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217 results about "Resonance spectrum" patented technology

Preparation process of single nanoparticle and array-based biological molecule detector thereof

The invention relates to a method which is developed on the basis of the impacts of biological molecules on the single nanoparticle localized surface plasmon resonance effect and uses a localized surface plasmon resonance spectrum for detecting biological molecules, thereby solving the controllable preparation of the nanoparticle and eliminating non-specific absorption and parasitic light signalsduring the detection on the basis of positioning, orienteering, being coupled with a microfluidic system and optimizing a signal collection region in a micro-channel. The invention comprises the stepsof using the vapor deposition technology and the advanced preparation technology of micro-nano materials and structures to prepare the identifiable signal nanoparticle or a particle array in a micro-fluid, integrating the single nanoparticle or the particle array in the micro-channel, further modifying and functionalizing the surface thereof and using an optical signal generated by the impacts ofthe biological molecules on the nanoparticle localized surface plasmon resonance effect for detecting the type and the concentration of the biological molecules in the fluid. Therefore, a high-yieldsuper-sensitive chip-based biological molecule detector is constructed in the micro-channel.
Owner:宋玉军

Optical waveguide immunosensor and detection method thereof

The invention discloses an optical waveguide immunosensor and a detection method thereof. The optical waveguide immunosensor basically comprises an optical waveguide resonator cavity, a magnetic needle and an immunologic reaction tank. The method comprises the following steps of: carrying out surface specificity modification to nano magnetic particles; capturing a substance to be detected by utilizing an antibody-antigen reaction; orderly limiting the nano magnetic particles on the surface of the circular or disc-shaped optical waveguide resonator cavity by utilizing the magnetic needle; sensing refraction index change before and after an immunologic reaction by utilizing an evanescent field; and analyzing corresponding resonance spectrum change to acquire the content of the substance to be detected in a sample. The optical waveguide immunosensor has simple structure. Based on the circular or disc-shaped optical waveguide resonator cavity with compact structure, the nano particles after immunologic specificity modification are absorbed to the optical waveguide surface by the magnetic needle to measure the offset of a resonance frequency and accurately and sensitively detect the immunologic reaction, and the device can be repeatedly used so that the invention has favorable application prospects.
Owner:SUZHOU INST OF BIOMEDICAL ENG & TECH

A magnetic resonance spectrum reconstruction method based on deep learning

The invention discloses a magnetic resonance spectrum reconstruction method based on deep learning, and relates to a magnetic resonance spectrum reconstruction method. The method includes: Generatinga time domain signal of the magnetic resonance spectrum by utilizing an exponential function; Establishing a training set of the under-sampling time domain signals and the full-sampling spectrum; Designing a convolutional neural network in the data verification convolutional neural network structure; Designing a bottleneck layer in the data verification convolutional neural network structure; Designing a data verification layer in the data verification convolutional neural network structure; Designing a feedback function in a data verification convolutional neural network structure; Establishing a data verification convolutional neural network structure as a spectrum reconstruction model; Training network optimization parameters; Reconstructing an under-sampling magnetic resonance time domain signal of the target; When undersampling operation is carried out in the time-frequency domain, utilizing the strong fitting capability of the convolutional neural network and the data verification capability of the data verification layer to complete rapid and high-quality reconstruction of the undersampling magnetic resonance spectrum signal.
Owner:XIAMEN UNIV

Petroleum drilling fluid nuclear magnetic resonance while-drilling analytic

The invention discloses a petroleum drilling fluid nuclear magnetic resonance while-drilling analytic method which is characterized in that the method comprises the following steps of: sampling, serial sampling is respectively carried out at a drilling fluid inlet and at a drilling fluid outlet; map collection, relaxation maps of 1 H and 13 C are drawn; map transformation, the two relaxation maps are processed by pulse fourier transformation to form a rameau frequency spectrum; differential spectrum processing, a stratum fluid resonance spectrum is obtained; the synthesized geological interpretation is carried out, and a map library is established; a synthesized interpretation map is drawn up; the related data in a logging database, a 1H nuclear magnetic resonance map and a 13C nuclear magnetic resonance map are combined to form a petroleum drilling fluid nuclear magnetic resonance while-drilling analytic map. The method has the obvious effects that the drilling fluid is continously and quickly analyzed in an oil drilling field on line; and the characteristics of the stratum fluid carried over in the drilling fluid is determined; the characteristics of the stratum fluid can be precisely judged in the while-drilling process without needing sampling the contents of oil gas in a core or rock debris; and the method is suitable for the requirements of the modern drilling technique.
Owner:重庆奥能瑞科石油技术有限责任公司

