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47 results about "Screening colonoscopy" patented technology

Split Overtube to Prevent Looping During Colonoscopy

The invention is a device that improves safety and efficiency of colonoscopy by preventing loop formation. It is the plastic overtube with the longitudinal split. The split allows the placement over the shaft of the endoscope when colonoscopy is already in progress and a loop is formed that hinders the further endoscope insertion. The overtube is segmented by oval openings of the split to facilitate placement and to allow using optimal lengths of the overtube. The fastening mechanism is used to close and secure the overtube on the shaft of the endoscope and then it is pushed inside the colon by sliding over the endoscope. Once in place, the overtube is kept steady and provides the semi-rigid conduit for further endoscope insertion. This conduit permits the axial force exerted by the operator to be translated to forward movement of the endoscope tip and eliminates dangerous loop formation.
Owner:SADURSKI RAFAL

Marker for early colorectal neoplastic lesion diagnosis and application thereof

The invention discloses a marker for early colorectal neoplastic lesion diagnosis and application, and belongs to the technical field of biological medicine. Aiming at the problems of low colonoscopy coincidence rate of colorectal cancer patients at present and limited sensitivity and specificity of existing biomarker diagnosis, LncRNA sequencing research is combined with expanded sample verification to obtain high-specificity and high-sensitivity LncRNA which is highly related to colorectal neoplastic lesions (including adenoma and colorectal cancer), the LncRNA is specifically LOC401585, and the LncRNA has the advantages of high specificity, high sensitivity, high specificity and high sensitivity and can be used for detecting colorectal neoplastic lesions (including adenoma and colorectal cancer). The diagnosis efficacy AUC of the LOC401585 on the adenoma and the colorectal cancer is 0.952 and 0.876 respectively. Therefore, the blood LOC401585 marker can be used for auxiliary diagnosis of colorectal neoplastic lesions, and provides data support for finding novel small molecule drugs with potential treatment value.
Owner:LONGHUA HOSPITAL SHANGHAI UNIV OF TRADITIONAL CHINESE MEDICINE

Enteroscope retreating quality real-time evaluation method and system based on effective mucous membrane coverage rate

The invention provides an effective mucous membrane coverage rate-based colonoscope retreating quality real-time evaluation method and system, and relates to the technical field of medical image calculation and processing. The colonoscope retreating quality real-time evaluation method based on the effective mucous membrane coverage rate comprises the steps that a retreating video is obtained, and the retreating video comprises a real-time retreating video and a historical video; preprocessing the mirror retreating video to obtain an optimized data set; extracting effective frames based on the optimized data set; and inputting the effective frame into a preset image segmentation model to obtain an effective colonic mucosa coverage rate which is used for evaluating the despeculation quality. According to the colonoscope retreating quality real-time evaluation method based on the effective mucous membrane coverage rate, the technical problem that the clinical colonoscope retreating process lacks real-time supervision and feedback in the prior art is solved.
Owner:WEST CHINA HOSPITAL SICHUAN UNIV

Microbiota recovery therapy (MRT) compositions and methods of administration

PendingCN122055161AAntibacterial agentsBacteriaDiseaseClostridium difficile infections
Disclosed herein are methods for administering a dose of a microbiota recovery therapy composition by colonoscopy. The methods disclosed herein are useful for the treatment of diseases and / or conditions of the digestive tract, such as Clostridium difficile infection (GDI), including recurrent GDI, and other gastrointestinal disorders. The method can result in improved quality of life. These methods are capable of altering the gut microbiota composition and / or the gut metabolome composition. The microbiota recovery therapy composition comprises a fecal microbiota suspension comprising: a fecal microorganism derived from a human fecal sample, and a solution of polyethylene glycol and brine.
Owner:FERRING MICROBIOME LTD

