Tripterine capsule in use for preventing and treating disease of nerve damage, preparation method and usage

A technology of tripterine and capsules, which can be applied to nervous system diseases, pharmaceutical formulas, medical preparations containing active ingredients, etc., can solve the problems of Alzheimer's disease treatment that remains to be seen, and achieve the effect of safe use

Inactive Publication Date: 2007-12-26
SHENZHEN PAIPAI TECH +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Trehalose has an effect on the cause of Alzheimer's disease (AD),

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0025] 1. Take an appropriate amount of tripteryglide with a purity greater than 98% from natural sources, crush it, pass it through a 100-mesh sieve, and dry it at 80°C;

[0026] 2. Take an appropriate amount of trehalose from natural sources with a purity greater than 98%, crush it, pass it through a 100-mesh sieve, and dry it at 80°C;

[0027] 3. Weigh 1 kg of tripterine, and then weigh 100 kg of trehalose;

[0028] 4. Mix 1 kg of tripterine and 1 kg of trehalose evenly to obtain a mixture of tripterine: trehalose = 1:1;

[0029] 5. Add 2 kg of trehalose to the above mixture to obtain a mixture of tripterine: trehalose=1:3;

[0030] 6. As in step 5, increase the amount in equal increments until a homogeneous mixture of tripterine: trehalose = 1: 100 kg is obtained;

[0031] 7. Put the homogeneous mixture into empty capsules, each capsule weighs 200 mg, bottle the capsules, 30 capsules per bottle, seal the bottle mouth tightly, affix a label, and pack the capsule;

[0032...

Embodiment 2

[0035] 1. Take an appropriate amount of tripteryglide with a purity greater than 98% from natural sources, crush it, pass it through a 100-mesh sieve, and dry it at 80°C;

[0036] 2. Take an appropriate amount of trehalose from natural sources with a purity greater than 98%, crush it, pass it through a 100-mesh sieve, and dry it at 80°C;

[0037] 3. Weigh 1 kg of tripterine, and then weigh 500 kg of trehalose;

[0038] 4. Mix 1 kg of tripterine and 1 kg of trehalose evenly to obtain a mixture of tripterine: trehalose = 1:1;

[0039] 5. Add 2 kg of trehalose to the above mixture to obtain a mixture of tripterine: trehalose=1:3;

[0040] 6. As in step 5, increase the amount in equal increments until a homogeneous mixture of tripterine: trehalose = 1:500 is obtained;

[0041] 7. Put the homogeneous mixture into empty capsules, each capsule weighs 500 mg, bottle the capsules, 120 capsules per bottle, seal the bottle mouth tightly, affix a label, and pack the capsule;

[0042] 8...

Embodiment 3

[0045] 1. Take an appropriate amount of tripteryglide with a purity greater than 98% from natural sources, crush it, pass it through a 100-mesh sieve, and dry it at 80°C;

[0046] 2. Take an appropriate amount of trehalose from natural sources with a purity greater than 98%, crush it, pass it through a 100-mesh sieve, and dry it at 80°C;

[0047] 3. Weigh 1 kg of tripterine, and then weigh 1000 kg of trehalose;

[0048] 4. Uniformly mix 1 weight unit of tripterine with 1 weight unit of trehalose to obtain a mixture of tripterine: trehalose = 1:1;

[0049] 5. Add another kilogram of trehalose to the above mixture to obtain a mixture of tripterine: trehalose=1:3;

[0050] 6. As in step 5, increase the amount in equal increments until a homogeneous mixture of tripterine: trehalose = 1:1000 is obtained;

[0051] 7. Put the homogeneous mixture into empty capsules, each capsule weighs 800 mg, bottle the capsules, 200 capsules per bottle, seal the bottle mouth tightly, affix a label,...

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PUM

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Abstract

The present invention relates to a tripterine capsule for preventing and curing the diseases due to nerve injury and its preparation method. Said capsule is made up by using natural tripterine whose purity is 98% as main raw material and adding natural mycose whose purity is 98% as auxiliary material through a certain preparation process. Said tripterine capsule can be mainly used for curing the diseases of Alzheimer's disease (AD), Parkinson's disease (PD), Huntington's disease (HD) and other diseases due to nerve injury.

Description

technical field [0001] The patent of the present invention "Prevention and Treatment of Nerve Injury Disease Tripterygium Capsules and Its Preparation and Usage" involves the use of tripterygne with a purity greater than 98% from natural sources as the main raw material, and the compounding of natural sources with a purity greater than 98% Trehalose, made into capsules, is used for nerve damage diseases such as Alzheimer's disease (AD), Parkinson's disease (PD), Huntington's disease (HD), bulbar spinal muscular atrophy (KD), lateral spinal cord Treatment of diseases such as cord sclerosis (ALS) and spinal cord injury. These diseases are caused by the dissimilation and curling of the functional protein structure in the brain nerve cells, which cannot perform normal functions and cause diseases. At present, there is no good treatment method. Trehalose has the effect of hindering the formation of functional protein structure dissimilation in brain nerve cells. Tripteryglide can ...

Claims

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Application Information

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IPC IPC(8): A61K31/7016A61K31/56A61P25/14A61P25/16A61P25/28A61P43/00
Inventor 袁晓周东斌袁萍姜意
Owner SHENZHEN PAIPAI TECH
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