Preparation method of medical bandage coated with polyurethane resin prepolymer

Abstract

The invention discloses a preparation method of a medical bandage coated with a polyurethane resin prepolymer. The preparation method comprises the following steps: a. adding aromatic diisocyanate and a dehydrating agent to a reaction kettle, stirring, adding polyether glycol, polyether triols, high molecular polyethylene glycol, a defoaming agent, white carbon black, a lubricant and a catalyst, heating up to 75 DEG C and preserving heat, and then cooling to room temperature to obtain a polyurethane prepolymer; b. adding powdery nanoparticles, zinc oxide and a far infrared emitting material to absolute ethyl alcohol and a coupling agent solution, sufficiently stirring, drying and grinding to obtain functional powder; c. adding the functional powder to the polyurethane prepolymer, and sufficiently stirring for reacting under a nitrogen protection condition to obtain the polyurethane resin prepolymer; and d. uniformly coating base cloth with the polyurethane resin prepolymer, and conveying, rolling, coiling, shearing, sealing and bagging to obtain the medical bandage coated with the polyurethane resin prepolymer.

Description

technical field

[0001] The invention relates to the technical field of polymer medical products, in particular to a method for preparing a medical bandage coated with a polyurethane resin prepolymer. Background technique

[0002] Existing polyurethane bandages are mainly used for fixation of fractures, joint dislocation injuries, orthopedic deformities, and can also be used for fixation after surgery for peripheral nerves, blood vessels, and tendons. Due to surgical bone injuries, it generally takes about 4-10 weeks to recover. The current bandages are in contact with the body surface for a long time, and the moisture, bacteria, and fungi emitted from the surface of the human skin will stay at the interface between the bandage and the body surface, breed and multiply, and cause allergic phenomena such as itching, redness, and swelling to infect the wound, causing Qi and blood are not smooth, which is not conducive to the recovery of bone injuries and aggravates the suffering...

Examples

preparation example Construction

[0011] The invention discloses a method for preparing a medical bandage coated with a polyurethane resin prepolymer, comprising the following steps: a. Preparation of the polyurethane prepolymer: adding 50 to 65 parts of aromatic diisocyanate, 0.1 ~1 part of dehydrating agent, after stirring at room temperature for 20 minutes, then add 20~30 parts of polyether diol, 2~5 parts of polyether triol, 5~15 parts of high molecular weight polyethylene glycol Alcohol, 2-4 parts of defoamer, 5-10 parts of white carbon black, 1-5 parts of lubricant, 1-2 parts of catalyst, slowly raise the temperature to 75°C, keep it warm for 1.5 hours, and then lower it to room temperature, The polyurethane prepolymer is obtained; b. Preparation of functional body powder: add powdered nano-scale particles, zinc oxide, and far-infrared emitting materials to absolute ethanol and coupling agent solution, and fully stir at 70°C for 3 to 4 hours , dried at 80°C for 5 hours, and ground to obtain functional bo...

Embodiment 1

[0017] Add 1000g of MDI diisocyanate and 15g of benzoyl chloride into the reaction kettle with thermometer, stirrer and nitrogen inlet and outlet in sequence, stir fully for 20min, add polyoxypropylene ether glycol 750g, its molecular weight is 2000, polyoxypropylene ether Trihydric alcohol 250g, its molecular weight is 300, add polyethylene glycol 100g, its molecular weight is 6000, slowly heat up to 75°C, keep warm for 1.5h, cool down to room temperature, add polyethylene oxide 50g, nano-scale calcium oxide 50g, nano-scale White carbon black 150g, stirred for 1h under nitrogen protection, made polyurethane prepolymer for use; mixed nano-scale silver particles, zinc oxide particles, titanium dioxide particles, and fluorite particles in equal mass proportions, totaling 80g, added with condensing reflux 1. In the reaction kettle with mechanical stirring device, add 100g of absolute ethanol, 20g of silane coupling agent, and 5g of PVP in sequence. Dry at 80°C for 5 hours, grind ...

