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15results about How to "Avoid Oxidative Damage" patented technology

Armadillidiam vulgare derived carbon quantum dots as well as preparation method and application thereof

The invention relates to armadillidiam vulgare derived carbon quantum dots as well as a preparation method and application thereof, the armadillidiam vulgare derived carbon quantum dots are characterized in that the particle size of the armadillidiam vulgare derived carbon quantum dots is 2.2-6.0 nm, and the armadillidiam vulgare derived carbon quantum dots can inhibit pain response, reduce oxidative stress level and reduce inflammatory factor gene expression level. The armadillidiam vulgare derived analgesic carbon quantum dots inhibit irritant movement and oxidative damage in a pain model, and reduce inflammatory factors and pain pathway gene expression; the oxidative stress level is reduced, and the effects of relieving pain, resisting inflammation and resisting oxidative stress are achieved.
Owner:NORTHEAST NORMAL UNIVERSITY

A kind of preparation method of Lactobacillus casei and preparation thereof

The present invention discloses a method for preparing Lactobacillus casei and a preparation thereof. The Lactobacillus casei was deposited in the China General Microbiological Culture Collection Center on July 6, 2022, with a deposit number of CGMCC No. 25194. The preparation method of the double-layer emulsion probiotic preparation comprises the following steps: (1) vortexing Lactobacillus casei and a probiotic protective agent solution to uniformly disperse them to form an inner water phase W1; (2) dissolving ursolic acid in oil to form an oil phase O, and mixing the oil phase O with the inner water phase W1 by high-speed shearing to obtain an oil-in-water type colostrum W1 / O; (3) using a suspension of colloidal particles as an external water phase W2, adding the external water phase W2 to the colostrum W1 / O, and mixing by medium-speed shearing to obtain a double-layer emulsion probiotic preparation with a W1 / O / W2 type double emulsion structure.
Owner:HUNAN AGRI UNIV

Tilapia skin peptide, preparation method thereof and application of tilapia skin peptide in preparation of anti-aging related products

The invention belongs to the technical field of biology, and particularly relates to tilapia skin peptide, a preparation method thereof and application of the tilapia skin peptide in preparation of anti-aging related products. The tilapia skin peptide disclosed by the invention is IL, FGP or LPGL. In the invention, the tilapia skin is subjected to enzymolysis to prepare protein peptide, a peptide fragment with high content and high reliability is selected through mass spectrum identification, and a pure product is prepared by using a solid-phase chemical synthesis method. And by taking GPH as a positive control group, IL, FGP and LPGL are found to have a protection effect on UV-induced cell injury, have good antioxidant activity and an effect of repairing injured cells, and are beneficial to protecting a skin barrier and delaying skin aging.
Owner:BEIJING QINGYAN BOSHI HEALTH MANAGEMENT CO LTD

A coating and its preparation method and application, and coated product

The present invention belongs to the technical field of polymer materials, and specifically discloses a coating, a preparation method and application thereof, and a coated product. The raw material components of the coating of the present invention include: 30 to 105 parts of epoxy resin, 1 to 100 parts of a curing agent composition, and 0.3 to 100 parts of a flaky filler composition; wherein the flaky filler composition includes flaky mica powder, flaky glass flakes, and flaky andalusite. The present invention modifies the coating by adding flaky fillers, and a laminated structure can be formed in the coating, thereby improving the barrier and shielding capabilities of the coating, and further optimizing the formula of the flaky filler component, so as to achieve the effect of enhancing the water resistance, heat resistance, corrosion resistance, and extending the service life of the epoxy resin coating; the anti-corrosion coating and coated product prepared by the coating have the characteristics of high coating density, strong anti-permeability, and high heat resistance, and can meet the application requirements in harsh environments such as high humidity and heat, acid and alkali corrosion.
Owner:FOSHAN SHUNDE MIDEA WASHING APPLIANCES MANUFACTURING CO LTD +1

