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5results about How to "Resolve Healing Effects" patented technology

Appliance combination for expanding root canal filling based on apical biological sealing and application thereof

ActiveCN116763467BResolve Healing EffectsSolve the efficacyTeeth fillingTeeth cappingSilicic acidPhosphoric acid
The application discloses an expanding root canal filling medical device combination based on a dental root tip biological seal and application. The medical device combination comprises a sealant combination and a titanium material root canal plug tip, the sealant combination is composed of liquid agent, A component powder and B component powder which are mutually isolated before use, the A component powder comprises 75-95% of tricalcium silicate and 5-25% of beta tricalcium phosphate, the B component powder comprises 45-55% of nano zirconium dioxide, 44.7-52% of calcium hydroxide and 0.3-3% of calcium oxide; a root canal section surface of the root canal plug tip is provided with a horizontal screw thread, a screw thread groove of the screw thread is used for filling the prepared sealant, and a crown section surface is provided with a retaining groove section. The medical device combination solves the problems of root canal treatment failure or poor long-term curative effect caused by volume shrinkage after filling of the existing sealant and gutta-percha tip, and can realize high safety, high biocompatibility, high quality and high density root canal filling.
Owner:吴瑛

A multitask eeg automatic detection and prediction system for epilepsy

ActiveCN116304575BResolve Healing Effectsproblem solvingForecastingSensorsFeature extractionMedicine
This design is a multi-task automatic EEG detection and prediction system for epilepsy. The system first receives the EEG signals from epilepsy patients to be identified or the collected patient EEG signals used for training the module through a preprocessing module. The preprocessing module performs noise reduction, filtering, segmentation, and normalization on the signals, and outputs the processed patient EEG signals to the training module. In the training module, the collected patient EEG signals are used for training and testing. First, feature extraction is performed using a multi-scale convolutional network. Then, the detection and prediction branches incorporating a dual attention mechanism are trained, and the trained model parameters are saved for use in the detection and prediction module. Finally, the detection and prediction module provides detection and prediction results for the EEG signals from epilepsy patients to be identified. This invention employs a modular design, achieving real-time detection and prediction of noisy, unbalanced EEG signals, providing a reliable system for practical applications.
Owner:HARBIN UNIV OF SCI & TECH

Nanomaterials targeting driving resuscitation of dying cells and preparation method and application thereof

PendingCN122251440Aeffective targetingimprove defectsMuscular disorderAntinoxious agentsTissue repairSpinal cord lesion
The application discloses a nano material for targeting and driving resuscitation of dying cells, and a preparation method and application thereof. The nano material is a nano platelet vesicle with phosphatidylserine exposed to the outer layer of the membrane after nanoization and centrifugal treatment. The material is obtained by separating and enriching platelets from peripheral blood, then nanoizing the platelets, and then inducing the phosphatidylserine on the platelet membrane to evert through high-speed centrifugation. The material is used for preparing a medicine for promoting tissue repair, and the medicine promotes resuscitation of dying cells by targeting the dying cells and enhancing the membrane repair capacity of the dying cells, so as to promote tissue repair, including repair of orthopedic, muscle, skin, spinal cord or visceral tissue, especially repair of diabetic foot, skin avulsion injury, ischemic skin flap or spinal cord injury. The resuscitation of dying cells is promoted successfully without intervention of lysis programmed cell death initiation, so that the problems of off-target effect and treatment paradox existing in current mainstream small molecule inhibitor strategy are effectively solved.
Owner:THE AFFILIATED SIR RUN RUN SHAW HOSPITAL OF SCHOOL OF MEDICINE ZHEJIANG UNIV

A non-invasive closed-loop feedback vagus nerve electrical stimulation system for the prevention and treatment of Parkinson's disease

PendingCN122075925AAddressing neurodegenerative pathological processesSolve the efficacyRespiratory organ evaluationSensorsNoradrenergic neuronsElectrical stimulations
This invention belongs to the field of physical therapy technology for Parkinson's disease, and provides a non-invasive closed-loop feedback vagus nerve electrical stimulation system for the prevention and treatment of Parkinson's disease. The system includes: a high-frequency electrical stimulator hardware subsystem, transcutaneous nerve stimulation electrodes, a respiratory and heart rate signal acquisition and closed-loop feedback subsystem, and a high-frequency electrical stimulator software subsystem. This invention uses kilohertz stimulation pulses to bidirectionally modulate the vagus nerve, activating afferent C fibers and initiating the anti-inflammatory neural pathway of locus coeruleus noradrenergic neurons, thus alleviating central inflammation. Simultaneously, it blocks A and B efferent fibers, inhibiting mediated α-synuclein retrograde axonal transport. Through multimodal physiological signal monitoring and embedded intelligent algorithms, it achieves real-time, closed-loop, and personalized control of stimulation parameters and automatic switching of stimulation modes, optimizing efficacy and improving safety. Through adhesive electrodes and acquisition devices, it achieves completely non-invasive, wearable, and home-based treatment.
Owner:SHANGHAI YANGZHI REHABILITATION HOSPITAL

A traditional Chinese medicine composition for clearing heat and resolving toxins, benefiting the throat and reducing swelling, and a preparation method and use thereof

ActiveCN119280321Bshort treatment cyclelow recurrence rateAntipyreticAnalgesicsAcute PharyngitisBelamcanda chinensis
The application discloses a traditional Chinese medicine composition for clearing heat and resolving toxins, benefiting the throat and eliminating swelling, and a preparation method and application thereof, and belongs to the technical field of traditional Chinese medicines. The traditional Chinese medicine composition is prepared from the following raw materials in parts by weight: Houttuynia cordata 10-20 parts, Astragalus root 8-15 parts, Andrographis 8-15 parts, Figwort 8-15 parts, Platycodon 8-15 parts, Monotropa 8-15 parts, Honeysuckle 2-6 parts, Bupleurum 2-6 parts, Belamcanda 2-6 parts, Peucedanum 2-6 parts, Marsh Marigold 1-4 parts and artificial ox gall 0.1-0.6 parts. The traditional Chinese medicine composition has the effects of clearing heat and resolving toxins, benefiting the throat and eliminating swelling, relieving cough and reducing sputum, and is used for treating fever caused by wind-heat invading the lung and lung heat being in excess, nasal discharge of sticky or yellow phlegm, sore throat, cough and expectoration, yellow and thick sputum, headache and body pain, red tongue and yellow tongue fur and the like, and is also used for treating influenza, acute upper respiratory tract infection, acute pharyngitis, tonsillitis and the like. The effect is better than that of each proportion.
Owner:GUANGZHOU BOJI NEW DRUG CLINICAL RESEARCH CENTER CO LTD