33results about How to "Curative effect" patented technology

At present, when any myopia or amblyopia therapeutic apparatus which remedies two eyes synchronously by light is used for remedying, the affected eyes are all passive. Although the brightness of the relative lightening view points of two eyes from the apparatus are same, the feeling intensity towards the light of the affected eye is much lower than healthy eye, so the due curative effect of the original apparatus is influenced seriously. The present invention uses the method of adjusting the brightness of the relative lightening view points of left and right eyes respectively to increase the brightness of the relative lightening view points of the affected eye, and/or the brightness of the relative lightening view points of the healthy eye is reduced to reduce the light sensation intensity of the healthy eye, which ensures that the light sensation intensities of the left and the right eyes are in the balanced state, or the light sensation intensity of the affected eye is stronger than that of the healthy eye. Therefore, the method of the present invention can increase the chance and improve the capability of the affected eye of participating in exercise, participating vision and restoring the eyesight, which ensures the due curative effect of the original apparatus in the therapy theory.

The invention discloses a traditional Chinese medicine composition and a preparation method thereof, particularly a traditional Chinese medicine superfine powder for preventing and treating chicken colibacillosis and a preparation method thereof. The traditional Chinese medicine superfine powder for preventing and treating chicken colibacillosis is characterized by comprising radix astragali, Bighead Atractylodes Rhizome, radix sileris, anemone, coptis, phellodendron bark, Cortex Fraxini and licorice. The traditional Chinese medicine superfine powder is mainly used for treating diarrhoea caused by chicken colibacillus; and the traditional Chinese medicine superfine powder can enhance the immunological competence of chickens and promote the production performance of chickens, is sensitive to pathogenic colibacillus of drug-resistant chickens, has obviously curative effect on chicken colibacillosis, and is safe and reliable. The medicine is made of pure traditional Chinese medicine preparation, thereby having no toxic or side effect; and the traditional Chinese medicine superfine powder has the advantage of small dosage, saves the culture cost, enhances the palatability for chicken, and meets the development requirements of high efficiency, quick acting, long acting, small dosage, small side effect, small toxicity and convenient use for new veterinary medicines.

The present invention relates to a method for drug delivery via brain extracellular space (ECS). It includes putting head of patient in an imaging apparatus; generating dynamic images of the brain via the imaging apparatus; delivering drugs into brain ECS of the patient according to the dynamic images and the drugs get to the therapeutic target by simple diffusion along concentration gradient. The present invention also relates to a device for drug delivery via brain ECS. Basing on the self-diffusion delivery (SDD) of drugs in brain ECS, the present invention can deliver drug into the ECS of the brain's relatively safe area in low speed, with small amounts of doses and without extra stress. Therefore, the present invention can reduce delivery time and dose of drugs, relieve injection pressure, decrease damages on normal brain tissue, and reduce the cost of treatment observably.

The invention discloses a thrombolytic active polysaccharide mixture preparation technology. The technology is characterized by preparing a polysaccharide mixture through mixing the concentrated polysaccharide mixed liquor of dendrobium officinale, chrysanthemum and hawthorn which are extracted by adopting a composite enzymic method with the fermentation liquor of black fungus and tolypocladium sinensis mycelia. The thrombolytic active polysaccharide mixture prepared by the technology has multiple biological activities, is a Chinese herbal medicinal microbial polysaccharide mixture with good quality and no toxic and side effect in the current world, can effectively treat cerebral thrombosis acute phase diseases, and has obvious treatment and prevention functions on acute phase sequela recovery and relapse prevention as well as a special effect on the efficacy of a Chinese herbal medicinal polysaccharide and microbial mycelia polysaccharide mixture with obvious vascular wall softening and nutrition functions.

The invention relates to a traditional Chinese medicinal composition for treating intestinal tract diseases, wherein the raw materials include red ginseng 131 weight parts, scented tea 2500 weight parts, bitter orange 250 weight parts. The invention also discloses the process for preparing the medicament.

The invention relates to composition containing alkaloid and essential oil which are extracted from black pepper, a preparation method thereof and application in the preparation of medicaments for treating cough, expectoration and upper respiratory tract inflammation which are caused by various reasons. The composition is superior to positive acute bronchitis syrup.

