3 results about "Excessive appetite" patented technology

Provided herein are therapeutic methods for treatment using an agonist leptin receptor (LEPR) antibody, an antigen-binding fragment thereof, or a composition comprising the LEPR antibody or an antigen-binding fragment thereof. Such methods of treatment include treating conditions associated with metabolic dysfunction, including, for example, lipodystrophy, obesity predisposition or obesity, weight loss, non-alcoholic fatty liver disease, overappetite, hyperglycemia, insulin resistance, dyslipidemia, hepatic steatosis, and infertility.

Provided herein are therapeutic methods of treatment using an agonist leptin receptor (LEPR) antibody, antigen-binding fragment thereof, or a composition comprising the LEPR antibody or antigen-binding fragment thereof, to perform the treatment. Such therapeutic methods include treating conditions associated with metabolic dysfunction, including, for example, lipodystrophy, obesity predisposition or obesity, weight loss, nonalcoholic fatty liver disease, bulimia, hyperglycemia, insulin resistance, dyslipidemia, hepatic steatosis, and infertility.

This invention discloses a traditional Chinese medicine composition for improving blood sugar, its preparation method, and its application, belonging to the field of traditional Chinese medicine compound technology. The composition is prepared by combining scorpion, centipede, jujube seed, dandelion, cardamom, and platycodon in specific weight proportions. Based on the pathological mechanism of integrated traditional Chinese and Western medicine, this invention establishes liver phlegm obstruction, abnormal liver qi rising, and liver stagnation with internal heat disturbing the hypothalamus as the core pathogenesis of type 2 diabetes. Phlegm and dampness stagnation in the liver collaterals leads to impaired liver glycogen synthesis, and compensatory hyperactivity of the hypothalamus causes elevated blood sugar, polyphagia, and polydipsia. Deficiency of peripheral fluids and blood induces muscle atrophy and prediabetic foot lesions. This invention abandons the drawbacks of traditional yin-nourishing drugs that are greasy and promote dampness, using insect-derived drugs to clear phlegm and dampness from the liver collaterals, combined with herbs that clear the liver, nourish the liver, strengthen the spleen, and promote lung function. It regulates glucose metabolism at multiple targets, calms hypothalamic central hyperactivity, and nourishes the extremities. This formula can be prepared at home. It has a mild medicinal effect, stabilizes blood sugar, improves dry mouth and excessive appetite, numbness and atrophy of limbs, and slows the progression of diabetic foot. It has clinical application and industrial transformation value.