Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Application of radix scrophulariae in preparing medicament for preventing and controlling myocardial hypertrophy, hypertrophic cardiomyopathy and chronic heart failure

A technology for hypertrophic cardiomyopathy and chronic heart failure, which is applied to drugs for hypertrophic cardiomyopathy and chronic heart failure. In the field of preparation and prevention of myocardial hypertrophy, the traditional Chinese medicine Scrophulariaceae can inhibit the activity of the renin-angiotensin-aldosterone system and improve life. Quality, the effect of inhibiting the continuous excitation of sympathetic nerves

Inactive Publication Date: 2010-12-01
SHANGHAI UNIV OF T C M
View PDF0 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, there is no report on the prevention and treatment of ventricular remodeling, myocardial hypertrophy and chronic heart failure

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Application of radix scrophulariae in preparing medicament for preventing and controlling myocardial hypertrophy, hypertrophic cardiomyopathy and chronic heart failure
  • Application of radix scrophulariae in preparing medicament for preventing and controlling myocardial hypertrophy, hypertrophic cardiomyopathy and chronic heart failure
  • Application of radix scrophulariae in preparing medicament for preventing and controlling myocardial hypertrophy, hypertrophic cardiomyopathy and chronic heart failure

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

Embodiment 2

Embodiment 3

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention belongs to the traditional Chinese pharmaceutics field, and relates to an application of traditional Chinese medicine radix scrophulariae to the preparation of a drug for preventing and curing cardiac hypertrophy, hypertrophic cardiomyopathy and chronic heart failure. The invention researches the effect of the cardiac hypertrophy and ventricle reconstruction model of a plurality of mice and rats on the traditional Chinese medicine radix scrophulariae. The experimental results show that the radix scrophulariae water or the alcohol abstracts has evident function for preventing thecardiac hypertrophy, the ventricular remodeling and the chronic heart failure caused by various reasons, the mechanism is obviously related with the excessive activation of the neuroendocrine system such as a suppressing renin-angiotensin-aldosterone system and is related with the functions of blood pressure reduction, heart beat slowing and hemodynamics improvement. The figwort can be used for preparing the drug for preventing the diseases of cardiac hypertrophy, hypertrophic cardiomyopathy and chronic heart failure and for reducing the possibility of the incidence rate of arrhythmia and the sudden death of patients with cardiac hypertrophy, hypertrophic cardiomyopathy and chronic heart failure.

Description

Application of Radix Scrophulariae in Preparation of Medicines for Prevention and Treatment of Myocardial Hypertrophy, Hypertrophic Cardiomyopathy and Chronic Heart Failure technical field The invention belongs to the field of traditional Chinese medicine pharmacy, and relates to the use of traditional Chinese medicine Scrophulariaceae in the preparation of medicines for preventing and treating ventricular remodeling, in particular to the use of Chinese medicine Scrophulariaceae in the preparation and prevention of myocardial hypertrophy, hypertrophic cardiomyopathy and chronic heart failure. Uses in medicine. Background technique Chronic cardiac insufficiency, also known as congestive heart failure (CHF), is a clinical syndrome in which the heart pumping function is reduced due to various etiologies and cannot discharge enough blood to meet the metabolic needs of tissues and organs throughout the body. very high. In the past, the clinical treatment of CHF focused on the...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/808A61P9/04A61P9/00
Inventor 陈长勋顾伟梁金若敏王樱
Owner SHANGHAI UNIV OF T C M
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products