64 results about "Screening colonoscopy" patented technology

Devices for improving adenoma detection during a colonoscopy and, more particularly, to devices positionable at a distal end of an endoscope and structured or configured to expand and retract upon longitudinal or rotational displacement of at least a portion of the device about the endoscope.

The invention is a device that improves safety and efficiency of colonoscopy by preventing loop formation. It is the plastic overtube with the longitudinal split. The split allows the placement over the shaft of the endoscope when colonoscopy is already in progress and a loop is formed that hinders the further endoscope insertion. The overtube is segmented by oval openings of the split to facilitate placement and to allow using optimal lengths of the overtube. The fastening mechanism is used to close and secure the overtube on the shaft of the endoscope and then it is pushed inside the colon by sliding over the endoscope. Once in place, the overtube is kept steady and provides the semi-rigid conduit for further endoscope insertion. This conduit permits the axial force exerted by the operator to be translated to forward movement of the endoscope tip and eliminates dangerous loop formation.

The invention discloses a marker for early colorectal neoplastic lesion diagnosis and application, and belongs to the technical field of biological medicine. Aiming at the problems of low colonoscopy coincidence rate of colorectal cancer patients at present and limited sensitivity and specificity of existing biomarker diagnosis, LncRNA sequencing research is combined with expanded sample verification to obtain high-specificity and high-sensitivity LncRNA which is highly related to colorectal neoplastic lesions (including adenoma and colorectal cancer), the LncRNA is specifically LOC401585, and the LncRNA has the advantages of high specificity, high sensitivity, high specificity and high sensitivity and can be used for detecting colorectal neoplastic lesions (including adenoma and colorectal cancer). The diagnosis efficacy AUC of the LOC401585 on the adenoma and the colorectal cancer is 0.952 and 0.876 respectively. Therefore, the blood LOC401585 marker can be used for auxiliary diagnosis of colorectal neoplastic lesions, and provides data support for finding novel small molecule drugs with potential treatment value.

The invention provides an effective mucous membrane coverage rate-based colonoscope retreating quality real-time evaluation method and system, and relates to the technical field of medical image calculation and processing. The colonoscope retreating quality real-time evaluation method based on the effective mucous membrane coverage rate comprises the steps that a retreating video is obtained, and the retreating video comprises a real-time retreating video and a historical video; preprocessing the mirror retreating video to obtain an optimized data set; extracting effective frames based on the optimized data set; and inputting the effective frame into a preset image segmentation model to obtain an effective colonic mucosa coverage rate which is used for evaluating the despeculation quality. According to the colonoscope retreating quality real-time evaluation method based on the effective mucous membrane coverage rate, the technical problem that the clinical colonoscope retreating process lacks real-time supervision and feedback in the prior art is solved.

Disclosed herein are methods for administering a dose of a microbiota recovery therapy composition by colonoscopy. The methods disclosed herein are useful for the treatment of diseases and / or conditions of the digestive tract, such as Clostridium difficile infection (GDI), including recurrent GDI, and other gastrointestinal disorders. The method can result in improved quality of life. These methods are capable of altering the gut microbiota composition and / or the gut metabolome composition. The microbiota recovery therapy composition comprises a fecal microbiota suspension comprising: a fecal microorganism derived from a human fecal sample, and a solution of polyethylene glycol and brine.

The utility model relates to the technical field of colonoscopes, in particular to an electronic colonoscopy air bag injection device which comprises an air pump body, an air inlet pipe and an air outlet pipe are installed at the output end of the air pump body, the colonoscopy body is arranged on one side of the air pump body, and the air inlet pipe and the air outlet pipe are connected with the colonoscopy body. Limiting rings are fixedly connected to the ends of the air connecting pipe and the air outlet pipe. According to the electronic colonoscopy air bag injection device, through the arrangement of the air pump body, the air inlet pipe, the air outlet pipe, the colonoscopy body, the limiting ring, the air outlet and the air inlet, when the electronic colonoscopy air bag injection device is used, an external power source of the air pump body conveys air into the air inlet pipe, and the air in the air inlet pipe conveys the air into the limiting ring fixed to the colonoscopy body and is exhausted from the air outlet; when the air is conveyed, the air bag is expanded to swell and expand the intestinal tract, so that the effect of expanding the intestinal tract and preventing the intestinal tract from being damaged due to friction of the colonoscope body is achieved.

