Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Oral care liquid for preventing chemotherapy-induced oral mucositis

A technology for oral care solution and oral mucositis, which is applied in the field of traditional Chinese medicine and can solve problems such as low efficiency

Inactive Publication Date: 2012-10-03
威海市妇女儿童医院
View PDF3 Cites 9 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The disadvantage of this method is: the total effective rate is low, probably maintained at about 60%

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Oral care liquid for preventing chemotherapy-induced oral mucositis

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0021] Example 1, the weight ratio of raw materials: white horse bone 6g, Ligustrum lucidum 8g, fig leaf 8g, habitat 6g, Scrophulariaceae 6g, Radix Ophiopogon japonicus 8g, Adenophora 6g, Anemarrhena 8g, Sarcorrhizae 3g.

Embodiment 2

[0022] Example 2, the weight ratio of raw materials: white horse bone 10g, Ligustrum lucidum 15g, fig leaf 15g, habitat 10g, Scrophulariaceae 10g, Ophiopogon japonicus 15g, Adenophora 10g, Anemarrhena 15g, Sarcodon 6g.

Embodiment 3

[0023] Example 3, the weight ratio of raw materials: white horse bone 8g, Ligustrum lucidum 10g, fig leaf 10g, habitat 8g, Scrophulariaceae 8g, Ophiopogon japonicus 10g, Radix Adenophora 8g, Anemarrhena 10g, Sargassum 5g.

[0024] When in use, add water to decoct the traditional Chinese medicine Baimagu, Ligustrum lucidum, Ficus fig leaf, habitat, Scrophulariae radix, Ophiopogon japonicus, Radix Adenophora, Sargassum and Anemarrhena twice, and combine the filtrates.

[0025] The effective combination and coordination of the above drugs can effectively achieve the purpose of preventing oral mucositis caused by chemotherapy, and has less side effects. The above results are fully proved by the clinical data, and the relevant data are as follows, wherein the drug used in the study is the weight ratio of the bulk drug in Example 3.

[0026] 1 Objects and methods.

[0027] 1.1 Subjects From May 2005 to December 2006, a total of 260 patients received chemotherapy with fluorouracil-b...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention discloses an oral care liquid for preventing chemotherapy-induced oral mucositis, aiming to solve prevention problem of chemotherapy-induced oral mucositis. The oral liquid comprises is characterized by being prepared from Chinese herbs and comprising the following Chinese herbs by weight: 6-10 parts of Radix Serissae, 8-15 parts of Fructus Ligustri Lucidi, 8-15 parts of Ficus virens, 6-10 parts of Radix Rehmanniae, 6-10 parts of Radix Scrophulariae, 8-15 parts of Radix Ophiopogonis, 6-10 parts of Radix Adenophorae, 8-15 parts of Rhizoma Anemarrhenae and 3-6 parts of Herba Pileae Scriptae. Clinical tests prove that the oral care liquid has good effect in preventing chemotherapy-induced oral mucositis, and is suitable for clinical application and popularization.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicine, in particular to an oral care solution for preventing oral mucositis caused by chemotherapy. Background technique [0002] Oral mucositis (OM) refers to the inflammatory and ulcerative reaction of the oral cavity. It is one of the more common and serious complications of chemotherapy in patients with malignant tumors. The incidence of stomatitis in patients with conventional chemotherapy is as high as 40%. The incidence of stomatitis is higher in patients with head and neck tumors and combined chemotherapy. The main symptoms are local pain and loss of taste, especially after eating, talking, and encountering cold, hot, sour, sweet and other stimuli. It directly affects the patient's eating and brings great misery to the patient. At the same time, treatment will be delayed and the dose of chemotherapy drugs will be reduced, which will adversely affect the prognosis. Severe oral mucos...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): A61K36/8968A61P1/02
Inventor 张秀香
Owner 威海市妇女儿童医院
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com