221 results about "Resonance spectrum" patented technology

A method for acquiring an image or spectrum of a subject or object residing within the magnetic field of a magnetic resonance apparatus, comprises the steps of:executing a predetermined pulse sequence for applying gradient magnetic fields and for coupling in electromagnetic excitation pulses to induce nuclear magnetic resonance within the subject or object;detecting an electromagnetic signal resulting from said magnetic resonance; andconstructing at least one image or magnetic resonance spectrum of said subject or object from said detected electromagnetic signal.According to the invention, said coupling in of the electromagnetic excitation pulse and / or said detecting of the electromagnetic signal are carried out substantially by means of travelling electromagnetic waves.

The invention concerns a superconducting high-field magnet system (1) for a high-resolution magnetic resonance spectrometer, comprising a magnet coil (4) which is superconductingly short-circuited during operation, and generates a homogeneous temporally stable magnetic field during operation that meets the requirements for taking a high-resolution magnetic resonance spectrum. The magnet coil (4) comprises an LTS partial coil (4b, 4c) and an HTS partial coil (4a, 4d). The LTS partial coil (4b, 4c) can be separately short-circuited in a pure LTS circuit (14b) via an LTS switch (15b), and the HTS partial coil (4a, 4d) can be separately short-circuited in a pure HTS circuit (14) via an HTS switch (15a) and both partial coils (4a, 4d; 4b, 4c) are connected via an LTS-HTS joint (20) and are charged by the same power supply.

The invention relates to a method which is developed on the basis of the impacts of biological molecules on the single nanoparticle localized surface plasmon resonance effect and uses a localized surface plasmon resonance spectrum for detecting biological molecules, thereby solving the controllable preparation of the nanoparticle and eliminating non-specific absorption and parasitic light signalsduring the detection on the basis of positioning, orienteering, being coupled with a microfluidic system and optimizing a signal collection region in a micro-channel. The invention comprises the stepsof using the vapor deposition technology and the advanced preparation technology of micro-nano materials and structures to prepare the identifiable signal nanoparticle or a particle array in a micro-fluid, integrating the single nanoparticle or the particle array in the micro-channel, further modifying and functionalizing the surface thereof and using an optical signal generated by the impacts ofthe biological molecules on the nanoparticle localized surface plasmon resonance effect for detecting the type and the concentration of the biological molecules in the fluid. Therefore, a high-yieldsuper-sensitive chip-based biological molecule detector is constructed in the micro-channel.

The reaction of N-alkylimidazol with alkyl sulfonates, at room temperature, favors the production of 1,3-dialkylimidazolium alkane-sulfonates as crystalline solids at high yields. The alkane-sulfonate anions may be easily substituted by a series of other anions [BF4, PF6, PF3(CF2CF3)3, CF3SO3 and (CF3SO2)2N] through simple anion, salt, or acid reactions in water at room temperature. The extraction with dichloromethane, filtration, and evaporation of the solvent, allows the production of the desired ionic liquids at a yield of 80-95%. The purity of these ionic liquids (in some cases >99.4%) is performed using the intensity of 13C satellite signals from the magnetic resonance spectrums of the N-methyl imidazolium group as an internal standard.

The invention relates to a detection optical fiber based on a surface plasma resonance principle and a sensor. The surface plasma resonance detection optical fiber comprises a fiber core and air holes arranged on the axial direction of the fiber core and is characterized in that the first air hole of a solution channel for detecting is positioned in the center of the cross section of the optical fiber; the inner wall of the first air hole is plated with a metal film; a sensing material is plated on the inner surface of the metal film; N second air holes are distributed in the fiber core and at the periphery of the first air hole uniformly and respectively; N is an integer of more than 1; and the connecting line of the central points of the N air holes is shaped like a regular N-side polygon. According to the detection, mutual influence among the conventional channels of various samples is avoided, the resonance spectrum is narrow, and the signal to noise ratio is high. The sensor breaks through the limit that the refractive index detection upper limit of the conventional similar sensor is less than 1.42 and can effectively detect the chemical organic solution with high refractive index.