To provide peptides and compositions useful for treatment of gastrointestinal disorders or for colon cleansing.SOLUTION: The present invention provides compositions and methods of treating gastrointestinal disorders as well as pharmaceutical compositions for accomplishing the same. In some embodiments, these pharmaceutical compositions include oral dosage forms. The present invention features peptides, compositions and related methods for colon cleansing treatment as well as other conditions and disorders described herein. In one embodiment, the peptides may be used to prepare subjects for colonoscopy treatment. In some embodiments, the peptides or pharmaceutically acceptable salts may be used to prepare subjects for surgery, such as bowel surgery.SELECTED DRAWING: None

Single viewpoint panoramic imaging attachments for a colonoscope are disclosed that are compact in size and provide 360-degree side and rear-views in a single image. One panoramic attachment assembly includes a plurality of micro-imaging subsystems that are positioned around a central opening. Each micro-imaging subsystem includes a reflector to receive light that is reflected from a surrounding tissue, an imaging lens, and a detector to generate signals corresponding to one section of a panoramic image of the surrounding tissue. The micro-imaging subsystems are arranged to all have a common view point, and are configured to collectively form a full 360-degree image of the surrounding tissue.

The present invention relates to a colon cleansing composition with improved ease of administration. The composition minimizes side effects caused by excessive ingredient content in conventional colonic laxatives while providing equivalent or superior intestinal cleansing efficacy, thereby remarkably improving patient compliance and ingestion convenience. In addition, as an uncoated tablet requiring no separate coating processes, a preparation that maintains the quality of tablets such as rapid disintegration and does not have a bitter taste can be provided. The present invention provides a pharmaceutical formulation comprising the colon cleansing composition with improved ease of administration and a method for colon cleansing using the formulation, thereby realizing a patient-centered colon cleansing process and ultimately greatly contributing to the improvement of colonoscopy quality.

A magnetic handpiece for an endoscopic guide is for application in colonoscopy. A magnetic handpiece system includes the magnetic handpiece and a casing. The magnetic handpiece includes a magnetic field source having one or more permanent magnets, and a hollow body having a longitudinal axis, a first end and a second end. A movable support element of the magnetic source is movably accommodated in the hollow body through a screw coupling. The movable support element is movable along the axis between a raised, or non-operating, position and lowered operating positions.

Disclosed are a system and method for analyzing a stool image, which derive the state of the large intestine of a user by analyzing a stool image by using a pre-trained deep learning model. The system for analyzing a stool image may include an input unit configured to receive stool images of a user, a data set generation unit configured to generate a data set by grouping the stool images in chronological order, an analysis unit configured to derive information on a stool state of the user or information on a state of the large intestine of the user by analyzing the data set, and an output unit configured to output the information on the stool state or the information on the state of the large intestine. The endoscopic activity of ulcerative colitis can be predicted from a camera image of stool even without performing a colonoscopy.

The present invention relates to improved methods for screening, diagnosing and / or monitoring colorectal advanced neoplasia (AN), advanced adenoma (AA) and / or colorectal cancer (CRC), wherein AN includes CRC and AA. In particular, the method provides increased specificity due to a reduction in false positive results in fecal occult blood tests (FOBTs) using characteristics based on bacterial markers. The present invention further relates to the use of the method in selecting subjects for exploratory testing (e.g., colonoscopy) or for treatment with anticancer therapy.

