Application of Chinese medicinal composition in preparation of medicament for treating diabetic complication

A composition and diabetes technology, applied in the direction of drug combination, drug delivery, metabolic diseases, etc., can solve the problems of undisclosed traditional Chinese medicine composition application, etc., and achieve the effect of improving nerve conduction velocity, reducing glutathione, and increasing the amount

Active Publication Date: 2009-12-30
HEBEI YILING MEDICINE INST
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The above-mentioned patent does not disclose the application of the traditional Chinese medicine composition in the preparation of drugs for the treatment of diabetic complications

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0046] The raw material drug formula is:

[0047] Ginseng 102g, Polygonatum 136g, Atractylodes 68g, Ruoginseng 56g, Poria cocos 83g, Ophiopogon japonicus 136g, Polygonum multiflorum 83g, Rehmannia glutinosa 102g, Cornus officinalis 136g, Coptis 56g, Peilan 56g, Lychee seed 136g, Epimedium 56g, Anemarrhena 68g, Salvia miltiorrhiza 89g, Pueraria 136g, Digupi 83g.

[0048] The preparation method is:

[0049] a. Weigh Chinese medicinal materials according to the prescription amount, cleanly select and break;

[0050] b. Add 6 times the amount of water to Peilan and Cangzhu to extract the volatile oil. The oil extraction time is 5 hours. The volatile oil is collected in another device, and the aqueous solution is filtered for later use, and the residue is discarded;

[0051] c. Cornus officinalis is impregnated with 7 times the amount of 75% ethanol for 24 hours, then percolated, the percolated liquid is collected, the ethanol is recovered, and concentrated into a thick paste wit...

Embodiment 2

[0057] The raw material drug formula is:

[0058] Ginseng 42g, Polygonatum 200g, Atractylodes 30g, Sophora flavescens 60g, Poria cocos 35g, Ophiopogon japonicus 200g, Polygonum multiflorum 35g, Rehmannia glutinosa 120g, Cornus officinalis 50g, Coptis 60g, Peilan 30g, Lychee seed 150g, Epimedium 30g, Anemarrhena 100g, Salvia miltiorrhiza 35g, Pueraria 200g, Digupi 30g. The preparation method is:

[0059] a. Weigh Chinese herbal medicines according to the prescription amount, cleanly select and break them;

[0060] b. Add 5 times the amount of water to Peilan and Cangzhu to extract the volatile oil. The oil extraction time is 3 hours. The volatile oil is collected in another device, and the aqueous solution is filtered for later use, and the residue is discarded;

[0061] c. After impregnating Cornus officinalis with 5 times the amount of 50% ethanol for 12 hours, carry out percolation, collect the percolation liquid, recover ethanol, and concentrate it into a thick paste with...

Embodiment 3

[0067] The raw material drug formula is:

[0068] Ginseng 160g, Polygonatum 50g, Atractylodes 100g, Sophora flavescens 20g, Poria cocos 100g, Ophiopogon japonicus 50g, Polygonum multiflorum 100g, Rehmannia glutinosa 50g, Cornus officinalis 200g, Coptidis 20g, Perrin 60g, Lychee seed 75g, Epimedium 60g, Anemarrhena 30g, Salvia miltiorrhiza 120g, Pueraria 50g, Digupi 100g.

[0069] The preparation method is:

[0070] a. Weigh Chinese herbal medicines according to the prescription amount, cleanly select and break them;

[0071] b. Add 9 times the amount of water to Peilan and Cangzhu to extract the volatile oil. The oil extraction time is 6 hours. The volatile oil is collected in another device, and the aqueous solution is filtered for later use, and the residue is discarded;

[0072] c. Cornus officinalis is soaked with 9 times the amount of 90% ethanol for 48 hours, then percolated, the percolated liquid is collected, the ethanol is recovered, and concentrated into a thick pa...

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PUM

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Abstract

The invention discloses application of a Chinese medicinal composition in preparation of a medicament for treating diabetic complication. By improving the nerve conductive velocity, reducing the content of glucitol, increasing blood flow of nerves and increasing number of open blood vessels, the medicament possesses the obvious function of alleviating pathological changes of the kidney, eyes and nerves caused by diabetes.

Description

technical field [0001] The invention relates to a new application of a traditional Chinese medicine composition, in particular to the application of a traditional Chinese medicine composition in the preparation of medicines for treating diabetes and diabetic complications, and belongs to the field of traditional Chinese medicine applications. Background technique [0002] Diabetes is a metabolic disease with complex pathogenesis and difficult to control. When it develops to a certain extent, it will be complicated by various complications. The main risk of diabetes is the occurrence of diabetic chronic complications (DCC). These complications often involve the kidneys, heart, retina, nerves, etc., and are the main cause of death and disability due to diabetes. The treatment of diabetes is currently mainly manifested as blood sugar control and symptomatic treatment. There is still a lack of effective drugs to regulate diabetic complications, especially microvascular complica...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/898A61K9/48A61K9/20A61K9/10A61K9/16A61K9/14A61K9/02A61K9/12A61K9/08A61P3/10A61P25/00A61P9/14
Inventor 李向军安军永王超郑立发
Owner HEBEI YILING MEDICINE INST
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