Central control wire harness rubber protection assembly

PendingCN121965380ASimple and convenient splicing installationAvoid the inconvenience of placing the sleeve on the outside of the cableElectrical apparatusElectric/fluid circuitStructural engineeringMechanical engineering
The invention provides a central control wire harness rubber protection assembly, and relates to the technical field of central control wire harness protection. A connecting mechanism is fixedly arranged on the outer side of each rubber shell, a locking device is fixedly arranged on the outer side of each rubber shell, and a sealing device is arranged between the two sets of rubber shells. A heat dissipation device is fixedly arranged in the rubber shell, a connecting device is fixedly arranged at the bottom of a locking device, an adjusting mechanism is fixedly arranged on the inner side of the connecting device, and a joining mechanism, the locking device, the adjusting mechanism and the connecting device are arranged; the rubber shell can be simply and conveniently spliced and installed, and the phenomenon that the rubber protection assembly is inconvenient to sleeve the outer side of the cable due to the fact that the wire harness connector is larger than the outer diameter of the cable is avoided; and the wire harness can be supported according to the angle of the wire harness. The problems that during use, splicing is not convenient, and a rubber protection assembly is generally not provided with a supporting structure are solved.
Owner:YANCHENG HUAYUE AUTO PARTS CO LTD

Copper-manganese bimetallic fiber catalyst as well as preparation method and application thereof

The invention belongs to the technical field of new materials, and discloses a copper-manganese bimetallic fiber catalyst and a preparation method and application thereof.The preparation method specifically comprises the steps that copper ions and manganese ions are loaded on polymer fibers, and copper-manganese-loaded polymer fibers are obtained; s2, roasting the copper-manganese-loaded polymer fiber prepared in the step S1 in an inert gas atmosphere to obtain a copper-manganese bimetallic fiber catalytic material precursor; and S2, carrying out ozone in-situ activation treatment on the copper-manganese bimetallic fiber catalytic material precursor prepared in the step S2 by adopting ozone airflow to obtain the copper-manganese-based fiber catalyst. The prepared catalyst is high in catalytic activity, good in water vapor resistance and high in thermal oxidation stability, in addition, the selection of forms is not limited, the catalyst can be applied in any forms such as disordered fibers, woolen yarns, needle-punched fabrics and knitted fabrics, filling is convenient, and the use depth and range of catalytic materials are greatly widened.
Owner:HENAN ACADEMY OF SCI CHEM RES INST CO LTD +1

Composite basic manganese chloride as well as preparation method and application thereof

The invention discloses composite basic manganese chloride as well as a preparation method and application thereof, and belongs to the technical field of preparation of inorganic chemical products. The raw materials used in the preparation method are wide in source and lower in price, and the production process is simple in step and high in yield, so that the production cost is low; in addition, the preparation method provided by the invention comprises an impurity removal step, the content of harmful ions in the finally obtained basic manganese chloride product is extremely low, and adverse effects on animals and plants are not generated after the basic manganese chloride product is used; a nucleating agent and a surfactant are introduced in the preparation process, so that the product with a narrow and uniform particle size distribution range can be obtained, specific nutritional ingredients can be introduced into the product, and meanwhile, high-valence manganese ingredients can be prevented from being generated in the drying process, so that the obtained product is more easily absorbed and utilized by animals and plants; therefore, the obtained product can be better used as feed or plant fertilizer.
Owner:JIANGXI HILLMAN NEW ENERGY TECH CO LTD

Wafer conveying device of photoetching machine

The invention relates to a wafer conveying device of a photoetching machine, and belongs to the technical field of semiconductor manufacturing, the wafer conveying device comprises a conveying guide rail fixed with an external supporting structure, a lifting frame is slidably mounted at the bottom of the conveying guide rail, a transfer assembly is fixed at the bottom of the lifting frame through a middle column, the transfer assembly comprises a transverse plate body, and a supporting plate is slidably clamped on the transverse plate body; the number of the supporting plates is three, a power mechanism used for controlling the supporting plates to slide is installed at the bottom of the transverse plate body, one end of the conveying guide rail is located above a transfer site, the other end of the conveying guide rail is located above a target site, a protection box is arranged below the conveying guide rail, and a lower conveying assembly is fixed to the bottom in the protection box. The transport device can be conveniently transported at two places, unnecessary occupation of space is reduced, the transport device can move and ascend and descend, transfer and placement of wafers are further facilitated, protective gas can be introduced into the protective box, and particularly, the wafers can be protected from being oxidized and damaged when the wafers need to be temporarily stored.
Owner:NANJING TAIHUIMIAO BIOTECHNOLOGY CO LTD