The invention discloses a quick reconstruction method for under-sampling magnetic resonance spectra, and relates to magnetic resonance spectra. The method comprises the steps of firstly, performing under-sampling on time domain signals of magnetic resonance spectra, and filling a Hankel matrix with sampling data; then reconstructing complete time domain signals by using the low rank characteristic of the matrix, and performing Fourier transformation to obtain high-quality spectra, wherein in the process, the minimization of a matrix nuclear norm item is approached by using a matrix factorization method and minimizing a matrix Frobenius norm item, so that singular value decomposition used when the nuclear norm item is solved is avoided, and the effect of accelerating reconstruction is achieved. The method is excellent in effect and easy to operate, and can be applied to under-sampling magnetic resonance spectrum reconstruction of one, two and higher dimensions.

The invention discloses a prism SPR sensor detection system based on P-polarized light, which belongs to the technical field of the prism SPR sensor systems. The prism SPR sensor detection system orderly consists of a light source (1), a multimode optical fiber (2), a prism SPR sensor (4), a convex lens (5), a spectrometer (7) which receives rays transmitted by the convex lens (5) through a multimode optical fiber (6), and a computer (9) connected with the spectrometer (7). The prism SPR sensor detection system is characterized in that a polarization splitting prism (3) with a splitting bandwidth of between 40 and 1000nm is also arranged between the light source (1) and the prism SPR sensor (4). The method ensures that the half-wave widths of resonance wave troughs in a spectrum are reduced, more contributes to the analysis and detection of resonant wavelength parameters in a wavelength modulation method, and is also favorable for improving adhesion phenomenon of various resonance wave troughs of a resonance spectrum detected by a prism distributed measurement system. The prism SPR sensor detection system has the characteristics of simple light path, narrow resonance wave troughs, high detection accuracy, and so on.

The invention provides a breast tumor diagnosis system based on magnetic resonance spectrum imaging, comprising a superconduction MR (Magneto Resistance) scanner and a computer system. Through a computer auxiliary detection measure, the breast tumor diagnosis system realizes the early identification diagnosis of a breast tumor and the further diagnosis of breast cancer. Mammary gland magnetic resonance spectrum data are studied by adopting a distinctive manifold study method and projected to a low dimension embedding space, thus not only a low dimension manifold structure hidden in a high dimension magnetic resonance spectrum space can be revealed, but also the identification information in the mammary gland magnetic resonance spectrum data can be efficiently kept; then optimization clustering is carried out on the low dimension identification characteristic by utilizing a clustering method so that data points without the similar identification characteristic are separated to the maximum; and further a cost sensitive mechanism is introduced to achieve misclassification total cost minimization and realize optimization diagnosis of the breast cancer.

The invention discloses an optical waveguide immunosensor and a detection method thereof. The optical waveguide immunosensor basically comprises an optical waveguide resonator cavity, a magnetic needle and an immunologic reaction tank. The method comprises the following steps of: carrying out surface specificity modification to nano magnetic particles; capturing a substance to be detected by utilizing an antibody-antigen reaction; orderly limiting the nano magnetic particles on the surface of the circular or disc-shaped optical waveguide resonator cavity by utilizing the magnetic needle; sensing refraction index change before and after an immunologic reaction by utilizing an evanescent field; and analyzing corresponding resonance spectrum change to acquire the content of the substance to be detected in a sample. The optical waveguide immunosensor has simple structure. Based on the circular or disc-shaped optical waveguide resonator cavity with compact structure, the nano particles after immunologic specificity modification are absorbed to the optical waveguide surface by the magnetic needle to measure the offset of a resonance frequency and accurately and sensitively detect the immunologic reaction, and the device can be repeatedly used so that the invention has favorable application prospects.

