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Application of shortscape fleabane herb extract in preparation of medicine with anti-oxidation function

A technology of anti-oxidation and breviscapine, which is applied in the direction of drug combination, anti-toxic agent, pharmaceutical formula, etc., to achieve the effect of strong activity

Active Publication Date: 2012-06-13
YUNNAN SHIPURUI BIOLOGICAL ENG
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

) However, the current research on the antioxidant effect of Erigeron breviscapus mainly focuses on the research on the antioxidant activity of the medicinal material itself or its flavonoids, especially scutellarin, and less on other components in Erigeron breviscapus

Method used

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  • Application of shortscape fleabane herb extract in preparation of medicine with anti-oxidation function

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0021] Erigeron scutellaria extract, which contains a composition consisting of scutellaria, 3,5-dicaffeoylquinic acid, 4,5-dicaffeoylquinic acid and 1,5-dicaffeoylquinic acid.

Embodiment 2

[0023] Erigeron breviscapus extract, which contains 99% by weight of caffeoyl substances and 1% of pyrone substances (pyromeconic acid) prepared in Example 1.

Embodiment 3

[0025] Erigeron breviscapus extract, which contains caffeoyls produced in Example 1, 1% pyrones (pyromeconic acid) and 38% flavonoids (breviscapine) B element).

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Abstract

The invention relates to a shortscape fleabane herb extract in preparation of a medicine with an anti-oxidation function. The extract contains components of, by weight: 61-99% of a caffeoyl substance, 1-20% of a pyrone substance and 0-38% of a flavonoid substance. The invention also provides a composition with an anti-oxidation composition. The composition is characterized in that the compositioncomprises the shortscape fleabane herb extract comprising 61-99% of the caffeoyl substance, 1-20% of the pyrone substance and 0-38% of the flavonoid substance by weight. According to the invention, in shortscape fleabane herb, besides scutellarin, the other components such as the pyrone compound (pyromeconic acid) and the caffeoyl compounds (erigoster B, 3,5-dicaffeoylquinic acid, 4,5-dicaffeoylquinic acid, and 1,5-dicaffeoylquinic acid) also have anti-oxidative activities, and the composition thereof also has anti-oxidative activity. The anti-oxidative activity of the composition is higher.

Description

technical field [0001] The invention relates to the application of an extract of Erigeron breviscapus in the preparation of medicines with antioxidative effect, which belongs to the technical field of pharmacy. Background technique [0002] Free radicals are intermediate metabolites of various biochemical reactions in human life activities. Active oxygen free radicals are produced by cells during normal metabolic processes, or by exposure to high-energy radiation, hyperbaric oxygen, drugs, cigarette smoke, and photochemical air pollution. [0003] Free radicals exist objectively. For human beings, free radicals are constantly being produced no matter in vivo or in vitro. The incidence of diseases related to free radicals is also on the rise. With the deepening of the research on free radicals, the method of eliminating free radicals and reducing the harm of free radicals to the human body has gradually been revealed. [0004] Studies have shown that the process of free ra...

Claims

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Application Information

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IPC IPC(8): A61K36/28A61P39/06
Inventor 龙祥孙汉董胡志祥张秋玲史晓晨
Owner YUNNAN SHIPURUI BIOLOGICAL ENG
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