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Oil in water (O/W) emulsion for treating skin trauma and preparation method of oil in water emulsion

A skin wound, oil-in-water technology, used in the field of scalds and gunshot wounds, and the treatment of burns, can solve problems such as the treatment, repair, regeneration and healing of unfavorable skin wound tissue cells, ineffective sterilization, anti-inflammatory, pain relief, and anti-seepage.

Active Publication Date: 2012-02-08
龚森淼
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0002] Skin trauma, especially burns, scalds and gunshot wounds, the epidermal layer of the skin and even deeper tissues are severely traumatized, general dry treatment is not conducive to the treatment, repair, regeneration and healing of skin wound tissue cells, general wet treatment The drugs cannot effectively sterilize, reduce inflammation, relieve pain, prevent seepage, and cannot repair, regenerate and heal traumatized cells and tissues as soon as possible.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0020] The various ingredients and their percentages by weight will be described below, taking the whole emulsion as 1000 ml.

[0021] The water phase substance of the present invention is distilled water, and the percentage by weight is 70% by weight-80% by weight;

[0022] Sodium chloride 10 grams;

[0023] 0.1-2 grams of lidocaine hydrochloride or lidocaine carbonate;

[0024] The nano-silver oxide particle of the present invention has a particle size of 10 to 200nm (nano), and due to its large specific surface area, the sterilization effect can be achieved in a small amount, and its weight is 0.001% by weight-0.01% by weight, and polar substances are used As a dispersant for nano-silver oxide particles, such as diphosphate, the dosage is very small, 0.0005%-0.01% by weight;

[0025] The fatty phase substance of the present invention accounts for 5-30% by weight, glycerin and vitamin E oil, wherein the vitamin E oil is 0.01% by weight;

[0026] The epidermal cell repair ...

Embodiment 2

[0035] The various ingredients and their percentages by weight will be described below, taking the whole emulsion as 1000 ml.

[0036] The water phase substance of the present invention is distilled water, and the percentage by weight is 70% by weight-80% by weight;

[0037] Sodium chloride 10 grams;

[0038] 0.1-2 grams of lidocaine hydrochloride or lidocaine carbonate;

[0039] The nano-silver oxide particle of the present invention has a particle size of 10 to 200nm (nano), and due to its large specific surface area, the sterilization effect can be achieved in a small amount, and its weight is 0.001% by weight-0.01% by weight, and polar substances are used As a dispersant for nano-silver oxide particles, such as diphosphate, the dosage is very small, 0.0005%-0.01% by weight;

[0040] The fatty phase substance of the present invention accounts for 5-30% by weight, glycerin and vitamin E oil, wherein the vitamin E oil is 0.01% by weight;

[0041] The epidermal cell repair ...

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Abstract

The invention relates to an oil in water (O / W) emulsion for treating skin trauma and preparation method of the oil in water emulsion, more particularly, the emulsion in the invention is also suitable for treating burn, scald and gunshot wounds. The O / W emulsion comprises a water phase material, a fat phase material, a widely-sterilized nano silver oxide particle, an epidermis cell repairing material, a moisture-remaining and crease-resisting material, a PH buffering agent, a penetrant, an antioxidant and fibronectin.

Description

technical field [0001] The invention relates to an oil-in-water O / W emulsion for treating skin wounds and a manufacturing method thereof. More specifically, the emulsion involved in the invention is also suitable for treating burns, scalds and gunshot wounds. Background technique [0002] Skin trauma, especially burns, scalds and gunshot wounds, the epidermal layer of the skin and even deeper tissues are severely traumatized, general dry treatment is not conducive to the treatment, repair, regeneration and healing of skin wound tissue cells, general wet treatment The traditional drugs cannot effectively sterilize, reduce inflammation, relieve pain, prevent seepage, and cannot repair, regenerate and heal traumatized tissues as soon as possible. [0003] There are a large number of bacteria multiplying in the wound, and there are also a large number of free radicals produced by stress, especially superoxide anion free radicals. The existence of free radicals will not be conduc...

Claims

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Application Information

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IPC IPC(8): A61K38/44A61K9/107A61P17/02A61K31/167A61K38/06A61K33/38A61K31/728A61K31/375A61K31/05A61K31/015A61K38/39
Inventor 龚森淼蒋天庆
Owner 龚森淼
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