The invention discloses a magnetic resonance spectrum reconstruction method based on a block Hankel matrix. The method comprises the following steps: firstly acquiring a magnetic resonance signal under-sampling template, constructing a block Hankel matrix of a two-dimensional matrix, and establishing a low-rank reconstruction model based on the block Hankel matrix of a magnetic resonance free attenuation signal; and then solving the reconstruction model through an iteration algorithm and acquiring a reconstructed free attenuation signal; and finally performing the Fourier transform to obtain a complete magnetic resonance spectrum. The reconstruction method disclosed by the invention is small in required sampling data amount, high in precision, and capable of reconstructing a complete magnetic resonance spectrum from less under-sampling data; the sampling speed of the method provided by the invention is faster than that of the existing method under the condition of obtaining the reconstructed spectrum data with the same quality.

The invention discloses a magnetic resonance spectrum reconstruction method based on deep learning, and relates to a magnetic resonance spectrum reconstruction method. The method includes: Generatinga time domain signal of the magnetic resonance spectrum by utilizing an exponential function; Establishing a training set of the under-sampling time domain signals and the full-sampling spectrum; Designing a convolutional neural network in the data verification convolutional neural network structure; Designing a bottleneck layer in the data verification convolutional neural network structure; Designing a data verification layer in the data verification convolutional neural network structure; Designing a feedback function in a data verification convolutional neural network structure; Establishing a data verification convolutional neural network structure as a spectrum reconstruction model; Training network optimization parameters; Reconstructing an under-sampling magnetic resonance time domain signal of the target; When undersampling operation is carried out in the time-frequency domain, utilizing the strong fitting capability of the convolutional neural network and the data verification capability of the data verification layer to complete rapid and high-quality reconstruction of the undersampling magnetic resonance spectrum signal.

The present invention discloses a probe micro displacement sensing system based on a surface nanoscale axial photonics (SNAP) structure echo wall microcavity. The system comprises a tuning laser, a polarization controller, a coupling waveguide, a photoelectric detector, an SNAP structure microcavity and a displacement device. The tuning laser generates a sweep frequency laser which enters the SNAPstructure microcavity through the polarization controller and the coupling waveguide, and the photoelectric detector is configured to obtain a resonance spectrum. The system achieves axial micro displacement sensing of the microcavity through monitoring of a Q value and transmittance of a resonant mode to effectively reduce the influence of external environment factors such as temperature fluctuation for sensing precision, and the SNAP structure microcavity is small in volume, light in weight and easy to package and integration so as to facilitate probe measurement.

The invention discloses a petroleum drilling fluid nuclear magnetic resonance while-drilling analytic method which is characterized in that the method comprises the following steps of: sampling, serial sampling is respectively carried out at a drilling fluid inlet and at a drilling fluid outlet; map collection, relaxation maps of 1 H and 13 C are drawn; map transformation, the two relaxation maps are processed by pulse fourier transformation to form a rameau frequency spectrum; differential spectrum processing, a stratum fluid resonance spectrum is obtained; the synthesized geological interpretation is carried out, and a map library is established; a synthesized interpretation map is drawn up; the related data in a logging database, a 1H nuclear magnetic resonance map and a 13C nuclear magnetic resonance map are combined to form a petroleum drilling fluid nuclear magnetic resonance while-drilling analytic map. The method has the obvious effects that the drilling fluid is continously and quickly analyzed in an oil drilling field on line; and the characteristics of the stratum fluid carried over in the drilling fluid is determined; the characteristics of the stratum fluid can be precisely judged in the while-drilling process without needing sampling the contents of oil gas in a core or rock debris; and the method is suitable for the requirements of the modern drilling technique.