Embodiment 2

[0019] Put 1000g of TDI diisocyanate and 20g of benzoyl chloride into the reaction kettle with a thermometer, a stirrer and a nitrogen inlet and outlet in sequence, stir thoroughly for 20min, add 600g of polyethylene glycol, its molecular weight is 1000, polyoxypropylene ether ternary Alcohol 300g, its molecular weight is 600, add polyethylene glycol 200g, its molecular weight is 6000, slowly heat up to 75°C, keep warm for 1.5h, cool down to room temperature, add polyethylene oxide 50g, nano-sized molecular sieve 60g, nano-sized white carbon black 100g, stirred for 1h under the protection of nitrogen to make polyurethane prepolymer for use; mix nano-sized copper particles, zinc oxide particles, titanium dioxide particles, and tourmaline particles in the ratio of equal mass 2:1:1:1:1, a total of 70g , put it into the reaction kettle with condensing reflux and mechanical stirring device, add 100g of absolute ethanol, 20g of silane coupling agent, 5g of PVP in sequence, its molecu...

technical field

[0001] The invention relates to the technical field of polymer medical products, in particular to a method for preparing a medical bandage coated with a polyurethane resin prepolymer. Background technique

[0002] Existing polyurethane bandages are mainly used for fixation of fractures, joint dislocation injuries, orthopedic deformities, and can also be used for fixation after surgery for peripheral nerves, blood vessels, and tendons. Due to surgical bone injuries, it generally takes about 4-10 weeks to recover. The current bandages are in contact with the body surface for a long time, and the moisture, bacteria, and fungi emitted from the surface of the human skin will stay at the interface between the bandage and the body surface, breed and multiply, and cause allergic phenomena such as itching, redness, and swelling to infect the wound, causing Qi and blood are not smooth, which is not conducive to the recovery of bone injuries and aggravates the suffering...

Examples

preparation example Construction

[0011] The invention discloses a method for preparing a medical bandage coated with a polyurethane resin prepolymer, comprising the following steps: a. Preparation of the polyurethane prepolymer: adding 50 to 65 parts of aromatic diisocyanate, 0.1 ~1 part of dehydrating agent, after stirring at room temperature for 20 minutes, then add 20~30 parts of polyether diol, 2~5 parts of polyether triol, 5~15 parts of high molecular weight polyethylene glycol Alcohol, 2-4 parts of defoamer, 5-10 parts of white carbon black, 1-5 parts of lubricant, 1-2 parts of catalyst, slowly raise the temperature to 75°C, keep it warm for 1.5 hours, and then lower it to room temperature, The polyurethane prepolymer is obtained; b. Preparation of functional body powder: add powdered nano-scale particles, zinc oxide, and far-infrared emitting materials to absolute ethanol and coupling agent solution, and fully stir at 70°C for 3 to 4 hours , dried at 80°C for 5 hours, and ground to obtain functional bo...

Embodiment 1

[0017] Add 1000g of MDI diisocyanate and 15g of benzoyl chloride into the reaction kettle with thermometer, stirrer and nitrogen inlet and outlet in sequence, stir fully for 20min, add polyoxypropylene ether glycol 750g, its molecular weight is 2000, polyoxypropylene ether Trihydric alcohol 250g, its molecular weight is 300, add polyethylene glycol 100g, its molecular weight is 6000, slowly heat up to 75°C, keep warm for 1.5h, cool down to room temperature, add polyethylene oxide 50g, nano-scale calcium oxide 50g, nano-scale White carbon black 150g, stirred for 1h under nitrogen protection, made polyurethane prepolymer for use; mixed nano-scale silver particles, zinc oxide particles, titanium dioxide particles, and fluorite particles in equal mass proportions, totaling 80g, added with condensing reflux 1. In the reaction kettle with mechanical stirring device, add 100g of absolute ethanol, 20g of silane coupling agent, and 5g of PVP in sequence. Dry at 80°C for 5 hours, grind ...

Embodiment 2

[0019] Put 1000g of TDI diisocyanate and 20g of benzoyl chloride into the reaction kettle with a thermometer, a stirrer and a nitrogen inlet and outlet in sequence, stir thoroughly for 20min, add 600g of polyethylene glycol, its molecular weight is 1000, polyoxypropylene ether ternary Alcohol 300g, its molecular weight is 600, add polyethylene glycol 200g, its molecular weight is 6000, slowly heat up to 75°C, keep warm for 1.5h, cool down to room temperature, add polyethylene oxide 50g, nano-sized molecular sieve 60g, nano-sized white carbon black 100g, stirred for 1h under the protection of nitrogen to make polyurethane prepolymer for use; mix nano-sized copper particles, zinc oxide particles, titanium dioxide particles, and tourmaline particles in the ratio of equal mass 2:1:1:1:1, a total of 70g , put it into the reaction kettle with condensing reflux and mechanical stirring device, add 100g of absolute ethanol, 20g of silane coupling agent, 5g of PVP in sequence, its molecu...