Production method of pine pollen tablets for treating premature ovarian failure of women
A technology for premature ovarian failure and production method, which is applied in the directions of medical raw materials, sexual diseases, and pill delivery derived from gymnosperm subphylum, can solve the problems of reduced product activity titer, uneven quality, and scarcity of export products, and achieves retention. The effect of functional substance activity, accurate sub-packaging dose, and non-oxidative deterioration
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[0018] 1. Prepare the freeze-dried powder of pollen aqueous extract for the treatment of premature ovarian failure in women:
[0019] 1. Sorting pollen: remove impurities in pine pollen at room temperature.
[0020] 2. Breaking the wall: the pollen that has been removed is broken under the frequency of the grading motor at a frequency of 55-60 Hz and the air source pressure of 0.7-1.0 MPa.
[0021] 3. Soaking and ultrasonic treatment: Soak the pollen after the wall-breaking treatment in water at normal pressure and temperature, and treat it with ultrasonic waves for 20 to 40 minutes.
[0022] 4. Impurity removal: Centrifuge the ultrasonically treated material in a refrigerated centrifuge at 8000-12000 rpm for 10-15 minutes to remove solid impurities and take the supernatant.
[0023] 5. Ultrafiltration: pass the supernatant through a molecular sieve below 5000D at an ambient temperature of 1-5°C, and separate the water-soluble matter with a molecular weight less than 5000D, w...
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