Described is a method for examining a surface of a sample using an atomic force scanning microscope (AFM) comprising a cantilever with a longitudinal extension along which a measuring tip is disposed, which is selectively arranged relative to said sample surface by a driver means and whose spatial position is detected using a sensor unit, and said microscope is provided with at least one ultrasound generator, which initiates vibration excitation at a given excitation frequency between said sample surface and said cantilever, the measuring tip of which is brought into contact with said sample surface in such a manner that said measuring tip is excited to vibrations which are oriented lateral to said sample surface and perpendicular to said longitudinal extension of said cantilever and that the torsional vibrations induced in said cantilever are detected and analyzed by means of an evaluation unit. The invention is distinguished in that the vibration excitation occurs in such a manner that the oscillations executed by the measuring tip have higher harmonic vibration parts relative to the excitation frequency, that vibration excitation is conducted at excitation amplitudes which lead inside the cantilever to torsional amplitudes, the maximum values of which form a largely constant plateau value despite increasing excitation amplitudes and the resonance spectra of which undergo, in the range of the maximum values of the torsional amplitudes, a widening of the resonance spectrum which is determinable by a plateau width, and that used for examining the sample surface are the resonance spectra, preferably the plateau value, the plateau width and / or the gradient of the respective resonance spectra.

A method for examining a surface of a sample is described using an atomic force scanning microscope (AFM) comprising a cantilever with a longitudinal extension along which a measuring tip is disposed, which is selectively arranged relative to the sample surface by a means for driving and whose spatial position is detected using a sensor unit. Vibration excitation is conducted at excitation amplitudes which produce inside the cantilever torsional amplitudes with maximum values which form a largely (substantively) constant plateau value despite increasing excitation amplitudes and the resonance spectra, in a range of maximum values of the torsional amplitudes, a widening of the resonance spectrum which is determinable by a plateau width. The resonance spectra, preferably the plateau value, the plateau width and / or the gradient of the respective resonance spectra are used for examining the sample.

The invnetion provides fluoroposphate glass, precision press molding preform, optical element blank, optical element and method of manufacturing the same. A fluorophosphate glass of the invention contains 30 to 50 cationic % of a phosphorus ingredient in terms of P5+, the glass having, in a nuclear magnetic resonance spectrum, a resonance spectrum which is generated near a reference frequency of 31P and has a shape of Gaussian function. The glass of the invention is reduced in volatility and erosiveness.

The invention relates to a porcine lactobacillus reuteri lyophilized preparation and a preparation method thereof, belonging to the field of application of microbes. The porcine lactobacillus reuteri lyophilized preparation is characterized in that a protective agent in the lyophilized preparation comprises the following ingredients in percentage by weight: 10 percent of skimmed milk, 0.1 percent of sodium glutamate, 0.3 percent of cysteine, 10 percent of fucose, 8 percent of lactose, 10 percent of dextrine and the balance of water. Proved by experiments, the porcine lactobacillus reuteri lyophilized preparation of the invention can increase the viable lactobacillus content in nursery pig feces, can reduce the content of colon bacillus, and has the effect of improving the average daily gain and immunity of the nursery pigs. The lyophilized preparation prepared by the method of the invention has the viable bacteria count not less than 109cfu / g, and the viable bacteria survival rate is higher than 75 percent after the lyophilized preparation is stored for 90 days. The invention also provides an optimized culture medium for lactobacillus reuteri, and the viable bacteria count is six times higher than that that of the viable bacteria cultured on the conventional culture medium (Magnetic Resonance Spectrum (MRS) culture medium).

The present invention provides a method for determining the diffusion coefficient of carbon dioxide in a porous medium. The method comprises: sealing all surfaces of rock core saturated with crude oil; placing the sealed rock core in a diffusion cylinder; heating the diffusion cylinder to achieve a desired temperature, and maintain the constant temperature; opening a valve, pressurizing a carbon dioxide container to achieve a desired pressure, and maintaining the constant pressure; opening a valve, and injecting CO2 into the diffuser cylinder under the constant pressure; measuring the rock core in the diffusion cylinder through a nuclear magnetic resonance system to obtain a T2 spectrum; calculating the volume proportions of the CO2 and the crude oil in the rock core by using the peak area in the T2 spectrum; and calculating the molar concentration of the CO2 in the rock core, calculating the molar concentration C of the CO2 in the rock core under different diffusion time conditions to obtain an average concentration C<->, and substituting the average concentration C<-> into a formula defined in the specification to obtain the diffusion coefficient D. According to the present invention, with the method, the visualized calculation and the quantitative analysis of the diffusion coefficient by using the T2 magnetic resonance spectrum is achieved.

