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Extracorporeal circulation cancer cell purification system

A technology of extracorporeal circulation and purification system, which is applied in the direction of blood circulation treatment, etc.

Inactive Publication Date: 2011-11-30
俞能旺
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The above-mentioned structure is an extended application of extracorporeal circulation, and a specific component of extracorporeal circulation column is added accordingly, and its application has certain limitations

Method used

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  • Extracorporeal circulation cancer cell purification system
  • Extracorporeal circulation cancer cell purification system
  • Extracorporeal circulation cancer cell purification system

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Embodiment Construction

[0023] Refer to the attached figure 1 , which shows an extracorporeal circulation cancer cell purification system, its basic structure is that it includes probes for providing cobalt ferrite-coupled tumor-specific antibodies arranged on the channel of the extracorporeal circulation based on the connecting pipeline A probe pump 3, a blood pump 5 providing circulation power, and a magnetic separator 8 with a magnetic separation column 12 inside, wherein the magnetic separator is located at the rear stage of the probe pump.

[0024] With regard to the decontamination system, a drainage device such as a puncture catheter can be integrated, or it can be configured separately.

[0025] Based on the above structure, the blood of cancer patients is pumped out of the body, and the CTC cells are purified by a purification system before being reinfused into the body. After a certain number of cycles, the CTCs in the blood can achieve the therapeutic effect of purification, and only 0.1% ...

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Abstract

The invention discloses an extracorporeal circulation cancer cell purification system, which includes a probe pump for providing probes for cobalt ferrite-coupled tumor-specific antibodies, which are set on the channel of the extracorporeal circulation based on connecting pipelines, A blood pump providing circulation power and a magnetic separator with a built-in magnetic separation column, wherein the magnetic separator is located at the rear stage of the probe pump. The invention can flexibly capture CTCs in or in vivo and purify the blood, thus providing a brand-new approach for reducing the occurrence of malignant tumor metastasis.

Description

technical field [0001] The invention relates to a cancer cell purification system based on extracorporeal circulation. Background technique [0002] Cancer metastasis is the most essential manifestation of malignant tumors, and it is also the main reason for the death of patients caused by tumors. 90% of solid cancer patients eventually die due to metastasis, so current cancer treatment strategies often focus on one point, that is, to prevent and block cancer metastasis. [0003] A large amount of evidence shows that in the early stage of solid cancer, cancer cells shed into the circulatory system, and these shed cancer cells are called circulating tumor cells (circulating tumor cells, CTC). Some CTCs can escape the circulatory system’s clearance mechanism for foreign bodies such as immune surveillance, and clone and proliferate in specific organs, leading to tumor recurrence and metastasis. CTCs are the precursors of many tumors to form metastases. [0004] In certain set...

Claims

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Application Information

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IPC IPC(8): A61M1/36
Inventor 俞能旺孟建中张爱民刘洁
Owner 俞能旺
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