liquid. Contents of the invention [0003] The object of the present invention is to provide a kind of oral liquid of traditional Chinese medicine, and this oral liquid of traditional Chinese medicine is also called Mailuoning oral liquid in the present invention. [0004] Another object of the present invention is to provide the application of above-mentioned Mailuoning Oral Liquid in pharmacy. [0005] The object of the present invention can be achieved through the following measures: [0006] A Mailuoning oral liquid, whi...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/8984A61K9/08A61P9/10
Inventor 王兴旺徐向阳杨俊田丽娟张晓静万辉王伟孙晔陈钟陈希张蕙张庆晓张杰张春来范廷校夏云倪洁谢俊蔡莹
Owner JINLING PHARMA
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