Application of Japanese climbing fern spore in preparing lead excretion medicines or health products

A technology of sea sand and health care products, which is applied in the directions of medical preparations, drug combinations, and pharmaceutical formulas containing active ingredients.

Inactive Publication Date: 2009-10-07
LIAONING UNIVERSITY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] However, whether Haijinsha or its extract has the effect of promoting the body's lead discharge has not been reported in the literature.

Method used

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  • Application of Japanese climbing fern spore in preparing lead excretion medicines or health products
  • Application of Japanese climbing fern spore in preparing lead excretion medicines or health products

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0013] 50 healthy Kunming mice, clean grade, half male and half female, body weight 20±2g, divided into 5 groups, namely blank control group, lead-exposed model group, 3 decoctions of high, medium and low seaweed whole grass Dosage group, 10 rats in each group. Lead acetate was dissolved in distilled water and injected intraperitoneally at 40 mg / kg to establish a lead-exposed animal model in mice.

[0014] The water decoction of Haijinsha whole grass is prepared by conventional water decoction method and concentrated. The different dosage groups of the water decoction include high-dose group (9g / kg), middle-dose group (6g / kg), low-dose group (3g / kg), Each group was given the drug by intragastric administration, and the other groups were given the same amount of normal saline, and the experiment continued for 6 weeks. After the administration, take 40ul of blood from the right femoral vein of the mouse, put it into a covered plastic centrifuge tube filled with 0.36ml of 1% nit...

Embodiment 2

[0020] 50 healthy Kunming mice, clean grade, half male and half female, body weight 20±2g, divided into 5 groups, namely blank control group, lead-exposed model group, 3 decoctions of high, medium and low seaweed whole grass Dosage group, 10 rats in each group. Lead acetate was dissolved in distilled water and injected intraperitoneally at 40 mg / kg to establish a lead-exposed animal model in mice.

[0021] According to the same weight ratio, take Haijinsha powder (made by pulverizing mature spores and whole plants in the same weight ratio) and chrysanthemum, and prepare Haijinsha chrysanthemum water decoction by conventional water decoction method, concentrate, and administer by intragastric administration in each drug group, different Dosage groups include high-dose group (9g / kg), middle-dose group (6g / kg), and low-dose group (3g / kg) by intragastric administration respectively, and all the other groups are given equivalent normal saline by oral administration. 6 weeks. Afte...

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Abstract

The invention discloses new application of Japanese climbing fern spore in preparing lead excretion medicines or health products. The Japanese climbing fern spore can be prepared into medicines or health products for people with high lead.

Description

technical field [0001] The raw material involved in the present invention is the traditional Chinese medicine Haijinsha, specifically, its use in the preparation of medicines and health care products that promote the role of lead excretion in the body. Background technique [0002] Lead is a non-essential element for the human body. It has a strong affinity for body tissues, and by affecting the essential elements of the human body, it disturbs the balance of the physiological combination and proportional relationship of the essential elements in the human body, thereby disturbing the enzyme system in the body and the biomacro. The physiological activity of the molecule will cause the enzyme system in the body to lose its normal physiological activity and other regulation functions that regulate the balance of body functions will be disordered, thereby affecting multiple systems of the human body. The ideal concentration of lead in the blood is zero. However, with the accel...

Claims

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Application Information

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IPC IPC(8): A61K36/11A61K36/28A61K36/284A61K36/537A61K36/539A61K36/815A61K36/884A61P39/02
Inventor 蔡天革
Owner LIAONING UNIVERSITY
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