Electronic colonoscopy air bag injection device

The utility model relates to the technical field of colonoscopes, in particular to an electronic colonoscopy air bag injection device which comprises an air pump body, an air inlet pipe and an air outlet pipe are installed at the output end of the air pump body, the colonoscopy body is arranged on one side of the air pump body, and the air inlet pipe and the air outlet pipe are connected with the colonoscopy body. Limiting rings are fixedly connected to the ends of the air connecting pipe and the air outlet pipe. According to the electronic colonoscopy air bag injection device, through the arrangement of the air pump body, the air inlet pipe, the air outlet pipe, the colonoscopy body, the limiting ring, the air outlet and the air inlet, when the electronic colonoscopy air bag injection device is used, an external power source of the air pump body conveys air into the air inlet pipe, and the air in the air inlet pipe conveys the air into the limiting ring fixed to the colonoscopy body and is exhausted from the air outlet; when the air is conveyed, the air bag is expanded to swell and expand the intestinal tract, so that the effect of expanding the intestinal tract and preventing the intestinal tract from being damaged due to friction of the colonoscope body is achieved.
Owner:HUIZHOU CENT PEOPLES HOSPITAL

Compositions for colon cleansing and treatment of gastrointestinal disorders

PendingJP2025169325AOrganic active ingredientsFungiBowel cleansingDisease
To provide peptides and compositions useful for treatment of gastrointestinal disorders or for colon cleansing.SOLUTION: The present invention provides compositions and methods of treating gastrointestinal disorders as well as pharmaceutical compositions for accomplishing the same. In some embodiments, these pharmaceutical compositions include oral dosage forms. The present invention features peptides, compositions and related methods for colon cleansing treatment as well as other conditions and disorders described herein. In one embodiment, the peptides may be used to prepare subjects for colonoscopy treatment. In some embodiments, the peptides or pharmaceutically acceptable salts may be used to prepare subjects for surgery, such as bowel surgery.SELECTED DRAWING: None
Owner:IRONWOOD PHARMACEUTICALS INC

Panoramic view attachment for colonoscopy systems

Single viewpoint panoramic imaging attachments for a colonoscope are disclosed that are compact in size and provide 360-degree side and rear-views in a single image. One panoramic attachment assembly includes a plurality of micro-imaging subsystems that are positioned around a central opening. Each micro-imaging subsystem includes a reflector to receive light that is reflected from a surrounding tissue, an imaging lens, and a detector to generate signals corresponding to one section of a panoramic image of the surrounding tissue. The micro-imaging subsystems are arranged to all have a common view point, and are configured to collectively form a full 360-degree image of the surrounding tissue.
Owner:THE ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIV OF ARIZONA

Colon cleansing composition with enhanced cleansing efficiency and ease of administration

PCT designated stageWO2026005550A1Digestive systemPill deliveryBowel cleansingSide effect
The present invention relates to a colon cleansing composition with improved ease of administration. The composition minimizes side effects caused by excessive ingredient content in conventional colonic laxatives while providing equivalent or superior intestinal cleansing efficacy, thereby remarkably improving patient compliance and ingestion convenience. In addition, as an uncoated tablet requiring no separate coating processes, a preparation that maintains the quality of tablets such as rapid disintegration and does not have a bitter taste can be provided. The present invention provides a pharmaceutical formulation comprising the colon cleansing composition with improved ease of administration and a method for colon cleansing using the formulation, thereby realizing a patient-centered colon cleansing process and ultimately greatly contributing to the improvement of colonoscopy quality.
Owner:MOTHERS PHARMA CO LTD

System and method for stool image analysis

Disclosed are a system and method for analyzing a stool image, which derive the state of the large intestine of a user by analyzing a stool image by using a pre-trained deep learning model. The system for analyzing a stool image may include an input unit configured to receive stool images of a user, a data set generation unit configured to generate a data set by grouping the stool images in chronological order, an analysis unit configured to derive information on a stool state of the user or information on a state of the large intestine of the user by analyzing the data set, and an output unit configured to output the information on the stool state or the information on the state of the large intestine. The endoscopic activity of ulcerative colitis can be predicted from a camera image of stool even without performing a colonoscopy.
Owner:KYUNGPOOK NAT UNIV IND ACADEMIC COOP FOUND

Improved methods for screening, diagnosis and / or monitoring of colorectal advanced neoplasia, advanced adenomas and / or colorectal cancer