A method of performing spatially localized magnetic resonance spectroscopy includes receiving a magnetic resonance image of an object; identifying a plurality C of compartments that generate magnetic resonance spectroscopy signals in the object including at least one compartment of interest; segmenting in at least one spatial dimension the magnetic resonance image of the object into the C compartments; acquiring magnetic resonance spectroscopy signals from the compartments by applying a plurality of M′ phase encodings applied in the at least one spatial dimension, wherein M′≧C; calculating a spatially localized magnetic resonance chemical shift spectrum from the at least one compartment of interest; and rendering a spatially localized magnetic resonance spectrum that is substantially equal to a spatial average of magnetic resonance chemical shift spectra from the at least one compartment of interest. A magnetic resonance spectroscopy and imaging system is configured to perform the above method.

The invention provides an exponential signal denoising method achieved by means of prior information and relates to a denoising method for exponential signals.The prior exponential signals form a Hankel matrix according to a set sequence, the Hankel matrix is subjected to singular value decomposition, and a prior signal space and a prior singular value are obtained; then a Hankel matrix with the same size as the former Hankel matrix is established for the target exponential signals, and the matrix of the target signals is decomposed through the prior information space; after a weighted threshold is obtained from the prior singular value, a Hankel matrix of the denoised target signals is obtained from the singular value of the target exponential signals according to the weighted threshold; then the Hankel matrix of the target signals is solved, and finally the denoised signals are obtained.Through the prior information of the reference signals, the speed is high, the effect is good, and operation is easy.Denoising of a magnetic resonance spectrum can be achieved for signals with exponential features such as time domain signals of the magnetic resonance spectrum through the method, and the purposes of shortening the sampling time and increasing the signal to noise ratio of the spectrum are achieved.

The system describes a means and a method for stabilizing the magnetic field generated in the measuring volume of a high-resolution magnetic resonance spectrometer having an actively shielded magnet coil (4) which is located in a cryostat (2) and which is superconductingly short-circuited. The system comprises a compensation coil (12) which is decoupled from the magnet coil (4), and is disposed on the shielding coil (4b) of the magnet coil (4).

Provided is a magnetic resonance imaging system capable of reducing degradation in a magnetic resonance spectrum derived from a change in a static magnetic field. A sequence controller performs non-water-suppressed spectrum measurement (pre-scan) cyclically during water-suppressed spectrum measurement (main scan) accompanied by repetitive measurement intended for averaging of signals, and cyclically detects a water resonant frequency (water-signal peak position) and a phase value at a water-signal peak from an obtained non-water-suppressed spectrum (the cyclic pre-scan makes it possible to sense a time-varying rate of static magnetic field strength (resonant frequency)). For the water-suppressed spectrum measurement (main scan) succeeding the pre-scan, a reception-initiating phase value that is used to detect a magnetic resonance signal is set to a value calculated using the phase value at the water-signal peak position detected during the pre-scan. For averaging of measured magnetic resonance signals, data items are shifted by the value calculated from the phase value at the water-signal peak position detected during the pre-scan. Thereafter, the averaging is carried out.

The invention relates to an optical fiber surface plasma wave nucleic acid sensor and method for detecting polymorphism of nucleotide. The system includes wideband lamp house, P type Polaroid, gamma type optical fiber coupler, coupler interface, sensing optical fiber, detector of terminal reflective optical fiber surface plasma wave resonance biology sensor, spectrum device and computer. The invention uses terminal reflective optical fiber surface plasma wave nucleic sensor detector and distributed optical fiber surface plasma wave nucleic sensor detector to realize the detection of polymorphism of nucleotide. Compared with spectrum detection method, the accurate value of resonance spectrum wavelength of the surface plasma wave can be acquired. The invention needs not to be signed, and it has no damage to the sample.

