Black pepper extract, preparation method thereof and application in preparation of medicaments for preventing and treating cough
A technology of black pepper and medicine, which is applied in the field of black pepper extract and its preparation and in the preparation of cough medicine, which can solve the problems of large toxic and side effects
- Summary
- Abstract
- Description
- Claims
- Application Information
AI Technical Summary
Problems solved by technology
Method used
Image
Examples
Embodiment 1
[0027] Preparation of black pepper total alkaloids and black pepper total volatile oil with different piperine content
[0028] 1. Extraction of the total volatile oil of black pepper: take the dried medicinal material, add 10 times the amount of water, and steam distill for 5 hours to extract the volatile oil of black pepper. The extraction rate of volatile oil is 2%, and 9g of crude drug is equivalent to 0.18ml of volatile oil extract.
[0029] 2. Preparation of total black pepper alkaloids containing 10% piperine: take the dried medicinal materials, extract 2 times with 10 times the amount and 8 times the amount of 90% ethanol, each time for one hour, filter, combine the two filtrates, and Recover ethanol under reduced pressure, and dry to obtain the total alkaloids of black pepper containing 10% piperine (the total alkaloids of black pepper in the present invention is the alkaloid part, the same applies throughout).
[0030] 3. Preparation of total black pepper alkaloids ...
Embodiment 2
[0033] Example 2 Antitussive experiment of black pepper total alkaloids containing different contents of piperine
[0034] 1. Preparation of test sample solution:
[0035] The total alkaloids of black pepper containing 10% piperine for testing sample solution: Accurately weigh 10g of total alkaloids of black pepper containing 10% piperine, dissolve in 100ml of 0.4% CMC-Na solution, and mix evenly by ultrasonic to obtain The black pepper total alkaloids test solution containing 10% piperine;
[0036] Containing 50% piperine total alkaloids of black pepper for testing sample solution: Accurately weigh 2.7g of black pepper total alkaloids containing 50% piperine, dissolve in 100ml of 0.4% CMC-Na solution, and ultrasonically mix, namely Obtain the black pepper total alkaloids test solution containing 50% piperine;
[0037] Containing 70% piperine total alkaloids of black pepper for testing sample solution: Accurately weigh 1.9g of black pepper total alkaloids containing 70% pipe...
Embodiment 3
[0048] Example 3 Cough-relieving experiment of black pepper alkaloids, volatile oil and compositions thereof
[0049] 1. Preparation of test solution:
[0050] Positive drug test solution: Accurately measure 39ml of Jizhi syrup, dissolve it in 100ml of 0.4% CMC-Na solution, and mix it by ultrasonic to get the positive drug test solution;
[0051] The test solution for the volatile oil part: accurately measure 0.9ml of volatile oil, dissolve it in 100ml of 0.4% CMC-Na solution, and mix it by ultrasonic to get the test solution for the volatile oil part;
[0052] Alkaloid part test solution: Accurately weigh 1.9g of black pepper total alkaloids containing 70% piperine, dissolve in 100ml of 0.4% CMC-Na solution, and mix with ultrasonic to obtain the total alkaloid test solution;
[0053] The volume / weight ratio is the composition test solution of 5:1: Accurately measure 2.25ml of volatile oil, accurately weigh 0.95g of black pepper total alkaloids containing 70% piperine, and di...
PUM
Abstract
Description
Claims
Application Information
- R&D Engineer
- R&D Manager
- IP Professional
- Industry Leading Data Capabilities
- Powerful AI technology
- Patent DNA Extraction
Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.
© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com