Technology for producing Dekuiluan lozenge

A technology of dequinium chloride and production process, applied in the field of production technology of dequinium chloride buccal preparations, can solve the problems of short containing time, easily broken containing containing, uneven content of main drug, etc. Long, tablet hardness and uniformity effect

Inactive Publication Date: 2003-08-27
TONGJI MINGZHI MEDICINE WUHAN
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

So as to solve the preparation defects that cannot be solved by conventional technology
Insufficienc...

Method used

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  • Technology for producing Dekuiluan lozenge
  • Technology for producing Dekuiluan lozenge

Examples

Experimental program
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Embodiment Construction

[0014] The following describes the implementation of the present invention in detail with reference to the drawings:

[0015] The invention is implemented under normal pressure, and does not need catalysts and has no special requirements on temperature.

[0016] The key steps of the production process of the dequinonium chloride buccal tablet preparation of the present invention are: dispersing, refining, and granulating.

[0017] Multiplying: Dilute and mix the main drug and auxiliary materials in an equal volume. After solid-solid mixing, solid-liquid mixing, liquid-liquid mixing to liquid-solid mixing, the main drug of this product is evenly diluted to 1:240 (weight ratio ) To ensure that the uniformity of the main drug of this product meets the national legal standards (the 2000 edition of the People’s Republic of China Pharmacopoeia).

[0018] Mixing: Add the doublings to the refined granulated sugar at a ratio of 1:25 (weight ratio) and place it in a temperature-adjusting do...

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Abstract

The production process of dequalinium chloride lozenge successively includes: preparing material, mixing, granulating, drying, mixing, tabletting, metal inspection, foil wrapping and packaging. Said invented production process can be extensively used for producing various lozenge preparations using western medicine as main medicine for curing and preventing the disease of stomatitis, laryngopharyngitis and tonsillitis, etc.

Description

Technical field [0001] The invention relates to a production process of a pharmaceutical preparation, more specifically, it is a production process of a dequalium chloride lozenge preparation. Background technique [0002] At present, most of the buccal tablets produced by domestic pharmaceutical factories are mainly Chinese patent medicines, and are prepared through conventional tableting technology (weighing-mixing-granulating-granulating-tableting-packaging). Such lozenges have curative effects Unclear, bitter taste, poor taste, difficulty swallowing, and the patient’s teeth have stained after medication; there are also a small number of lozenges with western medicine as the main medicine, through the conventional tableting process (weighing-mixing-granulating-granulating- Compression-packaging). Although this type of lozenge has a relatively clear curative effect, it still has shortcomings such as short time for incorporation, easy breakage during incorpo...

Claims

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Application Information

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IPC IPC(8): A61K9/20A61K31/47A61K31/4706A61P1/02A61P11/04
Inventor 常学军
Owner TONGJI MINGZHI MEDICINE WUHAN
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