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Multichannel micro-fluidic chip specially used for AIDS diagnosis and comprising quasi-one-dimensional sensitive electrodes

A microfluidic chip and sensitive electrode technology, applied in the field of testing, to achieve the effects of reducing costs, strengthening chemical contact, and strengthening flow impact

Inactive Publication Date: 2009-11-18
NINGBO UNIV
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  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] At present, in the field of microfluidic chip technology, the technology of simultaneous detection and rapid diagnosis of AIDS using multiple characteristic antibodies of AIDS has not been reported.

Method used

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  • Multichannel micro-fluidic chip specially used for AIDS diagnosis and comprising quasi-one-dimensional sensitive electrodes

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Embodiment Construction

[0019] exist figure 1 In the shown example of this case, the structure of the microfluidic chip includes two plates that are attached together, and the two plates are respectively the cover sheet of the microfluidic chip and the base of the microfluidic chip. sheet, a capillary channel is installed at the position where the two plates fit together, and three micro-reservoirs, the three micro-reservoirs are micro-reservoir 1, micro-reservoir 2 and a micro-reservoir 10, one end of the capillary channel communicates with the micro-reservoir 1 and the micro-reservoir 2 via the Y-shaped triple channel 3, and the other end of the capillary channel communicates with the remaining micro-reservoir 10, and , the working electrode, the counter electrode 8 and the reference electrode 9 respectively installed in different positions in the capillary channel in sequence, the working electrode is composed of a metal electrode and the surface layer of antibody material coated on the metal elec...

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Abstract

The invention relates to a multichannel micro-fluidic chip specially used for AIDS diagnosis and comprising quasi-one-dimensional sensitive electrodes, belonging to the field of test. One of the hopes in the progress of medical techniques is to quickly diagnose AIDS at low cost. The invention provides a micro-fluidic chip that uses a plurality of AIDS characteristic antibodies to simultaneously detect and quickly diagnose AIDS. The chip is provided with three micro liquid storage tanks. The key points of the proposal lie in that the inner of the chip contains capillary channels of parallel structure, the parallel structure contains four micro-channels mutually connected in parallel, four working electrodes of bead string structure in total are respectively arranged in the four micro-channels, the substances on the superficial coats of the four working electrodes of bead string structure are respectively four antibody substances, namely, AIDS antibodies p24, gp41, gp120 and gp36. The application of the chip is conducive to increasing the diagnosis efficiency of AIDS as shown by the structural characteristics.

Description

technical field [0001] The invention relates to a special multi-channel microfluidic chip for AIDS diagnosis including a quasi-one-dimensional sensitive electrode, which belongs to the testing field. Background technique [0002] AIDS (AIDS) is a chronic infectious disease caused by HIV, transmitted through sexual contact and body fluids, capable of destroying human cellular immune system, and characterized by opportunistic infections and malignant tumors. Strengthening the monitoring and early diagnosis of HIV-infected and AIDS patients to achieve the purpose of controlling the AIDS epidemic has become an important topic of concern to all medical workers, and it is also a tireless goal pursued by governments of all countries. Currently, the diagnosis of AIDS is mainly based on epidemiology, clinical symptoms and laboratory tests. Among them, HIV antibody detection is the most commonly used method in AIDS detection, and HIV antibody is also the most important indicator. AI...

Claims

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Application Information

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IPC IPC(8): G01N33/574G01N33/543G01N27/327G01N27/48
Inventor 干宁杨欣李天华王鲁雁王峰巫远招李榕生
Owner NINGBO UNIV
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