Method for determining tribological properties of a sample surface using a scanning microscope (sem) and associated scanning microscope

Described is a method for examining a surface of a sample using an atomic force scanning microscope (AFM) comprising a cantilever with a longitudinal extension along which a measuring tip is disposed, which is selectively arranged relative to said sample surface by a driver means and whose spatial position is detected using a sensor unit, and said microscope is provided with at least one ultrasound generator, which initiates vibration excitation at a given excitation frequency between said sample surface and said cantilever, the measuring tip of which is brought into contact with said sample surface in such a manner that said measuring tip is excited to vibrations which are oriented lateral to said sample surface and perpendicular to said longitudinal extension of said cantilever and that the torsional vibrations induced in said cantilever are detected and analyzed by means of an evaluation unit. The invention is distinguished in that the vibration excitation occurs in such a manner that the oscillations executed by the measuring tip have higher harmonic vibration parts relative to the excitation frequency, that vibration excitation is conducted at excitation amplitudes which lead inside the cantilever to torsional amplitudes, the maximum values of which form a largely constant plateau value despite increasing excitation amplitudes and the resonance spectra of which undergo, in the range of the maximum values of the torsional amplitudes, a widening of the resonance spectrum which is determinable by a plateau width, and that used for examining the sample surface are the resonance spectra, preferably the plateau value, the plateau width and / or the gradient of the respective resonance spectra.
Owner:FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG EV

Porcine lactobacillus reuteri lyophilized preparation and preparation method thereof

The invention relates to a porcine lactobacillus reuteri lyophilized preparation and a preparation method thereof, belonging to the field of application of microbes. The porcine lactobacillus reuteri lyophilized preparation is characterized in that a protective agent in the lyophilized preparation comprises the following ingredients in percentage by weight: 10 percent of skimmed milk, 0.1 percent of sodium glutamate, 0.3 percent of cysteine, 10 percent of fucose, 8 percent of lactose, 10 percent of dextrine and the balance of water. Proved by experiments, the porcine lactobacillus reuteri lyophilized preparation of the invention can increase the viable lactobacillus content in nursery pig feces, can reduce the content of colon bacillus, and has the effect of improving the average daily gain and immunity of the nursery pigs. The lyophilized preparation prepared by the method of the invention has the viable bacteria count not less than 109cfu/g, and the viable bacteria survival rate is higher than 75 percent after the lyophilized preparation is stored for 90 days. The invention also provides an optimized culture medium for lactobacillus reuteri, and the viable bacteria count is six times higher than that that of the viable bacteria cultured on the conventional culture medium (Magnetic Resonance Spectrum (MRS) culture medium).
Owner:BEIJING ACADEMY OF AGRICULTURE & FORESTRY SCIENCES

Method for determining diffusion coefficient of carbon dioxide in porous medium

The present invention provides a method for determining the diffusion coefficient of carbon dioxide in a porous medium. The method comprises: sealing all surfaces of rock core saturated with crude oil; placing the sealed rock core in a diffusion cylinder; heating the diffusion cylinder to achieve a desired temperature, and maintain the constant temperature; opening a valve, pressurizing a carbon dioxide container to achieve a desired pressure, and maintaining the constant pressure; opening a valve, and injecting CO2 into the diffuser cylinder under the constant pressure; measuring the rock core in the diffusion cylinder through a nuclear magnetic resonance system to obtain a T2 spectrum; calculating the volume proportions of the CO2 and the crude oil in the rock core by using the peak area in the T2 spectrum; and calculating the molar concentration of the CO2 in the rock core, calculating the molar concentration C of the CO2 in the rock core under different diffusion time conditions to obtain an average concentration C<->, and substituting the average concentration C<-> into a formula defined in the specification to obtain the diffusion coefficient D. According to the present invention, with the method, the visualized calculation and the quantitative analysis of the diffusion coefficient by using the T2 magnetic resonance spectrum is achieved.
Owner:CHINA PETROLEUM & CHEM CORP +1

