Torasemide freeze-drying preparation and prepration method

A torasemide and freeze-drying technology, which is applied in the direction of freeze-drying delivery, drug combination, blood diseases, etc., can solve the problems of increasing related substances, vascular stimulation, and affecting curative effect
CN100372534CActive Publication Date: 2008-03-05南京海辰药业股份有限公司

Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
南京海辰药业股份有限公司
Publication Date
2008-03-05

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Abstract

A freeze-dried composition of torasemide features that it contains sodium hydrogen carbonate for higher solubility. Its preparing process is also disclosed.
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Description

technical field

[0001] The invention relates to the field of pharmaceutical preparations, in particular to a torasemide freeze-dried preparation and a preparation method. Background technique

[0002] Torsemide, the English name is Torsaemide,

[0003] The chemical structural formula is as follows:

[0004]

[0005] Molecular formula: C 16 h 20 N 4 o 3 S

[0006] Molecular weight: 348.43

[0007] It is white or off-white loose lumps. It is a new generation of sulfonylurea loop diuretics researched and developed by Boehringer Mannheim in Germany. It was first launched in Germany in 1993 and approved by the US FDA in 1994. The drug is sold in many countries and regions such as the United States, Canada, Switzerland, and Hong Kong. This drug is the fourth loop diuretic on the market today. It is mainly used clinically to treat various edemas caused by congestive heart failure, kidney or liver diseases, etc. And various types of hypertension, it is a milestone drug i...

Claims

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