Stable type povidone iodine disinfectant and preparation method thereof

Abstract

The invention relates to an iodine-containing disinfectant, in particular to a povidone iodine disinfectant and a preparation method thereof. The povidone iodine disinfectant is a stable type povidone iodine disinfectant which contains the following components according to percentage by weight (wt percent): 8.0 to 13.0 percent of the PVP-I, 0.5 to 1.0 percent of KIO3, 0.5 to 1.0 percent of KI,1.0 to 5.0 percent of glycerin, 5.0 to 15.0 percent of phosphate buffer and the margin is water. The preparation method of the stable type povidone iodine disinfectant comprises the steps as follows: a. the PVP-I and the KIO3 are dissolved in purified water; b. NaOH aqueous solution is used for adjusting pH to 6.0; c. the glycerin and the phosphate buffer are added into and stirred evenly; and d. the KI is added into and stirred evenly. The disinfectant can not only guarantee the stable iodine content of the povidone iodine disinfectant but also can guarantee the stable pH value of the iodine-containing disinfectant.

Description

technical field The invention relates to an iodine-containing disinfectant, in particular to a povidone-iodine disinfectant and a preparation method thereof. Background technique Povidone-iodine has now become an internationally recognized high-efficiency, broad-spectrum, non-toxic fungicide, which has extremely strong bactericidal power and a wide spectrum of fungicides. It has a strong killing effect on Staphylococcus aureus, Neisseria gonorrhoeae, Pseudomonas aeruginosa, Treponema pallidum, hepatitis B virus, HIV, Trichomonas vaginalis, spores, etc. In vitro tests on common clinical bacteria, There is almost no bacteria that cannot be killed. There are multiple iodine (type) bodies in povidone-iodine solution, and there is a complex equilibrium relationship among them. Available iodine refers to the part of iodine that can be reduced by Na2S2O3, which is a part of available iodine. Povidone iodine is complex iodine, its content is relatively stable compared to iodine pr...

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Problems solved by technology

At present, most of these products are newly prepared for temporary use in medical institutions, which is very inconvenient and the product quality cannot be guaranteed.

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