This application relates to the field of medical data processing technology, and discloses a screening and intervention system and method for bowel preparation before outpatient colonoscopy, including: providing patients with standardized bowel preparation guidance information; receiving image data of excrement uploaded by patients after bowel preparation; inputting the image data into a pre-trained intelligent judgment model for bowel preparation quality to generate quantitative scores and pass / fail judgment results; and executing an intervention decision process based on the judgment results, including confirming the examination or triggering a rescheduling and supplemental bowel preparation medication instructions. Through the above technical solution, this application achieves objective and quantitative assessment of bowel preparation quality and closed-loop dynamic intervention before examination, effectively improving assessment accuracy, avoiding waste of medical resources, and systematically improving the overall efficiency and safety of outpatient colonoscopy.

Disclosed are various embodiments of systems and methods of deep learning for colorectal polyp screening and providing a prediction of neoplasticity of a polyp. A video of a colonoscopy procedure can be captured. Frames from the video or images associated with the colonoscopy procedure can be extracted. A model for classifying objects that appear in the frames or the images can be obtained. A classification can be determined for a polyp that appears in at least one of the frames or images based on applying the frames or images to an input layer of the model.

Compositions of coated salts are disclosed. Also disclosed herein are methods of coating the inorganic salt(s), masking the taste of the salts and controlling the release of the salts in the gastro-intestinal tract. The granular salts can be coated as is. The powdered salts can be granulated first or spheronized or formed into minitablets or capsules prior to coating. The granulated coated salts are used in colonoscopy preparations and non-colonoscopy preparations.

A sealing device for use in endoscopy includes an elastic body with a leading end, a trailing end, and an inner surface defining a through opening. The outer surface has a smallest diameter in a middle portion and increases toward both ends, forming an hourglass contour that helps anchor within a patient's tissue. The inner surface also has a smallest diameter in its middle portion and broadens toward the ends, permitting a reliable seal around an endoscopic instrument. A slit extends from the leading end toward the middle portion, through the thickness of the body, to allow selective radial deformation during insertion and use. By conforming to various anatomical sizes and maintaining insufflation, this sealing device improves procedural efficiency and patient comfort during colonoscopy or other endoscopic examinations.

1. The name of the design product: colonoscopy simulation training box. 2. The use of the design product: for colonoscopy and treatment simulation training. 3. The design features of the design product: in shape. 4. The picture or photo that best indicates the design features: open state perspective view 1.

Colorectal cancer (CRC) is one of the leading causes of cancer-related mortality in men and women. Uncontrolled proliferation of CRC cells is pivotal in colorectal tumorigenesis and cyclooxygenase-2 (COX-2) is an important regulatory enzyme in this process. Timely diagnosis is the key to life-saving management of CRC, which is under-diagnosed because colorectal aberrant crypt foci, hyper plastic polyps, micro edemas are often missed with conventional colonoscopy. Disclosed herein are imaging agents tagged to nanobodies specific for COX-2 protein that can selectively accumulate and retain in COX-2 expressing cells and colorectal adenomas, resulting in specific and sensitive of early detection, while reducing background and off-target systemic toxicity. The prospect of combining structural and functional imaging readouts obtained with fluorescence-aided colonoscopy measurements would provide powerful diagnostic information for improved management of colorectal carcinogenesis.

Proposed is a colonoscopy area indication method that includes loading a colonoscopy image analysis model and setting an analysis condition of the analysis model by a model loading / condition setting part, and initializing an analysis screen and displaying a picture of a normal colon by a controller, and preprocessing, by an image preprocessing part, a colonoscopy image received through an image receiving part so that subsequent image analysis is smoothly performed, and analyzing the preprocessed colonoscopy image by an image analysis part by using the image analysis model based on AI, and detecting and indicating, on the basis of a result of analysis by the image analysis part, at least one selected from a group of an examination area, a diverticulum area, and a lesion area in the colonoscopy image, and providing, by the controller, the result of analysis performed by the image analysis part.