The invention discloses a rapid super-complex magnetic resonance spectrum reconstruction method, relates to magnetic resonance spectrums, and provides a method for reconstructing complete magnetic resonance spectrums from under-sampled super-complex magnetic resonance spectrums. The method comprises the following steps of: firstly filling an obtained under-sampled super-complex magnetic resonance spectrum into a blocked Hankel matrix; converting the super-complex blocked Hankel matrix into a super-complex companion matrix; constructing a reconstruction model, a nuclear norm of which corresponding to the super-complex companion matrix is minimized; and finally solving the reconstruction model by adoption of a rapid algorithm, so as to obtain a complete magnetic resonance spectrum.

Spectral scanning magnetic resonance imaging methods and systems. In preferred methods and systems of the invention, to measure the resonance spectrum of the target object, a plurality of excitation signals in different frequencies and / or waveform shapes are introduced simultaneously to the imaging volume through one or more excitation coils, and the response spectrum is measured also in real-time and / or after excitation. Systems of the invention can be compact and portable, with small magnets providing the deterministic inhomogeneous magnetic field. Preferred embodiments include integrated circuit transmitters and receivers. Preferred systems of the invention are suitable, for example, for point of care medical diagnostics.

The invention relates to the technical field of optical fiber magnetic field sensor, and specifically discloses a vector magnetic field sensor based on side-polished fiber surface plasmon resonance and a manufacturing and detection method thereof. The vector magnetic field sensor comprises a side-polished fiber, a metal film plated on a polishing zone, a magnetic fluid, a light source, and a spectrometer for detecting a transmission spectrum. The polished fiber is made by polishing a part of the cladding and the core of an optical fiber, and is provided with a glass capillary and an optical UVglue. The magnetic fluid is wrapped in seal around the polished fiber via the glass capillary and the optical UV glue. The invention utilizes the surface plasmon resonance (SPR) effect to form a resonance trough (the lowest transmitted light intensity) in the transmission spectrum. In the different magnetic field strengths or magnetic field directions, the refractive index of the magnetic fluid above the metal film is different, which results in the difference of the SPR resonance trough position. The sensing characteristics of the sensor on the direction and intensity of the magnetic field can be calibrated by recording the drift of the resonance spectrum.

The invention discloses a single-frequency narrow-band optical fiber laser based on a high roundness three-dimensional rotational symmetric microcavity. The laser comprises a semiconductor laser pumping source, a wavelength division multiplexer, an optical isolator, a rare earth doped fiber, a polarization controller, an optical coupler and a high roundness microballoon cavity-conical fiber coupling unit. The semiconductor laser pumping source is connected with the optical isolator through the wavelength division multiplexer, and is connected with the rare earth doped fiber through the output end of the optical isolator. The output end of the rare earth doped fiber passes through the polarization controller, the high roundness microballoon cavity-conical fiber coupling unit and the optical coupler in order, and finally is connected with the input end of the wavelength division multiplexer through the output end of the optical coupler to form a closed cavity. According to the invention, high roundness microballoon cavity-conical fiber coupling unit is used to select the frequency; through ultra-narrow bandwidth echo wall mold resonance spectrum formed in the high roundness microballoon cavity, the output laser has the advantages of ultra-narrow bandwidth; and the laser has the advantages of great coherence, high stability, compact structure, low cost, small loss and the like.

The invention discloses a method for suppressing the mechanical resonance of a cutting machine servo system. After the online mechanical resonance automatic suppression function of a glass cutting machine servo system is started, a speed control loop samples the quadrature-axis current signal of an X-axis servo motor, and when the number of sampling points is equal to a predetermined point number,starts data operation which mainly includes calculation of signal spectrum, storage of spectrum in a reverse order, calculation of spectrum amplitude, and parameter configuration of a notch filter. The system, after automatically configuring the parameters of the notch filter according to the resonant frequency detected online, can suppress mechanical resonance while maintaining high gain and high stiffness control, ensures the spectrum analysis of the quadrature-axis current feedback signal when the servo system resonates, and detects the resonance spectrum characteristics of the system in real time. The adaptive notch filter is designed based on the detection result of the resonance spectrum characteristic and the parameters of the notch filter are automatically set, which suppresses the mechanical resonance of the cutting machine servo system.