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Pharmaceutical combination with hypnogenesis, depression resistance and angst resistance effect and method of preparing the same

A composition and anti-anxiety technology, which is applied in the direction of drug combination, medical preparations containing active ingredients, pharmaceutical formulas, etc., can solve the problems of slow onset of effect, many adverse reactions of chemical drugs, and low efficiency

Active Publication Date: 2008-09-03
SHENZHEN TONIC MEDICINE TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Because the chemical drugs for the treatment of such diseases generally have disadvantages such as many adverse reactions, obvious side effects, and high prices, patients often refuse to take them.
Traditional Chinese medicine has a certain curative effect on the above-mentioned diseases, but the effective rate of Chinese patent medicines for treating insomnia such as Tianwang Buxin Pills, Anshen Bunao Liquid, Zhusha Anshen Pills, and Tianmeng Capsules currently on the market is not high, and the onset of effect is slow; Chinese patent medicines with no definite effect on antidepressant and anti-anxiety

Method used

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  • Pharmaceutical combination with hypnogenesis, depression resistance and angst resistance effect and method of preparing the same
  • Pharmaceutical combination with hypnogenesis, depression resistance and angst resistance effect and method of preparing the same
  • Pharmaceutical combination with hypnogenesis, depression resistance and angst resistance effect and method of preparing the same

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0161] [Example 1] Preparation of granules of the pharmaceutical composition of the present invention

[0162] Weigh 15g of Chuanxiong, 20g of Pinellia, and 10g of Gardenia, and set aside.

[0163] Extract Chuanxiong, pinellia, and gardenia with 8 times the amount of 70% ethanol for 3 times, each time for 1 hour, filter, combine the filtrate, recover ethanol under reduced pressure, concentrate under reduced pressure below 60°C to form a thick paste, add appropriate amount of powdered sugar, Made into soft material, extruded and granulated, dried below 60°C, granulated, and packaged to obtain the final product; or the thick paste was dried under reduced pressure to a dry paste, crushed into dry paste powder, and dry granulated to obtain the final product.

Embodiment 2

[0164] [embodiment 2] tablet preparation of pharmaceutical composition of the present invention

[0165] Weigh 15g of Chuanxiong, 20g of Pinellia, 5g of Coptidis, 15g of Zhuru, and 12g of Citrus aurantium, and set aside.

[0166] Extract Chuanxiong, Pinellia, and Coptidis with 8 times the amount of 70% ethanol for 3 times, each time for 1 hour, filter, combine the filtrates, recover ethanol under reduced pressure, and dry under reduced pressure below 60°C to obtain component 1;

[0167] Add bamboo rutabaga and citrus aurantii with 10 times the amount of water and decoct 3 times, each time for 1 hour, filter, combine the filtrate, concentrate to a relative density of 1.05-1.15 (heat measurement at 70-85°C), let stand, filter, concentrate the filtrate, Dry to obtain component 2;

[0168] Combine component 1 and component 2, pulverize into powder, mix evenly, and press into tablets to obtain.

Embodiment 3

[0169] [embodiment 3] capsule preparation of pharmaceutical composition of the present invention

[0170] Weigh 15g of Chuanxiong, 20g of Pinellia, 10g of Gardenia or 5g of Coptidis, 12g of Codonopsis, and 9g of Chenpi, and set aside.

[0171] Extract Chuanxiong and pinellia with 8 times the amount of 70% ethanol for 3 times, each time for 1 hour, filter, combine the filtrates, recover ethanol under reduced pressure, dry below 60°C to obtain component 1.

[0172] Add 5g of Gardenia or Coptis chinensis, Codonopsis pilosula, and tangerine peel with 10 times the amount of water and decoct 3 times, each time for 1 hour, filter, combine the filtrate, concentrate to a relative density of 1.05-1.15 (70-85°C thermal measurement), stand still, and filter , the filtrate was concentrated and dried to obtain component 2;

[0173] Combine component 1 and component 2, pulverize into fine powder, pass through a No. 6 sieve, fill in hard capsules, and obtain.

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Abstract

The invention discloses a pharmaceutical composition with the effects of hypnosis, anti-depression and anti-anxiety, and belongs to the traditional Chinese medicine field. The pharmaceutical raw materials of the pharmaceutical composition are: 6 to 40 parts by weight of Szechuan lovage rhizome and 10 to 40 parts by weight of pinellia tuber which are taken as monarch drugs; and 3 to 20 parts by weight of cape jasmine fruit or 1 to 15 parts by weight of golden thread which are taken as ministcrial drugs. The pharmaceutical composition can be prepared into any common preparation form for internal usage. The different adjuvant drugs or guide drugs can be added on the basis of the monarch drugs and the ministcrial drugs according to the different individual differences, so as to play the better efficacy. The pharmaceutical composition of the invention has the effects of hypnosis, anti-depression and anti-anxiety, the efficacy for the treatment of insomnia, depression and anxiety disorder is exact, the onset of action is fast, and the pharmaceutical composition can also be used for the treatment of insomnia, melancholia, headache, palpitation and other diseases of the traditional Chinese medicine.

Description

[technical field] [0001] The invention relates to a pharmaceutical composition with hypnotic, antidepressant and anti-anxiety effects and a preparation method thereof, belonging to the field of traditional Chinese medicines. [Background technique] [0002] With the development of human beings and the progress of society, people's work and lifestyle are constantly changing, social competition is increasing, and physical activity is getting less and less. Therefore, insomnia, depression, and anxiety have become frequent health problems that plague people. . Because the chemical drugs for the treatment of such diseases generally have many adverse reactions, obvious side effects, and high prices, patients often refuse to take them. Traditional Chinese medicine has a certain curative effect on the above-mentioned diseases, but the effective rate of Chinese patent medicines for treating insomnia such as Tianwang Buxin Pills, Anshen Bunao Liquid, Zhusha Anshen Pills, and Tianmeng ...

Claims

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Application Information

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IPC IPC(8): A61K36/8888A61K36/899A61K36/8905A61P25/20A61P25/24A61P25/22
CPCA61K36/8888A61K36/899A61K36/744A61K36/718A61K36/8905A61K36/344A61K36/75A61K36/725A61K36/57A61K36/752A61K36/236A61K36/233A61P25/20A61P25/22A61P25/24
Inventor (发明人请求不公开姓名)
Owner SHENZHEN TONIC MEDICINE TECH
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