The invention discloses a preparation method and a quality detection method of coxtex moutan formula granules. The preparation method comprises the following steps: (1) decocting decoction pieces of coxtex moutan with water and conducting extracting so as to obtain an extracting solution; (2) conducting decompressing and concentrating in a filtrate concentrator so as to obtain an extractum; and (3) mixing the obtained extractum with such adjuvants as dextrin or lactose or maltodextrin and the like, uniformly stirring the materials, and conducting spray-drying, so that the coxtex moutan formula granules are obtained. A fingerprinting determination method of the coxtex moutan formula granules comprises the following steps: (1) preparing a reference solution; (2) precisely adding ethanol to powder of the coxtex moutan formula granules and conducting ultrasonic treatment; and (3) injecting an obtained material into a high performance liquid chromatograph, and recording a chromatogram map. The preparation method provided by the invention has the beneficial effects that the produced formula granules are uniform, stable and controllable in quality, and the formula granules have the advantages of being decoction-free and instant, convenient to carry and the like. The adopted fingerprinting detection method is convenient, rapid, and excellent in high precision, repeatability and stability; therefore, a novel method is provided for enhancing quality control of the coxtex moutan formula granules.

The invention provides a composition for treating a coronary heart disease and angina pectoris. The composition is mainly prepared from the crude drugs in different parts by weight: radix salviae miltiorrhizae, radix notoginseng, rhizoma corydalis, ginseng, rhizoma chuanxiong and the like. The composition has a better treatment effect on the coronary heart disease and angina pectoris.

The invention discloses a traditional Chinese medicine preparation for treating ear diseases of dogs and cats and a preparation method thereof and aims to solve the technical problem that existing medicine is inconvenient to use and poor in effect. The traditional Chinese medicine preparation is composed of cortex phellodendri, radix sophorae flavescentis, radix stemonae, cortex dictamni, paederiafoetida, houttuynia cordata, mint and borneol and is pasty missible oil obtained by heating and decocting. Traditional Chinese medicine is reasonably combined, and components are synergistic, so thatthe preparation has remarkable effect on preventing and treating pet body surface bacterial and fungal infection and is mainly used for treating diseases like pruritus, erythema and hair loss of dogsand cats caused by infection of microorganisms like bacteria and fungi and acarid in ear canals. The traditional Chinese medicine preparation is simple in preparation method, convenient to use and suitable for large-scale industrial production.

Disclosed is a medicament for treating chronic renal failure, which belongs to the technical field of a traditional Chinese medicine preparation. The medicament mainly comprises sixteen kinds of raw herbs of American ginseng, radix astragali, aconitum carmichaeli, poria cocos, smilax glabra, cornus officinalis, motherwort, oriental waterplantain rhizome, rheum officinale, and the like. The raw herbs are prepared by pharmaceutical equipment into qualified products with various kinds of dosage forms such as capsules, tablets and oral liquid for usage. The medicament in the invention has the efficacy of tonifying qi and replenishing the kidney, activating blood and resolving stasis, warming yang and fortifying the spleen, and resolving the turbid and draining water, and has better therapeutic effect on treating chronic renal failure. Time and frequency of hemodialysis of patients can be decreased and financial burden can be reduced.

The invention provides a recombinant adenovirus vector which contains a human transferrin receptor gene and a firefly luciferase gene and can simultaneously express a transferrin receptor protein and a luciferase protein in a eukaryotic cell. The construction method of a double-reporter-gene recombinant adenovirus vector is characterized by comprising the following steps in sequence: step (1), using a polymerase chain reaction (PCR) method to amplify the human transferrin receptor gene; step (2), inserting the human transferrin receptor gene segment amplified in step (1) in a shuttle vector containing a firefly luciferase gene segment to obtain a recombinant shuttle vector, and conducting sequencing analysis; step (3), connecting the recombinant shuttle vector which is verified correctly on a framework vector to obtain a recombinant adenovirus plasmid; step (4), conducting XhoI enzyme digestion determination on the recombinant adenovirus plasmid; and step (5), using a human embryo kidney cell, namly an HEK 203 cell, to pack the recombinant adenovirus plasmid to obtain the recombinant adenovirus vector. As indicated in an experiment, the recombinant adenovirus vector can be applied to magnetic resonance and optics bimodal imaging and used as a tumor tracer agent.

The invention discloses an anti-diabetic vinegar soaking bean drug and a preparation method thereof. The vinegar soaking bean drug comprises the following components: 2000 g of 9 degree rice vinegar, 300 g of soybeans, 300 g of black beans, 300 g of peanuts and 1 g of astaxanthin, or 300 g of soybeans, 300 g of black beans, 300 g of peanuts, 20 mg of astaxanthin and 1000 g of 9 degree rice vinegar. The preparation method of the vinegar soaking bean comprises the following steps: mixing 300 g of soybeans, 300 g of black beans and 300 g of peanuts, cleaning and airing; adding 2000 g of 9 degree rice vinegar to soak for 15 days; adding 1 g of astaxanthin to mix and stir uniformly; packaging, sealing and packing. According to the invention, peanuts, black beans and soybeans contain abundant astaxanthin, and generate the abundant astaxanthin after being soaked in 9 degree rice vinegar; during the preparation process, natural astaxanthin is manually added; astaxanthin is an ultra-strong anti-oxidant, has excellent curative effects on anti-tumor, anti-hypertension and anti-diabetic, and has the curative effect of anti-hypertension when a patient eats 20 grains in an empty stomach in everyday morning; the vinegar soaking bean drug is cheap in formula price, and is a practical healing formula very suitable for masses.

