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Application of composition of Chinese yarn polysaccharide and Chinese yarn protein

A technology of yam protein and yam polysaccharide, which is applied in the direction of drug combination, peptide/protein composition, medical preparations containing active ingredients, etc.

Inactive Publication Date: 2014-05-07
新疆乐美健生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] The natural composition of yam polysaccharide and yam protein is the active ingredient extracted from the rhizome of the yam plant of the genus Dioscorea in the family Dioscorea. It is pointed out in (Patent No. ZL201010171536.1) that it has the effect of treating sleep apnea syndrome. The present invention is based on this Further studies have shown that: yam polysaccharides and yam protein compositions have good effects on the main components of metabolic syndrome, obesity, insulin resistance, type 2 diabetes, hyperlipidemia, hypertension, fatty liver and the resulting heart and kidney damage. Therapeutic and protective effects of yam polysaccharide and yam protein composition are derived from natural plants, the drug source is sufficient, and the extraction and preparation method is simple and easy. It can be made into various dosage forms such as capsules, tablets, granules, and oral liquids. Effectively treat heart and kidney damage caused by obesity, insulin resistance, type 2 diabetes, hyperlipidemia, high blood pressure, fatty liver and the above-mentioned component diseases of metabolic syndrome, but so far, no see related reports

Method used

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  • Application of composition of Chinese yarn polysaccharide and Chinese yarn protein
  • Application of composition of Chinese yarn polysaccharide and Chinese yarn protein
  • Application of composition of Chinese yarn polysaccharide and Chinese yarn protein

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0015] a. Use the dried rhizome of yam crude drug as raw material, remove plant impurities, weigh 10 kg and pulverize it, heat it with water twice the weight of yam at a temperature of 50°C, reflux extraction twice for 2 hours, filter, and combine the extracts , concentrate the extract to 50% after filtering;

[0016] b. Add 95% ethanol to the concentrated solution to make the alcohol content of the concentrated solution reach 30%, and remove the precipitate after precipitation occurs;

[0017] c. Continue to add 95% ethanol to the concentrated solution to make the alcohol content reach 90%. After the precipitate appears, let it stand for 3 hours. After the precipitate is fully precipitated, remove the supernatant to collect the precipitate, then dry it and crush it. , the yellow-brown powder yam polysaccharide content of 40-50% and the composition of yam protein content of 30-40% can be obtained.

Embodiment 2

[0019] a. Use the dried rhizome of yam crude drug as raw material, remove plant impurities, weigh 10 kg and pulverize, heat with water 5 times the weight of yam, temperature 100°C, reflux extraction 3 times for 3 hours, filter, and combine the extracts , filtered, concentrated to 50%;

[0020] b. Add 95% ethanol to the concentrated solution to make the alcohol content of the concentrated solution reach 30%, and remove the precipitate after precipitation occurs;

[0021] c. Continue to add 95% ethanol to the concentrated solution to make the alcohol content reach 90%. After the precipitate appears, let it stand for 6 hours. After the precipitate is fully precipitated, remove the supernatant to collect the precipitate, then dry it and crush it. , the yellow-brown powder yam polysaccharide content of 40-50% and the composition of yam protein content of 30-40% can be obtained.

Embodiment 3

[0023] a. Take the dried rhizome of Chinese yam as a raw material, remove plant impurities, weigh 10 kilograms and pulverize it, heat it with water 3.5 times the weight of Chinese yam, at a temperature of 80° C., reflux and extract 3 times for 2.5 hours, filter, and combine the extracts, Filter and concentrate to 50%;

[0024] b. Add 95% ethanol to the concentrated solution to make the alcohol content of the concentrated solution reach 30%, and remove the precipitate after precipitation occurs;

[0025] c. Continue to add 95% ethanol to the concentrated solution to make the alcohol content reach 90%. After the precipitate appears, let it stand for 4.5 hours. After the precipitate is fully precipitated, remove the supernatant to collect the precipitate, then dry it and crush it. , the yellow-brown powder yam polysaccharide content of 40-50% and the composition of yam protein content of 30-40% can be obtained.

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Abstract

Disclosed in the present invention is the use of a composition of Yam polysaccharides and Yam proteins. After summarizing and analyzing a large number of clinical observations and animal experiments, the composition of Yam polysaccharides and Yam proteins is proven to be able to treat metabolic syndromes characterized by obesity, insulin resistance, hypertension, hyperlipidemia, fatty liver and damage to the heart and kidneys caused thereby.

Description

technical field [0001] The present invention relates to the purposes of the composition of a kind of yam polysaccharide and yam protein, specifically, relate to the natural composition of yam polysaccharide and yam protein in the preparation treatment of obesity, insulin resistance, type 2 diabetes, hypertension, hyperlipidemia, fat Use in drugs for metabolic syndrome characterized by liver and its resulting cardiac and renal damage. Background technique [0002] Metabolic syndrome is composed of obesity, especially abdominal obesity, lipid metabolism disorders (elevated triglycerides, elevated low-density lipoproteins), glucose metabolism disorders (impaired glucose tolerance, type 2 diabetes), hypertension and other diseases Disease group, as early as the 1950s, some international medical scientists observed that obesity, especially abdominal obesity, is often accompanied by lipid metabolism disorders, glucose metabolism disorders and high blood pressure, and the above dis...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K38/00A61K36/8945A61P3/04A61P3/10A61P9/12A61P3/06A61P1/16A61P9/00A61P13/12A61K31/715
CPCA61K38/00A61K36/8945A61P1/16A61P3/04A61P3/06A61P3/10A61P9/00A61P9/12A61P13/12
Inventor 多力坤·马木特
Owner 新疆乐美健生物科技有限公司