Chinese medicinal compound preparation for treating rheumatoid arthritis and preparation method thereof

An arthritic and rheumatoid technology, applied in the field of traditional Chinese medicine preparations, can solve problems such as life-threatening, difficult to adhere to, and damage to internal organs

Inactive Publication Date: 2011-09-14
INST OF BASIC RES & CLINICAL MEDICINE CHINA ACAD OF CHINESE MEDICAL SCI
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] In the past, there was a lack of effective diagnosis and treatment methods for this type of disease, and because most of them have a chronic course, people generally do not know enough about this type of disease, and often use some painkillers or glucocorticoids and other chemical drugs, which may temporarily relieve pain at first, but over time. Gradually deformed joints lead to disability, and even damage to internal organs, which can be life-threatening in severe cases
[0004] Currently, Tripterygium wilfordii is the most commonly used traditional Chinese medicine in the treatment of rheumatoid arthritis in my country, but its serious side effects on ...

Method used

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  • Chinese medicinal compound preparation for treating rheumatoid arthritis and preparation method thereof
  • Chinese medicinal compound preparation for treating rheumatoid arthritis and preparation method thereof
  • Chinese medicinal compound preparation for treating rheumatoid arthritis and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0010] Embodiment 1: a kind of Chinese medicine compound preparation for the treatment of rheumatoid arthritis, its prescription is: Radix Paeoniae Alba 15g, Anemarrhena 15g, Guizhi 15g, Astragalus 20g, Angelica 10g, Duhuo 10g, Notopterygium 10g, Clematis 10g, Tripterygium wilfordii 5g.

[0011] The preparation method is to wash the 9 medicinal materials, mix them in proportion, add 6 times the total weight of the medicinal materials and decoct them twice, each time for 1 hour, combine the decoctions for 2 times, filter, and concentrate to obtain Proportion is the liquid extract of 1.15, adopts conventional preparation process, and Chinese medicine preparation of the present invention can be made into any said dosage form in pharmacy, as: tablet, capsule, granule, drop pill, oral liquid, pill, Syrup, dispersible tablet, effervescent tablet.

Embodiment 2

[0012] Embodiment 2: A kind of traditional Chinese medicine compound preparation for the treatment of rheumatoid arthritis, its prescription is: Radix Paeoniae Alba 16g, Anemarrhena 16g, Guizhi 16g, Astragalus 21g, Angelica 11g, Duhuo 11g, Notopterygium 11g, Clematis 11g, Tripterygium wilfordii 6g.

[0013] The preparation method is to wash the 9 medicinal materials, mix them in proportion, add water 7 times the total weight of the medicinal materials and decoct twice, and the rest of the preparation method is as in Example 1.

Embodiment 3

[0014] Embodiment 3: a kind of traditional Chinese medicine compound preparation for the treatment of rheumatoid arthritis, its prescription is: Radix Paeoniae Alba 14g, Anemarrhena 14g, Guizhi 14g, Astragalus 19g, Angelica 9g, Duhuo 9g, Notopterygium 9g, Clematis 9 grams, Tripterygium wilfordii 4g.

[0015] The preparation method is to wash the 9 medicinal materials, mix them in proportion, add 5 times the total weight of the medicinal materials and decoct twice, and the rest of the preparation methods are as in Example 1.

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Abstract

The invention relates to a compound Chinese medicinal preparation for treating rheumatoid arthritis, which comprises the following Chinese medicinal raw materials by weight: 14 to 16 grams of white paeony root, 14 to 16 grams of rhizoma anemarrhenae, 14 to 16 grams of cassia twig, 19 to 21 grams of astragalus, 9 to 11 grams of Chinese angelica, 9 to 11 grams of incised notopterygium rhizome , 9 to 11 grams of pubescent angelica root, 9 to 11 grams of clematis root and 4 to 6 grams of tripterygium. A preparation method for the compound Chinese medicinal preparation comprises the following steps of: cleaning the nine medicinal materials, mixing according to a ratio, adding water in an amount which is 5 to 7 times that of the total weight of the medicinal materials or 70 volume percent of ethanol, decocting twice, namely decocting for 1 hour every time, merging decoction at two times, filtering, and concentrating to obtain fluid extract with the specific gravity of 1.15 at 60 DEG C. The Chinese medicinal preparation can be prepared into pharmaceutically-acceptable formulations such as tablets, capsules, granules, dripping pills, oral liquid, pills, syrup, dispersible tablets and effervescent tablets by the conventional preparation process. Compared with tripterygium glycoside tablets, the compound Chinese medicinal preparation has good curative effect and small side effect.

Description

technical field [0001] The invention relates to a compound traditional Chinese medicine preparation for treating rheumatoid arthritis and a preparation method thereof, belonging to the field of traditional Chinese medicine preparations. Background technique [0002] Rheumatic diseases are a class of diseases with high clinical morbidity and great harm. Many rheumatic diseases are clinically difficult and severe, some diseases have a high disability rate, and some diseases are dangerous and life-threatening. And it can occur in people of all age groups, and the incidence rate increases with age. At present, the incidence of rheumatic diseases in mainland China is increasing year by year. Among them, the most serious rheumatoid arthritis has more than 4.4 million patients, and the number of ankylosing spondylitis patients has reached 3.9 million. If not timely and effective treatment, many patients will result in disability, loss of work and living ability. As the disease p...

Claims

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Application Information

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IPC IPC(8): A61K36/8964A61P19/02A61P29/00
Inventor 吕爱平吕诚姜淼何小娟张驰
Owner INST OF BASIC RES & CLINICAL MEDICINE CHINA ACAD OF CHINESE MEDICAL SCI
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