This invention belongs to the technical field of medical auxiliary equipment, and in particular, relates to a method and apparatus for detecting colon polyps based on endoscopic images. The method comprises the following steps: S1, multi-scale feature extraction based on dilated convolution and a ResNet50 residual network; S2, feature enhancement using frame-assisted contrast learning; S3, prediction based on a CenterNet network; and S4, self-guided bounding box matching during the testing phase. By deploying this efficient detection method on a colonoscopy detection device, the present invention enables real-time and accurate localization of colonoscopic polyps during colonoscopy procedures, improving the efficiency of colonoscopic polyp examination and treatment, reducing the risks associated with multiple examinations and delayed treatment for patients, and providing a strong guarantee for the early diagnosis and treatment of intestinal diseases.

The present disclosure relates to a system and method for generating endoscopic report guidance. The method can be applied to a computing system, or platform, having one or more component servers or computers. The computing system includes receiving patient data of a patient who has gone through a colonoscopy procedure. The computing device further receives endoscopic report data of the patient for the colonoscopy procedure. The endoscopic report data includes indication information including symptoms or reasons for the procedure, and findings and interventions information including details about abnormalities discovered and actions taken during the procedure. The computing device additionally generates, by one or more machine learning models, endoscopic report guidance based on the patient data and the endoscopic report data. The one or more machine learning models may analyze medical diagnostics to provide guidance and recommendations for a medical professional to prepare an endoscopic report.

The invention provides a polyp segmentation method and system for a colonoscopy image, and relates to the technical field of medical image segmentation, and the specific scheme comprises the steps: obtaining a data set for segmentation model training, the data set comprising a marked set and an unmarked set; respectively carrying out supervised training and pseudo-label training on the segmentation model by utilizing a label set and an unlabeled set; performing polyp segmentation on an input colonoscopy image through the trained segmentation model to obtain an image level segmentation result; wherein the pseudo label training comprises the steps of generating an attention graph of an unmarked image by utilizing a segmentation model, adaptively generating a mixed image with a mixed label under the guidance of the attention graph, forming a mixed label set, and training the segmentation model; according to the method, the mixed image with the mixed label is generated for the unmarked image in an intelligent and high-quality manner, the sample diversity is increased, and the polyp segmentation precision is improved.

The invention provides a colonoscope operation nursing scheme determination method and system based on clinical data, and relates to the technical field of colonoscope examination. The method comprises the steps of obtaining clinical data of a patient, obtaining a first feature vector and a second feature vector according to the clinical data, inputting the first feature vector into an improved CNN network, outputting a first nursing scheme, inputting the second feature vector into an improved LSTM network, and outputting a second nursing scheme. According to the method, accurate analysis vectors are constructed by fusing multi-dimensional patient data, a scientific basis of a personalized operation nursing scheme is realized, meanwhile, the effectiveness and pertinence of the scheme are improved by applying double models, a data processing flow is screened and optimized by correlation, and adaptive adjustment is performed on model parameters; and the scientificity, efficiency, patient acceptability and medical service quality of colonoscope operation nursing are comprehensively improved.

Methods for screening subjects who are at an elevated risk of developing cancer due to pathogenic germline variants or hereditary cancer syndrome (HCS). In some aspects, the methods include determining a baseline cancer signal from the subject and performing subsequent diagnostic tests, such as liquid biopsies, at subsequent timepoints to determine the presence or absence of cancer in the subject based on the level and rate of change of the cancer signal. The methods can monitor the level and rate of cancer signal over time and allow are more frequent testing intervals. The methods may also comprise using "gold-standard" screening approaches, such as colonoscopies, in combination with liquid biopsies to detect primary (high risk) cancers and secondary cancers (elevated risk) in the subject. In some embodiments, follow-on assays can be personalized based on the type of pathogenic germline variant(s) / disease suspected or determined to be present in the subject.

Described are colonoscopy systems and methods of using such systems. The colonoscopy systems may include an optical scanning system having at least one illuminator configured to produce spatially patterned light and solid light in at least one frame to illuminate tissue within the colon, and at least one camera configured to capture the at least one image of the illuminated tissue within the colon. Additionally, the optical scanning system may include at least one control system configured to construct at least one three dimensional point cloud representations of the tissue within the colon and detect at least one feature of interest using the at least one three dimensional point cloud and a pre-trained artificial intelligence engine.

