Application of composite from trametes robinioplila murr, wolfberry and sealwort

A composition and application technology, applied in the field of plant extracts, can solve the problems of easy recurrence, large side effects, aggravation and deterioration, etc.

Inactive Publication Date: 2010-06-16
QIDONG GAITIANLI MEDICINES
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Most kidney diseases have a long course of disease, complex conditions, and are prone to recurrence or even aggravation. Long-term use of western medicine has serious side effects

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1-4

[0115] Preparation of extracts

[0116]

Example 1

Example 2

Example 3

Example 4

Huaier fungus (g)

150

250

300

600

Lycium barbarum (g)

100

150

200

400

Polygonatum (g)

75

120

150

300

[0117] (1) Take Huaier fungus, add water and decoct 3 times, add 7 times the amount of water for the first time, boil for 6 hours, filter, and use the extract for later use; add 5 times the amount of water for the second and third times, boil for 6 hours, filter , combined three extracts, concentrated under reduced pressure to obtain an extract with a relative density of 1.35-1.40 (55°C);

[0118] (2) Take another wolfberry fruit and Polygonatum plus 8 times of water, soak for half an hour, decoct twice, 45 minutes each time, combine the decoction, filter, and concentrate the filtrate to a dipping solution with a relative density of 1.35 or more (50-60°C). paste;

[0119] (3) The abov...

Embodiment 5-8

[0121] Preparation of Huaiqihuang Granules

[0122] Mix the combined extracts obtained in Examples 1-4, add appropriate amount of starch, powdered sugar and flavoring agent, granulate to make 1000g, and dry to obtain Huaiqihuang Granules I-IV.

[0123] The Huaiqihuang granules used in the following examples are the Huaiqihuang granules III obtained in Example 7.

Embodiment 9

[0125] Examples of Clinical Trials and Treatment of Acute Glomerulonephritis

[0126] Clinical Trials:

[0127] 130 patients with acute glomerulonephritis were randomly divided into a treatment group of 65 cases and a control group of 65 cases. The treatment group was treated with Huaiqihuang Granules, and the control group was treated with Sanjin Tablets (purchased from Guilin Sanjin Pharmaceutical Co., Ltd.), 14 days as a course of treatment.

[0128] Observation items: clinical symptoms, urine routine examination, renal function, etc.

[0129] Judgment criteria for curative effect: formulated with reference to the “Summary of the Symposium on the Diagnosis and Treatment of Kidney Diseases and Curative Effect Standards” of the Nephrology Professional Committee of the Chinese Association of Traditional and Western Medicine in 2003. Cured: Clinical symptoms and signs disappeared, renal function was normal, three consecutive urine routine examinations were normal; Effective: ...

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PUM

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Abstract

The invention discloses an application of a composite in preparing medicine for treating nephropathy. The composite contains water extractive of raw medicinal materials. The raw medicinal materials comprise trametes robinioplila murr, wolfberry and sealwort.

Description

technical field [0001] The present invention relates to plant extracts, in particular to the use of compositions derived from Huaier fungus, Lycium barbarum and Polygonatum. Background technique [0002] Huai Er (Huai Er) is a medicinal fungus with the scientific name Trametes robiniophila Murr. It only grows on the trunk of the old Chinese Sophora japonica tree. According to the classification system of Ainsworth et al. in 1973, it belongs to Basidiomycotina, Polyporaceae, Trametes. As used herein, Huaier fungus is an artificial culture of natural Huaier. Huai Er fungus is a medicinal fungus, bitter in taste, pungent in nature, and enters the heart and liver meridians. It has the effects of treating wind, breaking blood and benefiting strength. [0003] Lycium barbarum (Fructus Lycii): the fruit of Lycium barbarum L., a plant of the genus Lycium in the family Solanaceae. It has the functions of nourishing liver and kidney, benefiting energy and improving eyesight. [0...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8969A61K45/06A61P13/12
Inventor 徐无为陆正鑫
Owner QIDONG GAITIANLI MEDICINES
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