A method for decolorizing steroid intermediate dihydroxy compounds

PendingCN122080104AAvoid Oxidative DamageDecolorization achievedSteroidsHydrocarbon solventsActivated carbon
This invention provides a method for decolorizing a steroid intermediate dihydroxy compound, relating to the field of pharmaceutical and chemical technology. The method includes: dissolving the crude dihydroxy compound in a halogenated hydrocarbon solvent; adjusting the pH of the system to 8.0-9.5 with an inorganic base; adding an aqueous sodium hypochlorite solution for chemical oxidation decolorization while maintaining this pH value; determining the reaction endpoint by monitoring color change or redox potential; adjusting the pH after the reaction with a weak acid, followed by separation, concentration, and crystallization to obtain the final product. This invention utilizes the selective oxidation effect of sodium hypochlorite in a specific pH buffer system, replacing the traditional physical adsorption decolorization with activated carbon. While effectively removing fermentation pigments, it avoids the oxidative damage of the 11-hydroxyl group in the steroid skeleton. The product has high purity, produces no waste activated carbon solid waste, is simple to operate, and is easily scaled up industrially.
Owner:YUNNAN ZEWEI PHARM CO LTD

Small molecule compound composition and application thereof

The invention relates to a small molecule compound composition and application thereof, and belongs to the technical field of biology. The small molecule compound composition provided by the invention comprises NU7441, GW9662 and D609 or stereoisomers thereof. It is found for the first time that the small molecule compound combination can effectively inhibit oxidative damage caused by hypertonic to corneal epithelial cells, and the survival rate of the corneal epithelial cells is remarkably increased. Animal in-vivo experiments show that compared with a control group, an experimental group which is subjected to injection of scopolamine dry eye model mice and is subjected to eye drop of the small molecule compound combination eye drop at the same time has the advantages that corneal defects are obviously reduced, tear secretion is increased, the small molecule compound combination can effectively prevent corneal epithelium injury, the drug effect is relatively high, and no obvious drug toxicity exists; the small molecule compound combination may become a strong and effective medicine for clinically treating dry eye in the future.
Owner:ZHONGSHAN OPHTHALMIC CENT SUN YAT SEN UNIV

Comprehensive treatment method and system for improving germination rate of epimedium seeds

The invention discloses a comprehensive treatment method and system for improving the germination rate of epimedium seeds. The method comprises the following steps: S1, intelligently judging the harvesting time; s2, standardized after-ripening treatment: putting the harvested seeds with fruits in a ventilated environment with the temperature of 20-22 DEG C and the humidity of 50%-60% for in-vitro after-ripening, and turning every day until the fruit state reaches a preset after-ripening end point; s3, dynamic controlled atmosphere storage: mixing the seeds subjected to after-ripening treatment with sterilized river sand, storing in a controlled atmosphere environment with the temperature of 6-10 DEG C and the CO2 concentration of 5%, regularly ventilating, and adding a vitamin E preservative into the mixed matrix; s4, breaking dormancy and accelerating germination; and S5, process monitoring and parameter optimization. According to the method, a double-channel intelligent judgment model of image form recognition and physiological index (soluble sugar) detection is constructed, the limitation of purely depending on appearance experience is overcome, form maturity and physiological maturity indexes are combined, the optimal initial quality of the harvested seeds is ensured, and a foundation is laid for the high germination rate from the source.
Owner:HUILI COUNTY JIAHE AGRI CO LTD

