Colonic irrigation composition

a technology of composition and irrigation water, applied in the field ofcolonic irrigation composition, can solve the problem of frequent spasm of colonic water

Active Publication Date: 2021-10-19
NEW YORK UNIV
View PDF4 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Benefits of technology

[0004]This disclosure provides a composition for use as an irrigation solution during colonoscopy procedure. The composition is termed herein as colonoscopy irrigation composition or colonoscopy irrigation solution. The composition is an aqueous composition and can comprise one or more of a surfactant, a muscle relax

Problems solved by technology

Further, colonic spasm often occurs as a conseque

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Colonic irrigation composition

Examples

Experimental program
Comparison scheme
Effect test

example 1

[0042]In an example, a composition comprising the dye methylene blue and simethicone was used for irrigation in a colonoscopy procedure. The composition comprised 30 mg simethicone and 0.5 ml of a 1% solution of methylene blue in one liter of normal saline or water. In one example, the composition was made up of 30 mg simethicone and 0.5 ml of a 1% solution of methylene blue, and 0.5 ml peppermint oil. Use of this composition provided clear visualization of the mucosal surface of the colon and enhanced visualization of anything that deforms the surface topography of the colonic mucosa, such as, for example, a polyp (FIG. 1B). For comparison, an image of the same colon is without the present irrigation solution is shown in FIG. 1A.

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

PropertyMeasurementUnit
Fractionaaaaaaaaaa
Massaaaaaaaaaa
Massaaaaaaaaaa
Login to view more

Abstract

Provided herein are clear aqueous colonoscopy irrigation compositions, and methods for visualization of colonic mucosa during colonoscopy procedure. The composition comprises indigo, blue or green colored contrast dye, polydimethylsiloxane, and muscle relaxant.

Description

CROSS REFERENCE TO RELATED APPLICATIONS[0001]This application claims priority to U.S. Provisional application No. 62 / 406,651, filed on Oct. 11, 2016, the disclosure of which is incorporated herein by reference.BACKGROUND OF THE DISCLOSURE[0002]Currently, colonoscopy is considered to be the most comprehensive method of colorectal cancer screening—allowing for the detection of potentially pre-cancerous adenomatous polyps. Colonoscopy has been shown to both prevent colorectal cancer and detect cancer early, as evidenced by dramatically declining incidence and mortality rates in recent years. As effective as colonoscopy is, a small percentage of polyps are missed. Further, colonic spasm often occurs as a consequence of colonic manipulation with the colonoscope.[0003]Several compositions are known for preparing the gastrointestinal tract (GI tract) for colonoscopy. These compositions are taken orally by individuals over a period of 24 hours prior to the procedure and help to cleanse the ...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
IPC IPC(8): A61K31/695A61K36/534A61K9/08A61B1/31C08L83/04C09B7/02C09B21/00A61B1/015
CPCA61K31/695A61B1/015A61B1/31A61K9/08A61K36/534C08L83/04C09B7/02C09B21/00A61B2217/007A61K49/006C09B67/0083C08G77/04A61K2300/00C08K3/36C08K5/0041
Inventor POCHAPIN, MARK
Owner NEW YORK UNIV
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap