3results about How to "Resolve Healing Effects" patented technology

The application discloses a nano material for targeting and driving resuscitation of dying cells, and a preparation method and application thereof. The nano material is a nano platelet vesicle with phosphatidylserine exposed to the outer layer of the membrane after nanoization and centrifugal treatment. The material is obtained by separating and enriching platelets from peripheral blood, then nanoizing the platelets, and then inducing the phosphatidylserine on the platelet membrane to evert through high-speed centrifugation. The material is used for preparing a medicine for promoting tissue repair, and the medicine promotes resuscitation of dying cells by targeting the dying cells and enhancing the membrane repair capacity of the dying cells, so as to promote tissue repair, including repair of orthopedic, muscle, skin, spinal cord or visceral tissue, especially repair of diabetic foot, skin avulsion injury, ischemic skin flap or spinal cord injury. The resuscitation of dying cells is promoted successfully without intervention of lysis programmed cell death initiation, so that the problems of off-target effect and treatment paradox existing in current mainstream small molecule inhibitor strategy are effectively solved.

This invention belongs to the field of physical therapy technology for Parkinson's disease, and provides a non-invasive closed-loop feedback vagus nerve electrical stimulation system for the prevention and treatment of Parkinson's disease. The system includes: a high-frequency electrical stimulator hardware subsystem, transcutaneous nerve stimulation electrodes, a respiratory and heart rate signal acquisition and closed-loop feedback subsystem, and a high-frequency electrical stimulator software subsystem. This invention uses kilohertz stimulation pulses to bidirectionally modulate the vagus nerve, activating afferent C fibers and initiating the anti-inflammatory neural pathway of locus coeruleus noradrenergic neurons, thus alleviating central inflammation. Simultaneously, it blocks A and B efferent fibers, inhibiting mediated α-synuclein retrograde axonal transport. Through multimodal physiological signal monitoring and embedded intelligent algorithms, it achieves real-time, closed-loop, and personalized control of stimulation parameters and automatic switching of stimulation modes, optimizing efficacy and improving safety. Through adhesive electrodes and acquisition devices, it achieves completely non-invasive, wearable, and home-based treatment.

The application discloses a traditional Chinese medicine composition for clearing heat and resolving toxins, benefiting the throat and eliminating swelling, and a preparation method and application thereof, and belongs to the technical field of traditional Chinese medicines. The traditional Chinese medicine composition is prepared from the following raw materials in parts by weight: Houttuynia cordata 10-20 parts, Astragalus root 8-15 parts, Andrographis 8-15 parts, Figwort 8-15 parts, Platycodon 8-15 parts, Monotropa 8-15 parts, Honeysuckle 2-6 parts, Bupleurum 2-6 parts, Belamcanda 2-6 parts, Peucedanum 2-6 parts, Marsh Marigold 1-4 parts and artificial ox gall 0.1-0.6 parts. The traditional Chinese medicine composition has the effects of clearing heat and resolving toxins, benefiting the throat and eliminating swelling, relieving cough and reducing sputum, and is used for treating fever caused by wind-heat invading the lung and lung heat being in excess, nasal discharge of sticky or yellow phlegm, sore throat, cough and expectoration, yellow and thick sputum, headache and body pain, red tongue and yellow tongue fur and the like, and is also used for treating influenza, acute upper respiratory tract infection, acute pharyngitis, tonsillitis and the like. The effect is better than that of each proportion.