The present invention relates to improved methods for screening, diagnosing and / or monitoring colorectal advanced neoplasia (AN), advanced adenoma (AA) and / or colorectal cancer (CRC), wherein AN includes CRC and AA. In particular, the method provides increased specificity due to a reduction in false positive results in fecal occult blood tests (FOBTs) using characteristics based on bacterial markers. The present invention further relates to the use of the method in selecting subjects for exploratory testing (e.g., colonoscopy) or for treatment with anticancer therapy.
Owner:GOODGUT SL +2

Screening and intervention system for outpatient colonoscopy pre-bowel preparation and method thereof

PendingCN122177346AImage analysisDrug and medicationsBowel preparationData treatment
This application relates to the field of medical data processing technology, and discloses a screening and intervention system and method for bowel preparation before outpatient colonoscopy, including: providing patients with standardized bowel preparation guidance information; receiving image data of excrement uploaded by patients after bowel preparation; inputting the image data into a pre-trained intelligent judgment model for bowel preparation quality to generate quantitative scores and pass / fail judgment results; and executing an intervention decision process based on the judgment results, including confirming the examination or triggering a rescheduling and supplemental bowel preparation medication instructions. Through the above technical solution, this application achieves objective and quantitative assessment of bowel preparation quality and closed-loop dynamic intervention before examination, effectively improving assessment accuracy, avoiding waste of medical resources, and systematically improving the overall efficiency and safety of outpatient colonoscopy.
Owner:TIANJIN MEDICAL UNIVERSITY GENERAL HOSPITAL +1

Systems and methods of deep learning for colorectal polyp screening

ActiveUS12499537B2Image enhancementImage analysisAdenocarcinoma polypsRadiology
Disclosed are various embodiments of systems and methods of deep learning for colorectal polyp screening and providing a prediction of neoplasticity of a polyp. A video of a colonoscopy procedure can be captured. Frames from the video or images associated with the colonoscopy procedure can be extracted. A model for classifying objects that appear in the frames or the images can be obtained. A classification can be determined for a polyp that appears in at least one of the frames or images based on applying the frames or images to an input layer of the model.
Owner:UNIV OF SOUTH FLORIDA

Sealing device for use in endoscopy

A sealing device for use in endoscopy includes an elastic body with a leading end, a trailing end, and an inner surface defining a through opening. The outer surface has a smallest diameter in a middle portion and increases toward both ends, forming an hourglass contour that helps anchor within a patient's tissue. The inner surface also has a smallest diameter in its middle portion and broadens toward the ends, permitting a reliable seal around an endoscopic instrument. A slit extends from the leading end toward the middle portion, through the thickness of the body, to allow selective radial deformation during insertion and use. By conforming to various anatomical sizes and maintaining insufflation, this sealing device improves procedural efficiency and patient comfort during colonoscopy or other endoscopic examinations.
Owner:MARECIK SLAWOMIR

Colonoscopy simulation training box

1. The name of the design product: colonoscopy simulation training box. 2. The use of the design product: for colonoscopy and treatment simulation training. 3. The design features of the design product: in shape. 4. The picture or photo that best indicates the design features: open state perspective view 1.
Owner:PEKING UNIVERSITY FIRST HOSPITAL (PEKING UNIVERSITY FIRST CLINICAL MEDICAL COLLEGE)

Colonoscopy area indication system and method

PendingUS20260127742A1Image enhancementImage analysisNormal colonImaging analysis
Proposed is a colonoscopy area indication method that includes loading a colonoscopy image analysis model and setting an analysis condition of the analysis model by a model loading / condition setting part, and initializing an analysis screen and displaying a picture of a normal colon by a controller, and preprocessing, by an image preprocessing part, a colonoscopy image received through an image receiving part so that subsequent image analysis is smoothly performed, and analyzing the preprocessed colonoscopy image by an image analysis part by using the image analysis model based on AI, and detecting and indicating, on the basis of a result of analysis by the image analysis part, at least one selected from a group of an examination area, a diverticulum area, and a lesion area in the colonoscopy image, and providing, by the controller, the result of analysis performed by the image analysis part.
Owner:WAYCEN INC