Vincristine sulfate injection and preparation method thereof

The invention provides a vincristine sulfate injection and a preparation method thereof, and relates to the technical field of pharmaceutical preparations. The preparation method of the vincristine sulfate injection comprises the following steps: (1) adding vincristine sulfate and rosmarinic acid into an acetate buffer solution, uniformly stirring and mixing, filtering, collecting powder, drying, grinding and sieving to obtain a vincristine sulfate-rosmarinic acid eutectic; (2) adding mannitol into the water for injection for later use; and (3) adding the vincristine sulfate-rosmarinic acid eutectic into the system in the step (2), stirring, adjusting the pH value to 4.5-5.5, filtering with a microporous membrane, sterilizing, and filling to obtain the vincristine sulfate injection. The vincristine sulfate injection disclosed by the invention is simple in preparation process, good in reproducibility and easy for industrial production. The vincristine sulfate injection has the advantages of simple raw materials, no need of any synthetic carrier material, definite components and high safety, and the prepared vincristine sulfate injection has high stability and good application prospects.
Owner:HAINAN ZHUOTAI PHARM CO LTD

Lactobacillus plantarum IOB602 for regulating bone metabolism and application thereof

ActiveCN119157912BReduce MDA contentlower levelBacteriaMetabolism disorder
The present invention provides a plant lactobacillus IOB602 for regulating bone metabolism and its application, and relates to the field of microbial technology. Lactiplantibacillus plantarum , was deposited in the General Microbiology Center of China Microorganism Culture Collection Committee on June 29, 2018, referred to as CGMCC, and the deposit address is No. 3, No. 1 Beichen West Road, Chaoyang District, Beijing, and the deposit number is CGMCC No. 16021. The bacteria reduces the content of lipid peroxidation product malondialdehyde and increases the content of antioxidant enzymes, which is of great significance for reducing ROS damage to bone cells, regulating the balance of osteoblasts and osteoclasts, improving bone metabolism, and preventing and treating diabetic osteoporosis.
Owner:TIANJIN INNOORIGIN BIOLOGICAL TECH CO LTD +1

Anti-oxidation emergency equipment cabinet

The invention discloses an anti-oxidation emergency equipment cabinet, and relates to the technical field of emergency equipment storage. The cabinet specifically comprises a cabinet body and a cabinet door, the cabinet body is used for storing emergency equipment, the cabinet door is used for sealing the cabinet body, the cabinet further comprises an inert gas tank, the inert gas tank is communicated with the cabinet body through a pipeline and used for discharging inert gas into the cabinet body, and the cabinet body is filled with the inert gas. The cabinet body and the stored emergency equipment are protected through inert gas, the pipeline is provided with a low-leakage high-sealing valve, and the inert gas is slowly released through the low-leakage high-sealing valve. Inert gas can be continuously discharged into the cabinet body, so that the cabinet body is always filled with the inert gas, the cabinet body is protected by the inert gas, and the emergency equipment is prevented from being oxidized and damaged.
Owner:THREE GORGES JINSHAJIANG CHUANYUN HYDROPOWER DEV CO LTD

Welding tool and welding method

The invention discloses a welding tool which comprises a back protection gas tool and a water cooling tool, the back protection gas tool is used for introducing protection gas into the back face of a welding seam, the water cooling tool is used for transferring refrigerants, the back protection gas tool is matched with the water cooling tool and used for providing plating protection conditions for a welding workpiece, and the back protection gas tool comprises an upper bottom plate and a lower bottom plate; an outer circular ring is welded to the outer edges of the upper bottom plate and the lower bottom plate, and the upper bottom plate, the lower bottom plate and the outer circular ring form an annular cavity. According to the welding tool, the back protection gas tool and the water cooling tool are matched with each other, a copper plating layer, near a weld groove, of the barrel can be protected, the copper plating layer is prevented from being oxidized and damaged in the welding process, and accurate welding of a workpiece is achieved; the welding tool is matched with the welding method, accurate positioning and stable welding of the workpiece can be achieved, the welding quality and efficiency can be improved while a copper plating layer near a welding groove is protected, and the design quality use requirement is met.
Owner:HEFEI JUNENG ELECTRO PHYSICS HIGH-TECH DEV CO LTD