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Application of twotooth achyranthes aqueous extract to preparation of estrogen medicines

The technology of Achyranthes bidentata and its water extract is applied in the application field of the water extract of Achyranthes bidentata in the preparation of estrogen drugs, achieving the effects of low cost, great clinical significance and simple preparation method

Inactive Publication Date: 2012-12-05
HENAN UNIV OF CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, there is no report on the research on the estrogen-like effect of Achyranthes bidentata

Method used

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  • Application of twotooth achyranthes aqueous extract to preparation of estrogen medicines
  • Application of twotooth achyranthes aqueous extract to preparation of estrogen medicines
  • Application of twotooth achyranthes aqueous extract to preparation of estrogen medicines

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0012] In the implementation of the present invention, the water extract of Achyranthes bibentata Bl. is to decoct 100 g of Achyranthes bibentata Bl. with 10 times its weight of water 1000 g (i.e. 1000 mL) twice, each time for 2 hours, Combine two water decoctions, concentrate and dry under reduced pressure to obtain the extract-like water extract of Achyranthes bidentata, repeat three times in a row, and the average yield is 68.76%. Related diseases caused by abnormal secretion of sex hormones, such as climacteric syndrome in women.

Embodiment 2

[0014] In the specific implementation of the present invention, the water extract of Achyranthes bibentata Bl. is to decoct 200 g of Achyranthes bibentata Bl. with 2000 g of water 10 times its weight (i.e. 2000 mL), for 2 hours each time, The two water decoctions were combined, concentrated and dried under reduced pressure to obtain the extract-like water extract of Achyranthes bidentata, which was repeated three times in a row, with an average yield of 68.58%. The water extract can be used to prepare estrogen drugs.

Embodiment 3

[0016] In the specific implementation of the present invention, the water extract of Achyranthes bibentata Bl. is to decoct 300 g of Achyranthes bibentata Bl. with 3000 g of water 10 times its weight (ie 3000 mL) twice, each time for 2 hours, The two water decoctions were combined, concentrated and dried under reduced pressure to obtain the extract-like water extract of Achyranthes bidentata, which was repeated three times in a row, with an average yield of 68.29%. The water extract can be used to prepare estrogen drugs.

[0017] According to the above method, any amount of Achyranthes bidentata water extract can be prepared by industrial production according to the ratio of Achyranthes achyranthes and water, which can be used to prepare estrogen drugs, and effectively solve diseases caused by abnormal estrogen secretion in the body (such as women Menopausal syndrome, etc.), and has been fully proved by the test, the relevant test data are as follows:

[0018] First of all, th...

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Abstract

The invention relates to application of twotooth achyranthes aqueous extract to preparation of estrogen medicines. By the twotooth achyranthes aqueous extract, medicines for treating diseases caused by inappropriate secretion of estrogen in a human body can be effectively prepared. According to the technical scheme, twotooth achyranthes is decocted in water in an amount which is 10 times the weight of twotooth achyranthes twice, for two hours each time, water decoctions which are obtained twice are mixed, and the mixed water decoction is concentrated under reduction pressure and dried to form twotooth achyranthes extractum aqueous extract; the twotooth achyranthes aqueous extract can be effectively used for preparing medicines for preventing relevant diseases caused by inappropriate secretion of estrogen in the human body, so that the application of the twotooth achyranthes aqueous extract to preparation of the medicines for treating the relevant diseases caused by the inappropriate secretion of estrogen in the human body can be realized; a preparation method for the aqueous extract is simple, stable and reliable; through multiple times of experiments, the same or similar results are obtained; the method is convenient and low in cost; and the aqueous extract can be effectively used for preparing the estrogen medicines, new medicinal application of twotooth achyranthes is developed, and great clinical significance is brought.

Description

technical field [0001] The invention relates to a new application of medicine, in particular to the application of the water extract of Achyranthes bidentata in the preparation of estrogen drugs. Background technique [0002] Achyranthes bibentata is the dry root of Achyranthes bibentata Bl. Achyranthes bidentata is produced in four states, Hubei, Shaanxi and other provinces, but the quality of Achyranthes bidentata is the best, and the quantity ranks first in the country. Achyranthes bidentata is named after it was produced in the historical Huaiqing Prefecture, which is located in Henan today. Jiaozuo area. The characteristics of Achyranthes bidentata are: the slivers are thick, bright, bright in color and oily. Famous scholars of all dynasties have discussed and studied it, thinking that it is flat in nature, bitter, sweet, and sour. Return liver, kidney meridian, have liver and kidney invigorating, strong muscles and bones, inducing diuresis to relieve stranguria, the...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/21A61P5/30A61P15/12
Inventor 郑晓珂冯卫生蒋贇刘朝妍王小兰
Owner HENAN UNIV OF CHINESE MEDICINE
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