A method and device for detecting colon polyps based on endoscopic images

This invention belongs to the technical field of medical auxiliary equipment, and in particular, relates to a method and apparatus for detecting colon polyps based on endoscopic images. The method comprises the following steps: S1, multi-scale feature extraction based on dilated convolution and a ResNet50 residual network; S2, feature enhancement using frame-assisted contrast learning; S3, prediction based on a CenterNet network; and S4, self-guided bounding box matching during the testing phase. By deploying this efficient detection method on a colonoscopy detection device, the present invention enables real-time and accurate localization of colonoscopic polyps during colonoscopy procedures, improving the efficiency of colonoscopic polyp examination and treatment, reducing the risks associated with multiple examinations and delayed treatment for patients, and providing a strong guarantee for the early diagnosis and treatment of intestinal diseases.
Owner:CHANGCHUN UNIV OF SCI & TECH

System and method for generating endoscopic report guidance using machine learning models

The present disclosure relates to a system and method for generating endoscopic report guidance. The method can be applied to a computing system, or platform, having one or more component servers or computers. The computing system includes receiving patient data of a patient who has gone through a colonoscopy procedure. The computing device further receives endoscopic report data of the patient for the colonoscopy procedure. The endoscopic report data includes indication information including symptoms or reasons for the procedure, and findings and interventions information including details about abnormalities discovered and actions taken during the procedure. The computing device additionally generates, by one or more machine learning models, endoscopic report guidance based on the patient data and the endoscopic report data. The one or more machine learning models may analyze medical diagnostics to provide guidance and recommendations for a medical professional to prepare an endoscopic report.
Owner:GYRUS ACMI INC

Screening approaches for high cancer risk individuals

Methods for screening subjects who are at an elevated risk of developing cancer due to pathogenic germline variants or hereditary cancer syndrome (HCS). In some aspects, the methods include determining a baseline cancer signal from the subject and performing subsequent diagnostic tests, such as liquid biopsies, at subsequent timepoints to determine the presence or absence of cancer in the subject based on the level and rate of change of the cancer signal. The methods can monitor the level and rate of cancer signal over time and allow are more frequent testing intervals. The methods may also comprise using "gold-standard" screening approaches, such as colonoscopies, in combination with liquid biopsies to detect primary (high risk) cancers and secondary cancers (elevated risk) in the subject. In some embodiments, follow-on assays can be personalized based on the type of pathogenic germline variant(s) / disease suspected or determined to be present in the subject.
Owner:GUARDANT HEALTH INC

Colonoscopy system and method

Described are colonoscopy systems and methods of using such systems. The colonoscopy systems may include an optical scanning system having at least one illuminator configured to produce spatially patterned light and solid light in at least one frame to illuminate tissue within the colon, and at least one camera configured to capture the at least one image of the illuminated tissue within the colon. Additionally, the optical scanning system may include at least one control system configured to construct at least one three dimensional point cloud representations of the tissue within the colon and detect at least one feature of interest using the at least one three dimensional point cloud and a pre-trained artificial intelligence engine.
Owner:OPTECKS LLC

Nursing device for colonoscopy

The utility model relates to the technical field of colonoscopy nursing, in particular to a nursing device for colonoscopy, which comprises a bottom pad sheet, an arc-shaped groove arranged on the upper surface of the bottom pad sheet close to the left side, a water absorption pad arranged in the arc-shaped groove, a body position layer arranged on the upper surface of the bottom pad sheet close to the corner of the right upper end, and an isolation screen arranged in the middle of the upper surface of the bottom pad sheet. A blind pad towel is arranged at the right end of the isolation screen, a circular groove is formed in the front end face of the isolation screen, and a collecting bag is arranged in the circular groove; according to the nursing device for colonoscopy, the isolation screen with a blind pad towel is arranged to be matched with the bottom pad sheet, the isolation screen is bonded and combined with one side of the bottom pad end through a fixing belt, double layers are used for protection matching of private parts of a patient, a water absorption pad is installed to adsorb liquid dung sprayed out during patient examination, and the pollution influence on the examination environment is reduced; under the cooperation of the collecting bag, the colonoscope penetrates through the round hole and penetrates out of the collecting opening, the collecting opening is aligned with the anus of a patient, sprayed liquid dung can be collected easily, and the influence on environmental pollution is reduced.
Owner:ZHUJIANG HOSPITAL OF SOUTHERN MEDICAL UNIVERSITY

