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Novel compound antihypertensive preparation

A compound preparation and high blood pressure technology, which is applied in the field of medicine, can solve problems such as inaccurate clinical dosage, influence on drug efficacy, and increased side effects, and achieve the effect of improving antihypertensive efficacy, less adverse reactions, and good antihypertensive effect

Inactive Publication Date: 2010-06-30
JIANGSU JIBEIER PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0026] The product of the present invention overcomes that when irbesartan and fosinopril are used clinically, the drug dosage is increased in order to ensure the curative effect when a single drug is used alone, resulting in a significant increase in side effects; Preparations, but the use of clinical dosage is not accurate, the defect that affects the efficacy of drugs

Method used

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  • Novel compound antihypertensive preparation
  • Novel compound antihypertensive preparation

Examples

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Embodiment 1

[0043] A compound preparation containing the following components:

[0044] Irbesartan 150mg

[0045] Fosinopril 20mg

[0046] Starch 20mg

[0047] Calcium Sulfate 8mg

[0048] Talc 2mg

[0049]This embodiment can be made into compound irbesartan-fosinopril tablet, and the preparation method can adopt the preparation method of common pharmaceutical preparations.

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Abstract

The invention discloses a novel compound antihypertensive preparation which comprises 50-200mg of irbesartan and 5-30mg of fosinopril. Aiming at solving the problem that currently when only one of irbesartan and fosinopril is used clinically, in order to ensure the curative effect, the dosage of the drug is increased, which leads to obvious increase of the side effects, the invention provides a novel compound preparation. Irbesartan and fosinopril are used together, so synergic and complementary curative effect can be produced. The novel compound antihypertensive preparation enhances the tolerance of the patient, improves the compliance and reduces the dosage and the adverse reaction, and is convenient to take and cheap in price.

Description

technical field [0001] The invention relates to the technical field of medicine and discloses a new compound antihypertensive preparation. Background technique [0002] Hypertension is the most common cardiovascular disease and a major public health problem worldwide. my country currently has about 100 million hypertensive patients. According to the epidemiological survey in 1991, the awareness rate of hypertension in my country's urban and rural areas was 36% and 13%, and the treatment rate was 17% and 5%, respectively. The form of hypertension prevention and treatment is quite severe. According to the forecast of WTO, by 2020, non-communicable diseases will account for 79% of the causes of death in my country, among which cardiovascular diseases will take the first place. [0003] Commonly used antihypertensive drugs include the angiotensin receptor antagonist irbesartan and the angiotensin converting enzyme inhibitor fosinopril. [0004] Irbesartan (Irbesartan), the ch...

Claims

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Application Information

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IPC IPC(8): A61K31/675A61K31/4184A61P9/12
Inventor 俞新君吴修艮陈进王正丁德平朱月华
Owner JIANGSU JIBEIER PHARMA
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