The utility model relates to the technical field of colonoscopy nursing, in particular to a nursing device for colonoscopy, which comprises a bottom pad sheet, an arc-shaped groove arranged on the upper surface of the bottom pad sheet close to the left side, a water absorption pad arranged in the arc-shaped groove, a body position layer arranged on the upper surface of the bottom pad sheet close to the corner of the right upper end, and an isolation screen arranged in the middle of the upper surface of the bottom pad sheet. A blind pad towel is arranged at the right end of the isolation screen, a circular groove is formed in the front end face of the isolation screen, and a collecting bag is arranged in the circular groove; according to the nursing device for colonoscopy, the isolation screen with a blind pad towel is arranged to be matched with the bottom pad sheet, the isolation screen is bonded and combined with one side of the bottom pad end through a fixing belt, double layers are used for protection matching of private parts of a patient, a water absorption pad is installed to adsorb liquid dung sprayed out during patient examination, and the pollution influence on the examination environment is reduced; under the cooperation of the collecting bag, the colonoscope penetrates through the round hole and penetrates out of the collecting opening, the collecting opening is aligned with the anus of a patient, sprayed liquid dung can be collected easily, and the influence on environmental pollution is reduced.

The present application relates to a model for training a high-simulation colonoscopy, and relates to the field of a medical training model. The model includes a colon model and a polypus model detachably mounted on the colon model. The colon model is opened and provided with polypus replacing points for mounting the polypus model. The polypus replacing points are provided on different intestinal segments of the colon model. The polypus replacing points are provided at a plurality of different positions in a circumferential direction of the colon model. This application has the effect of simulating a variety of polypus lesion training scenarios, which contributes to the efficient conduct of colonoscopy training.

The invention provides an auxiliary system and method for intestinal preparation before colonoscopy. According to the auxiliary system and method, body fluid loss records of a patient to be examined can be monitored; net liquid loss rates are determined according to the body fluid loss records, and a dynamic balance relation between body fluid and electrolyte of the examined patient is constructed through all the net liquid loss rates; determining efficacy contribution degrees of different metabolites to intestinal preparation, and predicting the intestinal cleanliness of the patient to be examined through a pre-trained cleanliness prediction model; and carrying out fusion evaluation on the dynamic equilibrium relationship between the body fluid and electrolyte of the patient to be examined and the prediction result of the intestinal tract cleanliness to obtain the in-vivo osmotic pressure imbalance risk of the patient to be examined when the intestinal tract is prepared. By adopting the scheme of the invention, non-standardized fluid infusion can be performed on the patient based on the dynamic association relationship between the body fluid loss rate of the patient and the electrolyte concentration change.

The invention relates to the field of medical instruments, in particular to a multifunctional outer sleeve for colonoscopy. Comprising an inner sleeve and a balloon, the balloon is installed on the upper portion of the outer side of the inner sleeve, and the balloon comprises an expansion part; the inner sleeve comprises two cavities, namely a main cavity and an inflation cavity; a one-way valve is arranged at the bottom of the main cavity and used for being inserted into the colonoscope, and one-way sealing is achieved when the colonoscope is pulled out. The inflating cavity is communicated with the balloon through the communicating port and is used for inflating and deflating the balloon; a balloon inflation tube is further arranged and connected with the inflation cavity. The three pain points of pain, gas leakage and out-of-control intestinal pressure in traditional colonoscopy are effectively solved, and the comfort level of a patient, the examination safety and the operation efficiency are remarkably improved.

Devices for improving adenoma detection during colonoscopy, and more particularly, to devices that are positionable at a distal end of an endoscope and are structured or configured to expand and retract upon longitudinal or rotational displacement of at least a portion of the device about the endoscope.