Multifunctional outer sleeve for colonoscopy

The invention relates to the field of medical instruments, in particular to a multifunctional outer sleeve for colonoscopy. Comprising an inner sleeve and a balloon, the balloon is installed on the upper portion of the outer side of the inner sleeve, and the balloon comprises an expansion part; the inner sleeve comprises two cavities, namely a main cavity and an inflation cavity; a one-way valve is arranged at the bottom of the main cavity and used for being inserted into the colonoscope, and one-way sealing is achieved when the colonoscope is pulled out. The inflating cavity is communicated with the balloon through the communicating port and is used for inflating and deflating the balloon; a balloon inflation tube is further arranged and connected with the inflation cavity. The three pain points of pain, gas leakage and out-of-control intestinal pressure in traditional colonoscopy are effectively solved, and the comfort level of a patient, the examination safety and the operation efficiency are remarkably improved.
Owner:NANJING HOSPITAL OF TCM

Device for improving adenoma detection

PendingCN122438641AEndoscopeAdenoma
Devices for improving adenoma detection during colonoscopy, and more particularly, to devices that are positionable at a distal end of an endoscope and are structured or configured to expand and retract upon longitudinal or rotational displacement of at least a portion of the device about the endoscope.
Owner:CONMED CORP

Portable edge ai-assisted diagnosis and quality control system for gastrointestinal endoscopy

In a decision-support system for gastrointestinal (GI) endoscopy, convolutional neural networks (CNNs) are set up to perform decision-support tasks according to endoscopic images. Each learnable kernel used in the CNNs is advantageously modeled as a linear combination of a set of fixed kernels for simplifying kernel learning, giving a lightweight kernel model to advantageously reduce required computation resources. Further computation-resource reduction can be made by CNN model compression via knowledge distillation and by using multi-task CNNs. It enables the decision-support system to be realized as an edge computing system near a site of performing endoscopic examinations. The system can be automatically configured for esophagogastroduodenoscopy (EGD) or colonoscopy. In the system, lesion-detection results and quality-control results can be seamlessly integrated to provide value-added results, which are more valuable to the endoscopist than separately considering the lesion-detection results and quality-control results.
Owner:HONG KONG APPLIED SCI & TECH RES INST

Coloscope tail end pose control method, system and device

The invention relates to the technical field of colonoscopy, and provides a colonoscope tail end pose control method, system and device, and the colonoscope tail end pose control method comprises the steps: obtaining a colonoscope initial image and the real-time pose of the colonoscope tail end in real time; inputting the initial image of the colonoscope into a preset colon model to obtain registration parameters of the tail end of the colonoscope; registering the actual pose of the colonoscope tail end with a virtual pose in a preset colon model based on the registration parameters; analyzing the initial image of the colonoscope by adopting a preset image analysis model to obtain correction parameters of the tail end of the colonoscope; and correcting the position and posture of the colonoscope tail end based on the correction parameters to obtain the optimal position and posture of the colonoscope tail end. According to the colonoscope tail end pose control method, the technical problem that position detection of the tail end and effective pose adjustment during colonoscope retreating in the prior art are lacked is solved.
Owner:SICHUAN UNIV

Apparatus, systems, and methods for mapping of tissue oxygenation

ActiveUS12419550B2SurgeryEndoscopesSurgical operationTissue viability
Apparatus, systems, and methods are provided that generate in vivo maps of oxygenation measurements of biological tissue. These may include surgical instruments and stand-alone imaging systems with incorporated oxygen sensing capability. Oxygenation maps can be determined via fluorescent or phosphorescent lifetime imaging of an injectable probe with an oxygen-dependent optical response. Probe configuration and methods and apparatus of injecting the probe into the tissue are provided. Methods and apparatus for temperature compensation of temperature-dependent lifetime measurements are provided to improve oxygenation measurement accuracy. Oxygen maps may be registered with visible light images to assist in assessing tissue viability or localize anomalies in the tissue. Resulting oxygen images may be used for various applications including, but not limited to, guiding surgical procedures such as colorectal resection through use of intraoperative sensing, enhanced endoscopic imaging for identifying suspect lesions during colonoscopy, and external imaging of tissue such as assessing peripheral vascular disease.
Owner:SURGISENSE CORP

