Drug for curing periodontitis

A technology of periodontitis and medicine, which is applied in the field of periodontitis medicine, can solve the problems of inconvenient administration, impermeability of periodontitis, poor curative effect, etc., and achieve remarkable therapeutic effect, good fluidity and definite curative effect Effect

Inactive Publication Date: 2012-06-13
哈药集团中药二厂
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] The present invention aims to solve the problems that the existing drugs for treating periodontitis cannot penetrate into the deep part of the periodontal pocket, have poor curative effect and inconvenient administration, and provide a drug for treating periodontitis

Method used

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  • Drug for curing periodontitis
  • Drug for curing periodontitis
  • Drug for curing periodontitis

Examples

Experimental program
Comparison scheme
Effect test

specific Embodiment approach 1

[0009] Embodiment 1: The medicine for treating periodontitis in this embodiment is made of 5-250 parts by weight of doxycycline, 25-1000 parts of metronidazole and 10000 parts of glycerin.

[0010] The preparation method of the medicine for treating periodontitis in this embodiment is as follows: weigh 5 to 250 parts of doxycycline, 25 to 1000 parts of metronidazole and 10000 parts of glycerin in parts by weight, and mix doxycycline, Metronidazole and glycerin are mixed to obtain a suspension, which is the medicine for treating periodontitis. When using, inject the medicine for treating periodontitis with a flat needle into the periodontal pocket, and use it before going to bed, once a day.

[0011] In this embodiment, two kinds of antibiotics are used, both of which are broad-spectrum antibiotics, and the mutual cooperation can basically cover all bacteria in the oral cavity, so the curative effect is definite. The medicine for treating periodontitis of the invention has goo...

specific Embodiment approach 2

[0012] Embodiment 2: The medicine for treating periodontitis in this embodiment is made of 10-220 parts by weight of doxycycline, 50-950 parts of metronidazole and 10,000 parts of glycerin.

specific Embodiment approach 3

[0013] Embodiment 3: The medicine for treating periodontitis in this embodiment is made of 30-200 parts by weight of doxycycline, 100-900 parts of metronidazole and 10000 parts of glycerin.

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Abstract

The invention relates to a drug for curing periodontitis, which is used for solving the problems of being incapable of permeating in a deep part of a periodontal pocket, poor in curative effect and inconvenient for drug delivery in the traditional drug for curing periodontitis. The drug for curing periodontitis comprises the following components in parts by weight: 5-250 parts of doxycycline, 25-1000 parts of metronidazole, and 10000 parts of glycerol. According to the invention, two kinds of antibiotics which are broad-spectra antibiotics are adopted; the two antibiotics are matched with each other so as to basically cover all bacteria in an oral cavity, so that the curative effect is definite; due to the good viscosity, the drug for curing periodontitis disclosed by the invention can stay in the periodontal pocket for a long time; due to the good flowability, the drug for curing periodontitis can be injected into the periodontal pocket by using a fine needle, so that patients cannot feel pain; the patients can apply the drug, so that the drug of the patients can be delivered everyday can be ensured; and the drug concentration in the periodontal pocket can be effectively kept, thus, an obvious curative effect can be achieved.

Description

technical field [0001] The invention relates to a medicine for treating periodontitis. Background technique [0002] The existing treatment methods for periodontal disease are mainly cleaning and antibiotic treatment, wherein antibiotic treatment includes systemic administration (oral and injection) and periodontal local administration. main way. [0003] Existing drugs of this type mainly include some mouthwashes and gel-like periodontal pocket drug delivery sustained-release preparations, among which mouthwash drugs cannot penetrate into the deep part of the periodontal pocket, and the curative effect is poor. The curative effect of gel sustained-release drugs is definite in theory, but in practical application, subject to oral conditions, the curative effect is not ideal, mainly because the oral cavity is always active (especially when eating), and the given drugs cannot be absorbed in the oral cavity. Peripheral bags are retained, so the slow-release effect cannot be a...

Claims

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Application Information

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IPC IPC(8): A61K9/10A61K31/65A61K47/10A61P1/02A61P31/04A61K31/4164
Inventor 解黎雯李长新李文春付饶崔仁海李殿明王英新
Owner 哈药集团中药二厂
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