Exponential signal denoising method achieved by means of prior information

The invention provides an exponential signal denoising method achieved by means of prior information and relates to a denoising method for exponential signals.The prior exponential signals form a Hankel matrix according to a set sequence, the Hankel matrix is subjected to singular value decomposition, and a prior signal space and a prior singular value are obtained; then a Hankel matrix with the same size as the former Hankel matrix is established for the target exponential signals, and the matrix of the target signals is decomposed through the prior information space; after a weighted threshold is obtained from the prior singular value, a Hankel matrix of the denoised target signals is obtained from the singular value of the target exponential signals according to the weighted threshold; then the Hankel matrix of the target signals is solved, and finally the denoised signals are obtained.Through the prior information of the reference signals, the speed is high, the effect is good, and operation is easy.Denoising of a magnetic resonance spectrum can be achieved for signals with exponential features such as time domain signals of the magnetic resonance spectrum through the method, and the purposes of shortening the sampling time and increasing the signal to noise ratio of the spectrum are achieved.
Owner:XIAMEN UNIV

Vector magnetic field sensor based on side-polished fiber surface plasmon resonance and manufacturing and detection method thereof

The invention relates to the technical field of optical fiber magnetic field sensor, and specifically discloses a vector magnetic field sensor based on side-polished fiber surface plasmon resonance and a manufacturing and detection method thereof. The vector magnetic field sensor comprises a side-polished fiber, a metal film plated on a polishing zone, a magnetic fluid, a light source, and a spectrometer for detecting a transmission spectrum. The polished fiber is made by polishing a part of the cladding and the core of an optical fiber, and is provided with a glass capillary and an optical UVglue. The magnetic fluid is wrapped in seal around the polished fiber via the glass capillary and the optical UV glue. The invention utilizes the surface plasmon resonance (SPR) effect to form a resonance trough (the lowest transmitted light intensity) in the transmission spectrum. In the different magnetic field strengths or magnetic field directions, the refractive index of the magnetic fluid above the metal film is different, which results in the difference of the SPR resonance trough position. The sensing characteristics of the sensor on the direction and intensity of the magnetic field can be calibrated by recording the drift of the resonance spectrum.
Owner:JINAN UNIVERSITY

Single-frequency narrow-band optical fiber laser based on high roundness three-dimensional rotational symmetric microcavity

The invention discloses a single-frequency narrow-band optical fiber laser based on a high roundness three-dimensional rotational symmetric microcavity. The laser comprises a semiconductor laser pumping source, a wavelength division multiplexer, an optical isolator, a rare earth doped fiber, a polarization controller, an optical coupler and a high roundness microballoon cavity-conical fiber coupling unit. The semiconductor laser pumping source is connected with the optical isolator through the wavelength division multiplexer, and is connected with the rare earth doped fiber through the output end of the optical isolator. The output end of the rare earth doped fiber passes through the polarization controller, the high roundness microballoon cavity-conical fiber coupling unit and the optical coupler in order, and finally is connected with the input end of the wavelength division multiplexer through the output end of the optical coupler to form a closed cavity. According to the invention, high roundness microballoon cavity-conical fiber coupling unit is used to select the frequency; through ultra-narrow bandwidth echo wall mold resonance spectrum formed in the high roundness microballoon cavity, the output laser has the advantages of ultra-narrow bandwidth; and the laser has the advantages of great coherence, high stability, compact structure, low cost, small loss and the like.
Owner:NANJING UNIV OF POSTS & TELECOMM

Magnetic resonance spectrum noise reduction method based on neural network

The invention discloses a magnetic resonance spectrum noise reduction method based on a neural network, and relates to a magnetic resonance spectrum noise reduction method. The method comprises the following steps of: 1) averaging different combinations acquired for multiple times to construct a corresponding training model data set and a label set for solving a mapping relationship between a highsignal-to-noise ratio magnetic resonance spectrum and a low signal-to-noise ratio magnetic resonance spectrum; 2) constructing a deep learning network model for magnetic resonance spectrum noise reduction based on a long-short-term memory recurrent neural network of an iterative sliding window; 3) training the deep learning network model designed in the step 2) by using the data set generated inthe step 1), and training the parameters of the network in the step 2) by using an ADAM optimization algorithm to obtain the optimal parameters of the model; and 4) performing noise reduction processing on the time domain signal of the magnetic resonance spectrum with low signal-to-noise ratio by using the network model trained in the step 3), and performing Fourier transform on the time domain signal after noise reduction to obtain a corresponding magnetic resonance spectrum after noise reduction. The invention has the characteristics of no need of priori knowledge, high noise reduction speed, high noise reduction quality and good generalization, and is suitable for dense spectral peak noise reduction.
Owner:XIAMEN UNIV
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