Intelligent colon polyp edge sketching method based on medical image

The invention relates to the technical field of edge segmentation, in particular to an intelligent colon polyp edge sketching method based on medical image.The method comprises the steps that in the colonoscopy process, edge detection is conducted on each frame of image in collected colon internal detection image data, and a plurality of nested intestinal wall contour curves are obtained; determining the normal deviation degree of each position point based on the normal direction change of each position point on the intestinal wall profile curve, and further determining a polyp position point on the intestinal wall profile curve; and based on curvature change and normal direction change of adjacent position points of the polyp position points on the intestinal wall contour curve, determining a polyp edge end point of the polyp position points, and performing colon inner wall polyp contour sketching in each frame of image. The polyp edge recognition precision is effectively improved by accurately positioning the polyp protruding area on the intestinal wall and drawing the edge contour.
Owner:THE FIRST AFFILIATED HOSPITAL OF XIAN MEDICAL UNIV

Diabetes patient colonoscopy hypoglycemia risk prediction model and method

PendingCN122177475AMedical simulationHealth-index calculationBowel preparationHypoglycemia
This invention relates to the field of risk prediction technology, specifically to a model and method for predicting the risk of hypoglycemia during colonoscopy in diabetic patients. The model includes a feature extraction module, a weight analysis module, a model construction module, a model calibration module, and a risk prediction module. In this invention, core clinical features such as patient age, bowel preparation score, fasting time, and specific medication usage are extracted. A hypoglycemia risk nomogram prediction model is constructed using weight analysis. The model is then dynamically calibrated by calculating the prediction fitting deviation. These techniques enable precise quantification of the probability of hypoglycemia during colonoscopy in diabetic patients and provide early warning of high-risk conditions. This helps medical personnel identify potential risks in advance, optimize personalized fasting and medication care plans, effectively avoid serious adverse cardiovascular and neurological events, and ultimately ensure that diabetic patients can undergo colonoscopy normally.
Owner:THE FIRST AFFILIATED HOSPITAL OF XIAMEN UNIV

System and method for indicating part of colonoscopic examination

A method for indicating a part of colonoscopic examination according to the present invention comprises the steps in which: a model loading / condition setting unit loads a colonoscopy image analysis model and sets analysis conditions of the analysis model; a control unit initializes an analysis screen and displays a picture of a normal large intestine; an image preprocessing unit preprocesses a colonoscopy image received via an image reception unit so that subsequent image analysis may be smoothly performed; an image analysis unit analyzes the preprocessed colonoscopy image by using an AI-based image analysis model; the image analysis unit detects and indicates at least one of an examination part, a diverticulum part, or a lesion part from the colonoscopy image on the basis of the analyzed result; and the control unit provides the result analyzed by the image analysis unit.
Owner:WAYCEN INC

Endoscopic guide, in particular for colonoscopes, and endoscopy system comprising said guide

An endoscopic guide and an endoscopy system are for colonoscopy. The endoscopy system includes an endoscopic guide for colonoscopes, including a tubular guide element and an anchoring head. The tubular guide element includes a longitudinal cavity. The anchoring head is provided with an expandable container configured to accommodate a ferromagnetic agent, the expandable container being in communication with the longitudinal cavity. The endoscopy system further includes a ferromagnetic agent configured to be movable in the longitudinal cavity to fill / empty the expandable container, and the ferromagnetic agent is an aqueous suspension of carbonyl iron.
Owner:ENDOSTART SRL

Floating drug delivery system for salts in solid form in intestinal cleansing products

PendingCN121358468ADigestive systemPharmaceutical non-active ingredientsBowel cleansingMucosal lesion
The present disclosure provides systems, kits, and methods for preparation prior to colonoscopy or other colon-related gastrointestinal procedures. In particular, the present invention provides a drug delivery system for gut cleansing products and procedures. The drug delivery system includes a capsule or tablet assembly that can be loaded with salts and other related drugs for use in gut cleansing products and still floats in the stomach after ingestion due to a density of 1.004 gm / ml or less. The drug delivery system avoids mass aggregation of salt near the gastric mucosa during the disintegration phase, thereby reducing the risk of direct gastric mucosal damage that may occur by solid enteral cleansing products.
Owner:DARK CANYON LAB LLC