The invention discloses a veterinary drug for treating diseases caused by bacteria and mycoplasma infection. The veterinary drug comprises erythromycin thiocyanate and trimethoprim. The veterinary drug has obvious curative effect on the diseases of the livestock and poultry caused by the bacteria and mycoplasma infection and can obviously shorten the course of the diseases. And meanwhile, the drug can be used conveniently and is worthy of being spread widely.

The invention discloses the application of a traditional Chinese medicine composition in the preparation of a medicine for treating secondary dysmenorrhea; the traditional Chinese medicine composition is 30g of angelica, 30g of motherwort, 15g of fried puhuang, 10g of Chuanxiong, 15g of Wulingzhi and 10g of red peony , Guizhi 10g, Atractylodes macrocephala 10g, Poria cocos 10g, peach kernel 10g, safflower 10g, adding water each time is 8 times and 6 times the volume of the total weight of the medicinal materials, decocted twice, combined the filtrate, and concentrated under reduced pressure liquid. The present invention is formed on the basis of traditional Chinese medicine theory of syndrome differentiation and treatment combined with many years of clinical experience. The inventor added peach kernels and safflower on the basis of using the first three doses of analgesic prescriptions to treat primary dysmenorrhea for the treatment of endometriosis It has obvious curative effect on secondary dysmenorrhea caused by endometriosis, adenomyosis, pelvic inflammatory disease, etc., especially for secondary dysmenorrhea caused by endometriosis, the curative effect reaches 96.4%.

The invention provides an etelcalcetide hydrochloride stabilizer, belonging to to the technical field of pharmaceutical peptides. The etelcalcetide hydrochloride stabilizer comprises modified polyethylene glycol-modified sulphaguanidine, wherein polyethylene glycol and isatoic anhydride are subjected to a carboxylation reaction to obtain modified polyethylene glycol, and the modified polyethylene glycol and sulphaguanidine are subjected to a condensation reaction to obtain the modified polyethylene glycol-modified sulphaguanidine. The modified polyethylene glycol-modified sulphaguanidine can prevent caking or denaturation failure of the etelcalcetide hydrochloride in a drying process of preparing freeze-dried etelcalcetide hydrochloride powder, and enables the etelcalcetide hydrochloride to stably exist under strong light irradiation.

The invention discloses a traditional Chinese medicine composition for treating hypertension and a preparing method thereof. The traditional Chinese medicine composition is prepared from raw radix astragalis, cortex eucommiae, rhizoma alismatis, rhizoma atractylodis, the rhizome of chuanxiong, rhizoma gastrodiae, radix ophiopogonis, herba taxilli, prunella spike, herba siegesbeckiae, radix achyranthis bidentatae, sagina maxima and marigold. The preparing method comprises the steps of washing the raw materials and then conducting drying; smashing the dried raw materials respectively, and evenly mixing and stirring the smashed raw materials to obtain mixed powder; decocting the mixed powder with water to obtain decoction liquid, filtering the decoction liquid to obtain decoction dregs and liquid medicine, and concentrating the liquid medicine and conducting drying to obtain the traditional Chinese medicine composition for treating hypertension. The traditional Chinese medicine composition for treating hypertension has the advantages that the raw materials are organically combined to reduce blood pressure, and hypertension symptoms including yin and blood deficiency, headache and dizziness, neuralgia, weakness and limbs anesthesia can be well treated.

The invention discloses a Miao medicament for treating emphysema and a preparation method thereof. The Miao medicament is prepared from the following drug materials in parts by mass: 15-20 parts of rapeseed, 10-15 parts of perilla leaf, 10-15 parts of flos farfarae, 5-10 parts of inula flower, 15-20 parts of platycodon grandiflorum, 20-25 parts of loquat leaf, 10-15 parts of bighead atractylodes rhizome, 5-10 parts of semen brassicae, 5-10 parts of liqourice, 10-15 parts of white peony, 10-15 parts of poria and 10-15 parts of bulbus fritillariae cirrhosae. The preparation method comprises the following steps: washing, baking, crushing and disinfecting the 12 medicinal materials; mixing according to the proportion, immersing in a pottery container or copper tank or wooden drum or pool built by cement with water, introducing steam for heating or continuously decocting and extracting until effective components are basically extracted; making extract by filtered liquid medicaments; baking, crushing and grinding; and tableting or filling into capsules according to a conventional pharmaceutical preparation process. The Miao medicament is convenient to process and remarkable in curative effect, and is suitable for treating patients with emphysema.