Applications of different elution parts of phlegm-reducing and dysphagia-treating powder, dryness-moistening soup, adenophora stricta and radix ophiopogonis soup as well as qi-tonifying and spleen-strengthening soup in medicines for treating esophagus cancers

Abstract

The invention relates to applications of the different elution parts of phlegm-reducing and dysphagia-treating powder, a dryness-moistening soup, an adenophora stricta and radix ophiopogonis soup as well as a qi-tonifying and spleen-strengthening soup in medicines for treating esophagus cancers, and can be used for effectively solving the problem that whether the parts of the phlegm-reducing and dysphagia-treating powder, the dryness-moistening soup, the adenophora stricta and radix ophiopogonis soup as well as the qi-tonifying and spleen-strengthening soup can be used for treating the esophagus cancers are determined and the treatment effects are improved. A method comprises the following steps: performing gradient elution on the phlegm-reducing and dysphagia-treating powder, the dryness-moistening soup, the adenophora stricta and radix ophiopogonis soup as well as the qi-tonifying and spleen-strengthening soup so as to prepare the ethanol elution parts with different concentrations to act on esophageal cancer cells; screening the effective acting parts capable of inhibiting the proliferation of the esophageal cancer cells from the different elution components of the phlegm-reducing and dysphagia-treating powder, the dryness-moistening soup, the adenophora stricta and radix ophiopogonis soup as well as the qi-tonifying and spleen-strengthening soup so as to obtain the influences of the effective acting parts on the growth of the esophageal cancer cells, thereby realizing the applications mentioned in the invention. The raw materials are abundant and the preparation method is simple. The different elution parts of the phlegm-reducing and dysphagia-treating powder, the dryness-moistening soup, the adenophora stricta and radix ophiopogonis soup as well as the qi-tonifying and spleen-strengthening soup are used for treating the esophagus cancers and have the high treatment effects, thereby being innovative traditional Chinese medicines.

Description

Technical field [0001] The invention relates to medicine, in particular the application of different elution parts of Qige Powder, Tongyou Decoction, Radix Adenophora and Ophiopogon japonicus Decoction, and Buqi Yunpi Decoction in treating esophageal cancer. Background technique [0002] Esophageal cancer is a common malignant tumor of the digestive system. There are 450,000 new cases worldwide every year, and the five-year survival rate is less than 10%. It ranks eighth in the incidence and mortality of malignant tumors worldwide. Ranked sixth. my country is one of the areas with a high incidence of esophageal cancer, especially Linzhou in Henan and Cixian in Hebei. The incidence of esophageal cancer ranks fifth among all types of malignant tumors in the country, and the mortality rate ranks fourth. The ratio of male to female incidence is 1.3~2.7:1, the age of onset is mostly over 40 years old. Surgical treatment can remove the affected parts of esophageal cancer, but 70%...

AI Technical Summary

Problems solved by technology

At present, the treatment of esophageal cancer is mainly comprehensive treatment, but the overall prognosis is still poor, so finding new treatment methods and drugs is the difficulty of current research on the treatment of esophageal cancer

Esophageal cancer belongs to the category of "choking hiccups" in traditional Chinese medicine. It is clinically divided into four types: phlegm-qi obstruction, fluid deficiency heat knot, blood stasis internal knot, and qi deficiency and yang micro-type. The corresponding prescriptions are Qige San, Tongyou Decoction, Shashen Maidong Decoction and Bu Qi Yunpi Decoction, and the Sifang has achieved positive curative effect in clinical application. Experimental studies have also found that the Sifang can inhibit the growth of tumor cells, but the specific action site and mechanism of the Sifang are still not fully understood.

Moreover, Qige San, Tongyou Decoction, Shashen Maidong Decoction and Buqi Yunpi Decoction are not effective in treating esophageal cancer, so how to further study and improve Qige San, Shashen Maidong Decoction, Tongyou Decoction The effect of Hebuqi Yunpi Decoction on the treatment of esophageal cancer is a technical problem to be solved that people care about

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