Applications of different elution parts of phlegm-reducing and dysphagia-treating powder, dryness-moistening soup, adenophora stricta and radix ophiopogonis soup as well as qi-tonifying and spleen-strengthening soup in medicines for treating esophagus cancers

The technology of Shashen Maidong Decoction and Buqi Yunpi Decoction, which is applied in the field of medicine, can solve the problems of incomplete clarity of the action site and action mechanism, poor prognosis, unsatisfactory effect of esophageal cancer, etc., and achieves simple preparation method and abundant raw materials. , improve the effect of curative effect

Inactive Publication Date: 2014-02-05
HENAN UNIV OF CHINESE MEDICINE
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  • Claims
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Problems solved by technology

At present, the treatment of esophageal cancer is mainly comprehensive treatment, but the overall prognosis is still poor, so finding new treatment methods and drugs is the difficulty of current research on the treatment of esophageal cancer
Esophageal cancer belongs to the category of "choking hiccups" in traditional Chinese medicine. It is clinically divided into four types: phlegm-qi obstruction, fluid deficiency heat knot, blood stasis internal knot, and qi deficiency and yang micro-type. The corresponding prescriptions are Qige San, Tongyou Decoction, Shashen Maidong Decoction and Bu Qi Yunpi Decoction, and the Sifang has achieved positive curative effect in clinical application. Experimental studies have also found that the Sifang can inhibit the growth of tumor cells, but the specific action site and mechanism of the Sifang are still not fully understood.
Moreover, Qige San, Tongyou Decoction, Shashen Maidong Decoction and Buqi Yunpi Decoction are not effective in treating esophageal cancer, so how to further study and improve Qige San, Shashen Maidong Decoction, Tongyou Decoction The effect of Hebuqi Yunpi Decoction on the treatment of esophageal cancer is a technical problem to be solved that people care about

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  • Applications of different elution parts of phlegm-reducing and dysphagia-treating powder, dryness-moistening soup, adenophora stricta and radix ophiopogonis soup as well as qi-tonifying and spleen-strengthening soup in medicines for treating esophagus cancers
  • Applications of different elution parts of phlegm-reducing and dysphagia-treating powder, dryness-moistening soup, adenophora stricta and radix ophiopogonis soup as well as qi-tonifying and spleen-strengthening soup in medicines for treating esophagus cancers
  • Applications of different elution parts of phlegm-reducing and dysphagia-treating powder, dryness-moistening soup, adenophora stricta and radix ophiopogonis soup as well as qi-tonifying and spleen-strengthening soup in medicines for treating esophagus cancers

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Embodiment Construction

[0030] The specific implementation of the present invention will be described in detail below in combination with specific situations.

[0031] The present invention is given by the following technical schemes in concrete implementation.

[0032] First of all, the raw materials of Qigesan, Shashen Maidong Decoction, Tongyou Decoction and Buqi Yunpi Decoction were selected respectively. Qigesan was composed of 90g of Adenophora, 90g of Salvia, 30g of Poria, 45g of Chuan Fritillaria, and 15g of Curcuma. , Amomum shell 12g; Tongyou soup is composed of 40g of peach kernel paste, 40g of angelica body, 40g of Cimicifuga, 20g of rehmannia glutinosa, 20g of rehmannia glutinosa, 20g of betel nut, 4g of safflower, and 4g of roasted licorice; Radix Ginseng 90g, Ophiopogon japonicus 90g, Polygonatum 60g, Trichosanthes 45g, Raw lentils 45g, Raw licorice 30g; Buqi Yunpi Decoction consists of 90g Atractylodes macrocephala, 60g ginseng, 45g orange red, 45g Poria, 45g Astragalus, 30g pinellia,...

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Abstract

The invention relates to applications of the different elution parts of phlegm-reducing and dysphagia-treating powder, a dryness-moistening soup, an adenophora stricta and radix ophiopogonis soup as well as a qi-tonifying and spleen-strengthening soup in medicines for treating esophagus cancers, and can be used for effectively solving the problem that whether the parts of the phlegm-reducing and dysphagia-treating powder, the dryness-moistening soup, the adenophora stricta and radix ophiopogonis soup as well as the qi-tonifying and spleen-strengthening soup can be used for treating the esophagus cancers are determined and the treatment effects are improved. A method comprises the following steps: performing gradient elution on the phlegm-reducing and dysphagia-treating powder, the dryness-moistening soup, the adenophora stricta and radix ophiopogonis soup as well as the qi-tonifying and spleen-strengthening soup so as to prepare the ethanol elution parts with different concentrations to act on esophageal cancer cells; screening the effective acting parts capable of inhibiting the proliferation of the esophageal cancer cells from the different elution components of the phlegm-reducing and dysphagia-treating powder, the dryness-moistening soup, the adenophora stricta and radix ophiopogonis soup as well as the qi-tonifying and spleen-strengthening soup so as to obtain the influences of the effective acting parts on the growth of the esophageal cancer cells, thereby realizing the applications mentioned in the invention. The raw materials are abundant and the preparation method is simple. The different elution parts of the phlegm-reducing and dysphagia-treating powder, the dryness-moistening soup, the adenophora stricta and radix ophiopogonis soup as well as the qi-tonifying and spleen-strengthening soup are used for treating the esophagus cancers and have the high treatment effects, thereby being innovative traditional Chinese medicines.

Description

technical field [0001] The invention relates to medicine, in particular to the application of different elution parts of Qige San, Tongyou Decoction, Shashen Maidong Decoction and Buqi Yunpi Decoction in the treatment of esophageal cancer. Background technique [0002] Esophageal cancer (esophageal carcinoma) is a common malignant tumor of the digestive system. There are 450,000 new cases every year in the world, and the five-year survival rate is less than 10%. The incidence rate ranks eighth among malignant tumors worldwide, and the mortality rate Ranked sixth. my country is one of the areas with a high incidence of esophageal cancer, especially Linzhou in Henan and Ci County in Hebei. The incidence of esophageal cancer ranks fifth among all kinds of malignant tumors in the country, and the death rate ranks fourth. The ratio of male to female incidence is 1.3~2.7:1, the age of onset is more than 40 years old. Surgical treatment can remove the diseased part of esophageal c...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9066A61K36/889A61K36/8969A61K36/9064A61P1/00A61P35/00
Inventor 司富春
Owner HENAN UNIV OF CHINESE MEDICINE
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