Chinese medicinal compound preparation for treating rheumatoid arthritis and preparation method thereof

Abstract

The invention relates to a compound Chinese medicinal preparation for treating rheumatoid arthritis, which comprises the following Chinese medicinal raw materials by weight: 14 to 16 grams of white paeony root, 14 to 16 grams of rhizoma anemarrhenae, 14 to 16 grams of cassia twig, 19 to 21 grams of astragalus, 9 to 11 grams of Chinese angelica, 9 to 11 grams of incised notopterygium rhizome , 9 to 11 grams of pubescent angelica root, 9 to 11 grams of clematis root and 4 to 6 grams of tripterygium. A preparation method for the compound Chinese medicinal preparation comprises the following steps of: cleaning the nine medicinal materials, mixing according to a ratio, adding water in an amount which is 5 to 7 times that of the total weight of the medicinal materials or 70 volume percent of ethanol, decocting twice, namely decocting for 1 hour every time, merging decoction at two times, filtering, and concentrating to obtain fluid extract with the specific gravity of 1.15 at 60 DEG C. The Chinese medicinal preparation can be prepared into pharmaceutically-acceptable formulations such as tablets, capsules, granules, dripping pills, oral liquid, pills, syrup, dispersible tablets and effervescent tablets by the conventional preparation process. Compared with tripterygium glycoside tablets, the compound Chinese medicinal preparation has good curative effect and small side effect.

Description

technical field [0001] The invention relates to a compound traditional Chinese medicine preparation for treating rheumatoid arthritis and a preparation method thereof, belonging to the field of traditional Chinese medicine preparations. Background technique [0002] Rheumatic diseases are a class of diseases with high clinical morbidity and great harm. Many rheumatic diseases are clinically difficult and severe, some diseases have a high disability rate, and some diseases are dangerous and life-threatening. And it can occur in people of all age groups, and the incidence rate increases with age. At present, the incidence of rheumatic diseases in mainland China is increasing year by year. Among them, the most serious rheumatoid arthritis has more than 4.4 million patients, and the number of ankylosing spondylitis patients has reached 3.9 million. If not timely and effective treatment, many patients will result in disability, loss of work and living ability. As the disease p...

AI Technical Summary

Problems solved by technology

[0003] In the past, there was a lack of effective diagnosis and treatment methods for this type of disease, and because most of them have a chronic course, people generally do not know enough about this type of disease, and often use some painkillers or glucocorticoids and other chemical drugs, which may temporarily relieve pain at first, but over time. Gradually deformed joints lead to disability, and even damage to internal organs, which can be life-threatening in severe cases

[0004] Currently, Tripterygium wilfordii is the most commonly used traditional Chinese medicine in the treatment of rheumatoid arthritis in my country, but its serious side effects on the heart, liver, kidney, hematopoietic system, gastrointestinal tract, and reproductive system make it difficult for many patients to persist

The traditional Chinese medicine raw materials of Radix Paeoniae Alba, Zhimu, Guizhi, Astragalus, Angelica, Duhuo, Notopterygium provided by the present invention have been used alone or in combination with other traditional Chinese medicines to treat rheumatoid arthritis, but the above-mentioned seven traditional Chinese medicines are used in combination to treat rheumatoid arthritis. The effect is more obvious, and its weight ratio and deletion have a significant impact on the curative effect of treating rheumatoid arthritis

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