Prebiotic mixture

a technology of prebiotic compositions and polysaccharide fibres, which is applied in the direction of biocide, plant/algae/fungi/lichens, biocide compositions, etc., can solve the problems of sudden gas production with the ensuing relative discomfort, the inability to tolerate the ingestion of polysaccharide fibre-based prebiotic compositions by subjects, and the general indisposition of subjects with a consequent low complian

Inactive Publication Date: 2015-01-29
ABOCA S P A SOC AGRI
View PDF9 Cites 10 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Benefits of technology

[0016]In such pathologies, the capability of the mixture and of the composition of delay or inhibiting the formation of intestinal gases is particularly useful, as those lack painful side effects due to a sudden development of gas in the intestine caused by a component having a strong prebiotic activity (i.e., the fibres).

Problems solved by technology

Various data present in the scientific literature demonstrate how the intake of polysaccharide fibres-based prebiotic compositions is scarcely tolerated by subjects intaking them, owing to the significant production of gas during the intestinal fermentation thereof.
In particular, excessive CO2 production in the intestine entails side effects such as intestinal swelling, also referred to as abdominal swelling, abdominal tension and pain, which cause states of general indisposition with a consequent low compliance by the subject.
In fact, it has been demonstrated that non-tolerability partly depends on fibre structure; e.g., short fibres and / or fibres with bonds that can be easily attacked are fermented more quickly, leading to a sudden production of gas with the entailed relative discomfort.

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Prebiotic mixture
  • Prebiotic mixture
  • Prebiotic mixture

Examples

Experimental program
Comparison scheme
Effect test

examples

1. Prebiotic Activity Demonstration

[0133]The in vitro model utilized to study the prebiotic activity of embodiments of the prebiotic mixtures according to the present invention is the “Batch Culture” model: In particular, it is a reactor simulating the physiological conditions present in the colon. In the model inoculated with the mixtures to be tested, a positive control and a negative control according to the scheme reported below, microbiota evolution over 24 hours subsequent to inoculation is observed. In particular, through FISH technique it is possible to single out the quantitative evolution of given bacterial strains or classes over 24 hours.

[0134]Negative control: faeces only

[0135]Positive control: chicory inulin (HP, high degree of polymerization), average DP (polymerization degree): ≧10 (1%)

[0136]Positive control: chicory inulin GR, average DP: >23 (1%)

[0137]Tests: 1% Inulin GR+0.1% lyophilized extract (individual extracts or in mixture).

[0138]Mixtures (#5) (for all tests...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

PropertyMeasurementUnit
timeaaaaaaaaaa
timeaaaaaaaaaa
timeaaaaaaaaaa
Login to view more

Abstract

The present invention refers to a prebiotic mixture comprising at least one plant polysaccharide fibre and at least one of Propolis and/or Olea europaea and/or Aloe vera extracts, optionally comprising also Thymus vulgaris and/or Agrimonia eupatoria extracts. Moreover, the present invention also relates to said mixture for use in the preservation and/or in the restoration of the intestinal microbiota balance.

Description

[0001]The present invention refers to a prebiotic mixture comprising at least one plant polysaccharide fibre and at least one of Propolis and / or Olea europaea and / or Aloe vera extracts, optionally comprising also a Thymus vulgaris and / or Agrimonia eupatoria extract. Moreover, the present invention also relates to said mixture for use in the preservation and / or restoration of the intestinal microbiota balance.STATE OF THE PRIOR ART[0002]In the literature, a large number of studies demonstrate how intestinal bacterial flora plays a relevant role on the health conditions of a subject, basically a human being (Hawrelak, J. A., & Myers, S. P. (2004). The causes of intestinal dysbiosis: a review. Altern Med Rev, 9(2), 180-197.). Accordingly, several research groups turned their attention to understanding the relations existing among intestinal microbiota balance and predisposition, onset and / or treatment of some pathological conditions, both intestinal and extra-intestinal ones. Commonly,...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
Patent Type & Authority Applications(United States)
IPC IPC(8): A61K36/906A61K36/185A61K36/53A61K36/73A61K36/63A61K36/28A61K36/886A61K31/733A61K35/64A23L29/244A61K35/644
CPCA61K36/906A61K31/733A61K36/185A61K36/53A61K36/73A61K36/63A61K36/28A61K36/886A61K35/644A61K2300/00A23L29/244A23L33/21A61P1/14
Inventor MERCATI, VALENTINOMERCATI, VALENTINALUGLI, ANDREAMAIDECCHI, ANNA
Owner ABOCA S P A SOC AGRI
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products